---
license: apache-2.0
tags:
- biology
size_categories:
- 1B<n<10B
---

# Dataset Card for GuideRNA-3B

## Dataset Description

- **Homepage:** https://github.com/bm2-lab/CRISPR-viva
- **Repository:** https://github.com/bm2-lab/CRISPR-viva
- **Contact:** 18alexanderm117@tongji.edu.cn

### Dataset Summary

**GuideRNA-3B** is a large transcriptome sequence corpus consisting of over 3.7 billion paired sequences extracted from the specific transcriptome of 23 cell lines and over 200 segmented genomes of RNA virus.


### Supported Tasks

Based on this nucleotide sequence corpus, we are able to establish a foundation model to characterize the manifold of CRISPR guide RNA targeting regions in order to undertake further downstreaming task for universal CRISPR-based RNA virus amplification-free detection and inhibition. 
For details, please refer to [our paper](https://github.com/bm2-lab/CRISPR-viva) and [website](https://github.com/bm2-lab/CRISPR-viva).

### Languages

English (en).

## Dataset Structure

### jsonl-based Arrow

These files are compressed Arrow-formated sourced from JSON-lined text file data, with the following columns:

- `before`: string. Nucleotide sequence from transcriptome of cell line or RNA virus.
- `next`: string. Nucleotide sequence with postion right-shifted by one.


### Citation Information

If you find **GuideRNA-3B** helpful in your research, please cite our work by: