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  - biology
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  size_categories:
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  - 1B<n<10B
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  - biology
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  size_categories:
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  - 1B<n<10B
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+ ---
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+ # Dataset Card for GuideRNA-3B
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+ ## Dataset Description
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+ - **Homepage:** https://github.com/bm2-lab/CRISPR-viva
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+ - **Repository:** https://github.com/bm2-lab/CRISPR-viva
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+ - **Contact:** 18alexanderm117@tongji.edu.cn
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+ ### Dataset Summary
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+ **GuideRNA-3B** is a large transcriptome sequence corpus consisting of over 3.7 billion paired sequences extracted from the specific transcriptome of 23 cell lines and over 200 segmented genomes of RNA virus.
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+ ### Supported Tasks
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+ Based on this nucleotide sequence corpus, we are able to establish a foundation model to characterize the manifold of CRISPR guide RNA targeting regions in order to undertake further downstreaming task for universal CRISPR-based RNA virus amplification-free detection and inhibition.
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+ For details, please refer to [our paper](https://github.com/bm2-lab/CRISPR-viva) and [website](https://github.com/bm2-lab/CRISPR-viva).
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+ ### Languages
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+ English (en).
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+ ## Dataset Structure
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+ ### jsonl-based Arrow
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+ These files are compressed Arrow-formated sourced from JSON-lined text file data, with the following columns:
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+ - `before`: string. Nucleotide sequence from transcriptome of cell line or RNA virus.
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+ - `next`: string. Nucleotide sequence with postion right-shifted by one.
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+ ### Citation Information
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+ If you find **GuideRNA-3B** helpful in your research, please cite our work by: