id
stringlengths
1
6
document_id
stringclasses
1 value
passages
list
entities
list
events
list
coreferences
list
relations
list
13400
NULL
[]
[ { "id": "13401", "type": "0", "text": [ "We" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "13402", "type": "0", "text": [ "," ], "offsets": [ [ 5, 6 ] ], "normalized": [] }, { "id": "13403", "type": "0", "text": [ "therefore" ], "offsets": [ [ 15, 24 ] ], "normalized": [] }, { "id": "13404", "type": "0", "text": [ "," ], "offsets": [ [ 17, 18 ] ], "normalized": [] }, { "id": "13405", "type": "0", "text": [ "compared" ], "offsets": [ [ 26, 34 ] ], "normalized": [] }, { "id": "13406", "type": "0", "text": [ "the" ], "offsets": [ [ 30, 33 ] ], "normalized": [] }, { "id": "13407", "type": "0", "text": [ "activation" ], "offsets": [ [ 41, 51 ] ], "normalized": [] }, { "id": "13408", "type": "0", "text": [ "state" ], "offsets": [ [ 47, 52 ] ], "normalized": [] }, { "id": "13409", "type": "0", "text": [ "of" ], "offsets": [ [ 50, 52 ] ], "normalized": [] }, { "id": "13410", "type": "0", "text": [ "the" ], "offsets": [ [ 54, 57 ] ], "normalized": [] }, { "id": "13411", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 59, 63 ] ], "normalized": [] }, { "id": "13412", "type": "2", "text": [ "gene" ], "offsets": [ [ 64, 68 ] ], "normalized": [] }, { "id": "13413", "type": "2", "text": [ "promoter" ], "offsets": [ [ 73, 81 ] ], "normalized": [] }, { "id": "13414", "type": "2", "text": [ "region" ], "offsets": [ [ 80, 86 ] ], "normalized": [] }, { "id": "13415", "type": "0", "text": [ "in" ], "offsets": [ [ 83, 85 ] ], "normalized": [] }, { "id": "13416", "type": "0", "text": [ "freshly" ], "offsets": [ [ 91, 98 ] ], "normalized": [] }, { "id": "13417", "type": "0", "text": [ "isolated" ], "offsets": [ [ 100, 108 ] ], "normalized": [] }, { "id": "13418", "type": "0", "text": [ "and" ], "offsets": [ [ 104, 107 ] ], "normalized": [] }, { "id": "13419", "type": "0", "text": [ "stimulated" ], "offsets": [ [ 115, 125 ] ], "normalized": [] }, { "id": "13420", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "13421", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 126, 132 ] ], "normalized": [] }, { "id": "13422", "type": "6", "text": [ "T" ], "offsets": [ [ 128, 129 ] ], "normalized": [] }, { "id": "13423", "type": "6", "text": [ "cells" ], "offsets": [ [ 134, 139 ] ], "normalized": [] }, { "id": "13424", "type": "0", "text": [ "with" ], "offsets": [ [ 139, 143 ] ], "normalized": [] }, { "id": "13425", "type": "0", "text": [ "that" ], "offsets": [ [ 144, 148 ] ], "normalized": [] }, { "id": "13426", "type": "0", "text": [ "of" ], "offsets": [ [ 147, 149 ] ], "normalized": [] }, { "id": "13427", "type": "7", "text": [ "normal" ], "offsets": [ [ 154, 160 ] ], "normalized": [] }, { "id": "13428", "type": "8", "text": [ "T" ], "offsets": [ [ 156, 157 ] ], "normalized": [] }, { "id": "13429", "type": "8", "text": [ "lymphocytes" ], "offsets": [ [ 168, 179 ] ], "normalized": [] }, { "id": "13430", "type": "0", "text": [ "." ], "offsets": [ [ 170, 171 ] ], "normalized": [] } ]
[]
[]
[]
13431
NULL
[]
[ { "id": "13432", "type": "0", "text": [ "Levels" ], "offsets": [ [ 7, 13 ] ], "normalized": [] }, { "id": "13433", "type": "0", "text": [ "of" ], "offsets": [ [ 10, 12 ] ], "normalized": [] }, { "id": "13434", "type": "0", "text": [ "the" ], "offsets": [ [ 14, 17 ] ], "normalized": [] }, { "id": "13435", "type": "0", "text": [ "octamer" ], "offsets": [ [ 22, 29 ] ], "normalized": [] }, { "id": "13436", "type": "0", "text": [ "," ], "offsets": [ [ 24, 25 ] ], "normalized": [] }, { "id": "13437", "type": "9", "text": [ "NF-kappa" ], "offsets": [ [ 33, 41 ] ], "normalized": [] }, { "id": "13438", "type": "10", "text": [ "B" ], "offsets": [ [ 35, 36 ] ], "normalized": [] }, { "id": "13439", "type": "0", "text": [ "(" ], "offsets": [ [ 37, 38 ] ], "normalized": [] }, { "id": "13440", "type": "9", "text": [ "p50-p65" ], "offsets": [ [ 45, 52 ] ], "normalized": [] }, { "id": "13441", "type": "10", "text": [ "heterodimer" ], "offsets": [ [ 57, 68 ] ], "normalized": [] }, { "id": "13442", "type": "0", "text": [ ")" ], "offsets": [ [ 59, 60 ] ], "normalized": [] }, { "id": "13443", "type": "0", "text": [ "," ], "offsets": [ [ 61, 62 ] ], "normalized": [] }, { "id": "13444", "type": "0", "text": [ "and" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "13445", "type": "9", "text": [ "AP-1" ], "offsets": [ [ 70, 74 ] ], "normalized": [] }, { "id": "13446", "type": "10", "text": [ "transcriptional" ], "offsets": [ [ 86, 101 ] ], "normalized": [] }, { "id": "13447", "type": "10", "text": [ "factors" ], "offsets": [ [ 94, 101 ] ], "normalized": [] }, { "id": "13448", "type": "0", "text": [ "are" ], "offsets": [ [ 98, 101 ] ], "normalized": [] }, { "id": "13449", "type": "0", "text": [ "constitutively" ], "offsets": [ [ 113, 127 ] ], "normalized": [] }, { "id": "13450", "type": "0", "text": [ "elevated" ], "offsets": [ [ 122, 130 ] ], "normalized": [] }, { "id": "13451", "type": "0", "text": [ "in" ], "offsets": [ [ 125, 127 ] ], "normalized": [] }, { "id": "13452", "type": "0", "text": [ "freshly" ], "offsets": [ [ 133, 140 ] ], "normalized": [] }, { "id": "13453", "type": "0", "text": [ "isolated" ], "offsets": [ [ 142, 150 ] ], "normalized": [] }, { "id": "13454", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 146, 149 ] ], "normalized": [] }, { "id": "13455", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 153, 159 ] ], "normalized": [] }, { "id": "13456", "type": "6", "text": [ "T" ], "offsets": [ [ 155, 156 ] ], "normalized": [] }, { "id": "13457", "type": "6", "text": [ "cells" ], "offsets": [ [ 161, 166 ] ], "normalized": [] }, { "id": "13458", "type": "0", "text": [ "," ], "offsets": [ [ 163, 164 ] ], "normalized": [] }, { "id": "13459", "type": "0", "text": [ "consistent" ], "offsets": [ [ 174, 184 ] ], "normalized": [] }, { "id": "13460", "type": "0", "text": [ "with" ], "offsets": [ [ 179, 183 ] ], "normalized": [] }, { "id": "13461", "type": "0", "text": [ "the" ], "offsets": [ [ 183, 186 ] ], "normalized": [] }, { "id": "13462", "type": "0", "text": [ "activated" ], "offsets": [ [ 193, 202 ] ], "normalized": [] }, { "id": "13463", "type": "0", "text": [ "phenotype" ], "offsets": [ [ 203, 212 ] ], "normalized": [] }, { "id": "13464", "type": "0", "text": [ "of" ], "offsets": [ [ 206, 208 ] ], "normalized": [] }, { "id": "13465", "type": "0", "text": [ "these" ], "offsets": [ [ 212, 217 ] ], "normalized": [] }, { "id": "13466", "type": "0", "text": [ "cells" ], "offsets": [ [ 218, 223 ] ], "normalized": [] }, { "id": "13467", "type": "0", "text": [ "." ], "offsets": [ [ 220, 221 ] ], "normalized": [] } ]
[]
[]
[]
13468
NULL
[]
[ { "id": "13469", "type": "0", "text": [ "Upon" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13470", "type": "0", "text": [ "stimulation" ], "offsets": [ [ 17, 28 ] ], "normalized": [] }, { "id": "13471", "type": "0", "text": [ "with" ], "offsets": [ [ 22, 26 ] ], "normalized": [] }, { "id": "13472", "type": "0", "text": [ "mitogens" ], "offsets": [ [ 31, 39 ] ], "normalized": [] }, { "id": "13473", "type": "0", "text": [ "," ], "offsets": [ [ 33, 34 ] ], "normalized": [] }, { "id": "13474", "type": "0", "text": [ "formation" ], "offsets": [ [ 43, 52 ] ], "normalized": [] }, { "id": "13475", "type": "0", "text": [ "of" ], "offsets": [ [ 46, 48 ] ], "normalized": [] }, { "id": "13476", "type": "0", "text": [ "the" ], "offsets": [ [ 50, 53 ] ], "normalized": [] }, { "id": "13477", "type": "0", "text": [ "transactivating" ], "offsets": [ [ 66, 81 ] ], "normalized": [] }, { "id": "13478", "type": "0", "text": [ "complex" ], "offsets": [ [ 74, 81 ] ], "normalized": [] }, { "id": "13479", "type": "0", "text": [ "," ], "offsets": [ [ 76, 77 ] ], "normalized": [] }, { "id": "13480", "type": "9", "text": [ "nuclear" ], "offsets": [ [ 84, 91 ] ], "normalized": [] }, { "id": "13481", "type": "10", "text": [ "factor" ], "offsets": [ [ 91, 97 ] ], "normalized": [] }, { "id": "13482", "type": "10", "text": [ "of" ], "offsets": [ [ 94, 96 ] ], "normalized": [] }, { "id": "13483", "type": "10", "text": [ "activated" ], "offsets": [ [ 104, 113 ] ], "normalized": [] }, { "id": "13484", "type": "10", "text": [ "T" ], "offsets": [ [ 106, 107 ] ], "normalized": [] }, { "id": "13485", "type": "10", "text": [ "cells" ], "offsets": [ [ 112, 117 ] ], "normalized": [] }, { "id": "13486", "type": "0", "text": [ "(" ], "offsets": [ [ 114, 115 ] ], "normalized": [] }, { "id": "13487", "type": "9", "text": [ "NF-AT" ], "offsets": [ [ 120, 125 ] ], "normalized": [] }, { "id": "13488", "type": "0", "text": [ ")" ], "offsets": [ [ 122, 123 ] ], "normalized": [] }, { "id": "13489", "type": "0", "text": [ "," ], "offsets": [ [ 124, 125 ] ], "normalized": [] }, { "id": "13490", "type": "0", "text": [ "occurs" ], "offsets": [ [ 131, 137 ] ], "normalized": [] }, { "id": "13491", "type": "0", "text": [ "with" ], "offsets": [ [ 136, 140 ] ], "normalized": [] }, { "id": "13492", "type": "0", "text": [ "normal" ], "offsets": [ [ 143, 149 ] ], "normalized": [] }, { "id": "13493", "type": "0", "text": [ "kinetics" ], "offsets": [ [ 152, 160 ] ], "normalized": [] }, { "id": "13494", "type": "0", "text": [ "in" ], "offsets": [ [ 155, 157 ] ], "normalized": [] }, { "id": "13495", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 159, 162 ] ], "normalized": [] }, { "id": "13496", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 166, 172 ] ], "normalized": [] }, { "id": "13497", "type": "6", "text": [ "T" ], "offsets": [ [ 168, 169 ] ], "normalized": [] }, { "id": "13498", "type": "6", "text": [ "cells" ], "offsets": [ [ 174, 179 ] ], "normalized": [] }, { "id": "13499", "type": "0", "text": [ "." ], "offsets": [ [ 176, 177 ] ], "normalized": [] } ]
[]
[]
[]
13500
NULL
[]
[ { "id": "13501", "type": "0", "text": [ "Yet" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "13502", "type": "0", "text": [ "," ], "offsets": [ [ 6, 7 ] ], "normalized": [] }, { "id": "13503", "type": "0", "text": [ "the" ], "offsets": [ [ 10, 13 ] ], "normalized": [] }, { "id": "13504", "type": "0", "text": [ "levels" ], "offsets": [ [ 17, 23 ] ], "normalized": [] }, { "id": "13505", "type": "0", "text": [ "of" ], "offsets": [ [ 20, 22 ] ], "normalized": [] }, { "id": "13506", "type": "0", "text": [ "the" ], "offsets": [ [ 24, 27 ] ], "normalized": [] }, { "id": "13507", "type": "0", "text": [ "activating" ], "offsets": [ [ 35, 45 ] ], "normalized": [] }, { "id": "13508", "type": "9", "text": [ "NF-AT" ], "offsets": [ [ 41, 46 ] ], "normalized": [] }, { "id": "13509", "type": "10", "text": [ "complex" ], "offsets": [ [ 49, 56 ] ], "normalized": [] }, { "id": "13510", "type": "0", "text": [ "never" ], "offsets": [ [ 55, 60 ] ], "normalized": [] }, { "id": "13511", "type": "0", "text": [ "reach" ], "offsets": [ [ 61, 66 ] ], "normalized": [] }, { "id": "13512", "type": "0", "text": [ "those" ], "offsets": [ [ 67, 72 ] ], "normalized": [] }, { "id": "13513", "type": "0", "text": [ "observed" ], "offsets": [ [ 76, 84 ] ], "normalized": [] }, { "id": "13514", "type": "0", "text": [ "in" ], "offsets": [ [ 79, 81 ] ], "normalized": [] }, { "id": "13515", "type": "0", "text": [ "similarly" ], "offsets": [ [ 89, 98 ] ], "normalized": [] }, { "id": "13516", "type": "0", "text": [ "stimulated" ], "offsets": [ [ 100, 110 ] ], "normalized": [] }, { "id": "13517", "type": "0", "text": [ "normal" ], "offsets": [ [ 107, 113 ] ], "normalized": [] }, { "id": "13518", "type": "7", "text": [ "T" ], "offsets": [ [ 109, 110 ] ], "normalized": [] }, { "id": "13519", "type": "8", "text": [ "cells" ], "offsets": [ [ 115, 120 ] ], "normalized": [] }, { "id": "13520", "type": "0", "text": [ "." ], "offsets": [ [ 117, 118 ] ], "normalized": [] } ]
[]
[]
[]
13521
NULL
[]
[ { "id": "13522", "type": "0", "text": [ "Furthermore" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "13523", "type": "0", "text": [ "," ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "13524", "type": "0", "text": [ "nuclear" ], "offsets": [ [ 22, 29 ] ], "normalized": [] }, { "id": "13525", "type": "0", "text": [ "extracts" ], "offsets": [ [ 31, 39 ] ], "normalized": [] }, { "id": "13526", "type": "0", "text": [ "from" ], "offsets": [ [ 36, 40 ] ], "normalized": [] }, { "id": "13527", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 40, 43 ] ], "normalized": [] }, { "id": "13528", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 47, 53 ] ], "normalized": [] }, { "id": "13529", "type": "6", "text": [ "T" ], "offsets": [ [ 49, 50 ] ], "normalized": [] }, { "id": "13530", "type": "6", "text": [ "cells" ], "offsets": [ [ 55, 60 ] ], "normalized": [] }, { "id": "13531", "type": "0", "text": [ "display" ], "offsets": [ [ 63, 70 ] ], "normalized": [] }, { "id": "13532", "type": "0", "text": [ "high" ], "offsets": [ [ 68, 72 ] ], "normalized": [] }, { "id": "13533", "type": "0", "text": [ "levels" ], "offsets": [ [ 75, 81 ] ], "normalized": [] }, { "id": "13534", "type": "0", "text": [ "of" ], "offsets": [ [ 78, 80 ] ], "normalized": [] }, { "id": "13535", "type": "0", "text": [ "a" ], "offsets": [ [ 80, 81 ] ], "normalized": [] }, { "id": "13536", "type": "0", "text": [ "novel" ], "offsets": [ [ 86, 91 ] ], "normalized": [] }, { "id": "13537", "type": "0", "text": [ "specific" ], "offsets": [ [ 95, 103 ] ], "normalized": [] }, { "id": "13538", "type": "0", "text": [ "binding" ], "offsets": [ [ 103, 110 ] ], "normalized": [] }, { "id": "13539", "type": "0", "text": [ "activity" ], "offsets": [ [ 112, 120 ] ], "normalized": [] }, { "id": "13540", "type": "0", "text": [ "at" ], "offsets": [ [ 115, 117 ] ], "normalized": [] }, { "id": "13541", "type": "0", "text": [ "the" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "13542", "type": "1", "text": [ "NF-AT" ], "offsets": [ [ 125, 130 ] ], "normalized": [] }, { "id": "13543", "type": "2", "text": [ "site" ], "offsets": [ [ 130, 134 ] ], "normalized": [] }, { "id": "13544", "type": "0", "text": [ "," ], "offsets": [ [ 132, 133 ] ], "normalized": [] }, { "id": "13545", "type": "0", "text": [ "which" ], "offsets": [ [ 138, 143 ] ], "normalized": [] }, { "id": "13546", "type": "0", "text": [ "is" ], "offsets": [ [ 141, 143 ] ], "normalized": [] }, { "id": "13547", "type": "0", "text": [ "present" ], "offsets": [ [ 149, 156 ] ], "normalized": [] }, { "id": "13548", "type": "0", "text": [ "at" ], "offsets": [ [ 152, 154 ] ], "normalized": [] }, { "id": "13549", "type": "0", "text": [ "much" ], "offsets": [ [ 157, 161 ] ], "normalized": [] }, { "id": "13550", "type": "0", "text": [ "lower" ], "offsets": [ [ 163, 168 ] ], "normalized": [] }, { "id": "13551", "type": "0", "text": [ "levels" ], "offsets": [ [ 170, 176 ] ], "normalized": [] }, { "id": "13552", "type": "0", "text": [ "in" ], "offsets": [ [ 173, 175 ] ], "normalized": [] }, { "id": "13553", "type": "0", "text": [ "freshly" ], "offsets": [ [ 181, 188 ] ], "normalized": [] }, { "id": "13554", "type": "0", "text": [ "isolated" ], "offsets": [ [ 190, 198 ] ], "normalized": [] }, { "id": "13555", "type": "7", "text": [ "normal" ], "offsets": [ [ 197, 203 ] ], "normalized": [] }, { "id": "13556", "type": "8", "text": [ "T" ], "offsets": [ [ 199, 200 ] ], "normalized": [] }, { "id": "13557", "type": "8", "text": [ "lymphocytes" ], "offsets": [ [ 211, 222 ] ], "normalized": [] }, { "id": "13558", "type": "0", "text": [ "." ], "offsets": [ [ 213, 214 ] ], "normalized": [] } ]
[]
[]
[]
13559
NULL
[]
[ { "id": "13560", "type": "0", "text": [ "Upon" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13561", "type": "0", "text": [ "mitogenic" ], "offsets": [ [ 15, 24 ] ], "normalized": [] }, { "id": "13562", "type": "0", "text": [ "stimulation" ], "offsets": [ [ 27, 38 ] ], "normalized": [] }, { "id": "13563", "type": "0", "text": [ "," ], "offsets": [ [ 29, 30 ] ], "normalized": [] }, { "id": "13564", "type": "0", "text": [ "the" ], "offsets": [ [ 33, 36 ] ], "normalized": [] }, { "id": "13565", "type": "0", "text": [ "binding" ], "offsets": [ [ 41, 48 ] ], "normalized": [] }, { "id": "13566", "type": "0", "text": [ "activity" ], "offsets": [ [ 50, 58 ] ], "normalized": [] }, { "id": "13567", "type": "0", "text": [ "of" ], "offsets": [ [ 53, 55 ] ], "normalized": [] }, { "id": "13568", "type": "0", "text": [ "the" ], "offsets": [ [ 57, 60 ] ], "normalized": [] }, { "id": "13569", "type": "0", "text": [ "novel" ], "offsets": [ [ 63, 68 ] ], "normalized": [] }, { "id": "13570", "type": "9", "text": [ "NF-AT-binding" ], "offsets": [ [ 77, 90 ] ], "normalized": [] }, { "id": "13571", "type": "10", "text": [ "factor" ], "offsets": [ [ 84, 90 ] ], "normalized": [] }, { "id": "13572", "type": "0", "text": [ "is" ], "offsets": [ [ 87, 89 ] ], "normalized": [] }, { "id": "13573", "type": "0", "text": [ "rapidly" ], "offsets": [ [ 95, 102 ] ], "normalized": [] }, { "id": "13574", "type": "0", "text": [ "down-regulated" ], "offsets": [ [ 110, 124 ] ], "normalized": [] }, { "id": "13575", "type": "0", "text": [ "in" ], "offsets": [ [ 113, 115 ] ], "normalized": [] }, { "id": "13576", "type": "0", "text": [ "normal" ], "offsets": [ [ 120, 126 ] ], "normalized": [] }, { "id": "13577", "type": "7", "text": [ "T" ], "offsets": [ [ 122, 123 ] ], "normalized": [] }, { "id": "13578", "type": "8", "text": [ "cells" ], "offsets": [ [ 128, 133 ] ], "normalized": [] }, { "id": "13579", "type": "0", "text": [ "," ], "offsets": [ [ 130, 131 ] ], "normalized": [] }, { "id": "13580", "type": "0", "text": [ "but" ], "offsets": [ [ 134, 137 ] ], "normalized": [] }, { "id": "13581", "type": "0", "text": [ "persists" ], "offsets": [ [ 143, 151 ] ], "normalized": [] }, { "id": "13582", "type": "0", "text": [ "at" ], "offsets": [ [ 146, 148 ] ], "normalized": [] }, { "id": "13583", "type": "0", "text": [ "high" ], "offsets": [ [ 151, 155 ] ], "normalized": [] }, { "id": "13584", "type": "0", "text": [ "levels" ], "offsets": [ [ 158, 164 ] ], "normalized": [] }, { "id": "13585", "type": "0", "text": [ "in" ], "offsets": [ [ 161, 163 ] ], "normalized": [] }, { "id": "13586", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 165, 168 ] ], "normalized": [] }, { "id": "13587", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 172, 178 ] ], "normalized": [] }, { "id": "13588", "type": "6", "text": [ "T" ], "offsets": [ [ 174, 175 ] ], "normalized": [] }, { "id": "13589", "type": "6", "text": [ "cells" ], "offsets": [ [ 180, 185 ] ], "normalized": [] }, { "id": "13590", "type": "0", "text": [ "." ], "offsets": [ [ 182, 183 ] ], "normalized": [] } ]
[]
[]
[]
13591
NULL
[]
[ { "id": "13592", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "13593", "type": "0", "text": [ "two" ], "offsets": [ [ 10, 13 ] ], "normalized": [] }, { "id": "13594", "type": "0", "text": [ "abnormalities" ], "offsets": [ [ 24, 37 ] ], "normalized": [] }, { "id": "13595", "type": "0", "text": [ "at" ], "offsets": [ [ 27, 29 ] ], "normalized": [] }, { "id": "13596", "type": "0", "text": [ "the" ], "offsets": [ [ 31, 34 ] ], "normalized": [] }, { "id": "13597", "type": "1", "text": [ "NF-AT" ], "offsets": [ [ 37, 42 ] ], "normalized": [] }, { "id": "13598", "type": "2", "text": [ "site" ], "offsets": [ [ 42, 46 ] ], "normalized": [] }, { "id": "13599", "type": "0", "text": [ "provide" ], "offsets": [ [ 50, 57 ] ], "normalized": [] }, { "id": "13600", "type": "0", "text": [ "a" ], "offsets": [ [ 52, 53 ] ], "normalized": [] }, { "id": "13601", "type": "0", "text": [ "potential" ], "offsets": [ [ 62, 71 ] ], "normalized": [] }, { "id": "13602", "type": "0", "text": [ "mechanism" ], "offsets": [ [ 72, 81 ] ], "normalized": [] }, { "id": "13603", "type": "0", "text": [ "to" ], "offsets": [ [ 75, 77 ] ], "normalized": [] }, { "id": "13604", "type": "0", "text": [ "account" ], "offsets": [ [ 83, 90 ] ], "normalized": [] }, { "id": "13605", "type": "0", "text": [ "for" ], "offsets": [ [ 87, 90 ] ], "normalized": [] }, { "id": "13606", "type": "0", "text": [ "the" ], "offsets": [ [ 91, 94 ] ], "normalized": [] }, { "id": "13607", "type": "0", "text": [ "defect" ], "offsets": [ [ 98, 104 ] ], "normalized": [] }, { "id": "13608", "type": "0", "text": [ "in" ], "offsets": [ [ 101, 103 ] ], "normalized": [] }, { "id": "13609", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 106, 110 ] ], "normalized": [] }, { "id": "13610", "type": "0", "text": [ "production" ], "offsets": [ [ 117, 127 ] ], "normalized": [] }, { "id": "13611", "type": "0", "text": [ "from" ], "offsets": [ [ 122, 126 ] ], "normalized": [] }, { "id": "13612", "type": "5", "text": [ "Ipr" ], "offsets": [ [ 126, 129 ] ], "normalized": [] }, { "id": "13613", "type": "6", "text": [ "CD4-8-" ], "offsets": [ [ 133, 139 ] ], "normalized": [] }, { "id": "13614", "type": "6", "text": [ "T" ], "offsets": [ [ 135, 136 ] ], "normalized": [] }, { "id": "13615", "type": "6", "text": [ "cells" ], "offsets": [ [ 141, 146 ] ], "normalized": [] }, { "id": "13616", "type": "0", "text": [ "." ], "offsets": [ [ 143, 144 ] ], "normalized": [] } ]
[]
[]
[]
13617
NULL
[]
[ { "id": "13618", "type": "0", "text": [ "Cross-linking" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "13619", "type": "0", "text": [ "of" ], "offsets": [ [ 17, 19 ] ], "normalized": [] }, { "id": "13620", "type": "9", "text": [ "CD30" ], "offsets": [ [ 22, 26 ] ], "normalized": [] }, { "id": "13621", "type": "0", "text": [ "induces" ], "offsets": [ [ 30, 37 ] ], "normalized": [] }, { "id": "13622", "type": "0", "text": [ "HIV" ], "offsets": [ [ 34, 37 ] ], "normalized": [] }, { "id": "13623", "type": "0", "text": [ "expression" ], "offsets": [ [ 45, 55 ] ], "normalized": [] }, { "id": "13624", "type": "0", "text": [ "in" ], "offsets": [ [ 48, 50 ] ], "normalized": [] }, { "id": "13625", "type": "0", "text": [ "chronically" ], "offsets": [ [ 60, 71 ] ], "normalized": [] }, { "id": "13626", "type": "0", "text": [ "infected" ], "offsets": [ [ 69, 77 ] ], "normalized": [] }, { "id": "13627", "type": "7", "text": [ "T" ], "offsets": [ [ 71, 72 ] ], "normalized": [] }, { "id": "13628", "type": "8", "text": [ "cells" ], "offsets": [ [ 77, 82 ] ], "normalized": [] }, { "id": "13629", "type": "0", "text": [ "." ], "offsets": [ [ 79, 80 ] ], "normalized": [] } ]
[]
[]
[]
13630
NULL
[]
[ { "id": "13631", "type": "9", "text": [ "CD30" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13632", "type": "0", "text": [ "," ], "offsets": [ [ 7, 8 ] ], "normalized": [] }, { "id": "13633", "type": "0", "text": [ "a" ], "offsets": [ [ 9, 10 ] ], "normalized": [] }, { "id": "13634", "type": "0", "text": [ "member" ], "offsets": [ [ 16, 22 ] ], "normalized": [] }, { "id": "13635", "type": "0", "text": [ "of" ], "offsets": [ [ 19, 21 ] ], "normalized": [] }, { "id": "13636", "type": "0", "text": [ "the" ], "offsets": [ [ 23, 26 ] ], "normalized": [] }, { "id": "13637", "type": "0", "text": [ "tumor" ], "offsets": [ [ 29, 34 ] ], "normalized": [] }, { "id": "13638", "type": "0", "text": [ "necrosis" ], "offsets": [ [ 38, 46 ] ], "normalized": [] }, { "id": "13639", "type": "0", "text": [ "factor" ], "offsets": [ [ 45, 51 ] ], "normalized": [] }, { "id": "13640", "type": "0", "text": [ "(" ], "offsets": [ [ 47, 48 ] ], "normalized": [] }, { "id": "13641", "type": "0", "text": [ "TNF" ], "offsets": [ [ 51, 54 ] ], "normalized": [] }, { "id": "13642", "type": "0", "text": [ ")" ], "offsets": [ [ 53, 54 ] ], "normalized": [] }, { "id": "13643", "type": "0", "text": [ "receptor" ], "offsets": [ [ 62, 70 ] ], "normalized": [] }, { "id": "13644", "type": "0", "text": [ "family" ], "offsets": [ [ 69, 75 ] ], "normalized": [] }, { "id": "13645", "type": "0", "text": [ "," ], "offsets": [ [ 71, 72 ] ], "normalized": [] }, { "id": "13646", "type": "0", "text": [ "is" ], "offsets": [ [ 74, 76 ] ], "normalized": [] }, { "id": "13647", "type": "0", "text": [ "expressed" ], "offsets": [ [ 84, 93 ] ], "normalized": [] }, { "id": "13648", "type": "0", "text": [ "constitutively" ], "offsets": [ [ 99, 113 ] ], "normalized": [] }, { "id": "13649", "type": "0", "text": [ "on" ], "offsets": [ [ 102, 104 ] ], "normalized": [] }, { "id": "13650", "type": "0", "text": [ "the" ], "offsets": [ [ 106, 109 ] ], "normalized": [] }, { "id": "13651", "type": "0", "text": [ "surface" ], "offsets": [ [ 114, 121 ] ], "normalized": [] }, { "id": "13652", "type": "0", "text": [ "of" ], "offsets": [ [ 117, 119 ] ], "normalized": [] }, { "id": "13653", "type": "0", "text": [ "the" ], "offsets": [ [ 121, 124 ] ], "normalized": [] }, { "id": "13654", "type": "0", "text": [ "human" ], "offsets": [ [ 127, 132 ] ], "normalized": [] }, { "id": "13655", "type": "0", "text": [ "T" ], "offsets": [ [ 129, 130 ] ], "normalized": [] }, { "id": "13656", "type": "0", "text": [ "cell" ], "offsets": [ [ 134, 138 ] ], "normalized": [] }, { "id": "13657", "type": "0", "text": [ "line" ], "offsets": [ [ 139, 143 ] ], "normalized": [] }, { "id": "13658", "type": "0", "text": [ "ACH-2" ], "offsets": [ [ 145, 150 ] ], "normalized": [] }, { "id": "13659", "type": "0", "text": [ "," ], "offsets": [ [ 147, 148 ] ], "normalized": [] }, { "id": "13660", "type": "0", "text": [ "which" ], "offsets": [ [ 153, 158 ] ], "normalized": [] }, { "id": "13661", "type": "0", "text": [ "is" ], "offsets": [ [ 156, 158 ] ], "normalized": [] }, { "id": "13662", "type": "0", "text": [ "chronically" ], "offsets": [ [ 168, 179 ] ], "normalized": [] }, { "id": "13663", "type": "0", "text": [ "infected" ], "offsets": [ [ 177, 185 ] ], "normalized": [] }, { "id": "13664", "type": "0", "text": [ "with" ], "offsets": [ [ 182, 186 ] ], "normalized": [] }, { "id": "13665", "type": "0", "text": [ "human" ], "offsets": [ [ 188, 193 ] ], "normalized": [] }, { "id": "13666", "type": "0", "text": [ "immunodeficiency" ], "offsets": [ [ 205, 221 ] ], "normalized": [] }, { "id": "13667", "type": "0", "text": [ "virus" ], "offsets": [ [ 211, 216 ] ], "normalized": [] }, { "id": "13668", "type": "0", "text": [ "type-1" ], "offsets": [ [ 218, 224 ] ], "normalized": [] }, { "id": "13669", "type": "0", "text": [ "(" ], "offsets": [ [ 220, 221 ] ], "normalized": [] }, { "id": "13670", "type": "0", "text": [ "HIV" ], "offsets": [ [ 224, 227 ] ], "normalized": [] }, { "id": "13671", "type": "0", "text": [ ")" ], "offsets": [ [ 226, 227 ] ], "normalized": [] }, { "id": "13672", "type": "0", "text": [ "-1" ], "offsets": [ [ 229, 231 ] ], "normalized": [] }, { "id": "13673", "type": "0", "text": [ "." ], "offsets": [ [ 231, 232 ] ], "normalized": [] } ]
[]
[]
[]
13674
NULL
[]
[ { "id": "13675", "type": "0", "text": [ "We" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "13676", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 15, 26 ] ], "normalized": [] }, { "id": "13677", "type": "0", "text": [ "that" ], "offsets": [ [ 20, 24 ] ], "normalized": [] }, { "id": "13678", "type": "0", "text": [ "cross-linking" ], "offsets": [ [ 34, 47 ] ], "normalized": [] }, { "id": "13679", "type": "9", "text": [ "CD30" ], "offsets": [ [ 39, 43 ] ], "normalized": [] }, { "id": "13680", "type": "0", "text": [ "with" ], "offsets": [ [ 44, 48 ] ], "normalized": [] }, { "id": "13681", "type": "0", "text": [ "an" ], "offsets": [ [ 47, 49 ] ], "normalized": [] }, { "id": "13682", "type": "0", "text": [ "anti-" ], "offsets": [ [ 53, 58 ] ], "normalized": [] }, { "id": "13683", "type": "9", "text": [ "CD30" ], "offsets": [ [ 58, 62 ] ], "normalized": [] }, { "id": "13684", "type": "0", "text": [ "-specific" ], "offsets": [ [ 68, 77 ] ], "normalized": [] }, { "id": "13685", "type": "0", "text": [ "monoclonal" ], "offsets": [ [ 79, 89 ] ], "normalized": [] }, { "id": "13686", "type": "0", "text": [ "antibody" ], "offsets": [ [ 88, 96 ] ], "normalized": [] }, { "id": "13687", "type": "0", "text": [ "," ], "offsets": [ [ 90, 91 ] ], "normalized": [] }, { "id": "13688", "type": "0", "text": [ "which" ], "offsets": [ [ 96, 101 ] ], "normalized": [] }, { "id": "13689", "type": "0", "text": [ "mimics" ], "offsets": [ [ 103, 109 ] ], "normalized": [] }, { "id": "13690", "type": "0", "text": [ "the" ], "offsets": [ [ 107, 110 ] ], "normalized": [] }, { "id": "13691", "type": "0", "text": [ "described" ], "offsets": [ [ 117, 126 ] ], "normalized": [] }, { "id": "13692", "type": "0", "text": [ "biological" ], "offsets": [ [ 128, 138 ] ], "normalized": [] }, { "id": "13693", "type": "0", "text": [ "activities" ], "offsets": [ [ 139, 149 ] ], "normalized": [] }, { "id": "13694", "type": "0", "text": [ "of" ], "offsets": [ [ 142, 144 ] ], "normalized": [] }, { "id": "13695", "type": "0", "text": [ "the" ], "offsets": [ [ 146, 149 ] ], "normalized": [] }, { "id": "13696", "type": "9", "text": [ "CD30" ], "offsets": [ [ 151, 155 ] ], "normalized": [] }, { "id": "13697", "type": "10", "text": [ "ligand" ], "offsets": [ [ 158, 164 ] ], "normalized": [] }, { "id": "13698", "type": "0", "text": [ "(" ], "offsets": [ [ 160, 161 ] ], "normalized": [] }, { "id": "13699", "type": "9", "text": [ "CD30L" ], "offsets": [ [ 166, 171 ] ], "normalized": [] }, { "id": "13700", "type": "0", "text": [ ")" ], "offsets": [ [ 168, 169 ] ], "normalized": [] }, { "id": "13701", "type": "0", "text": [ "," ], "offsets": [ [ 170, 171 ] ], "normalized": [] }, { "id": "13702", "type": "0", "text": [ "results" ], "offsets": [ [ 178, 185 ] ], "normalized": [] }, { "id": "13703", "type": "0", "text": [ "in" ], "offsets": [ [ 181, 183 ] ], "normalized": [] }, { "id": "13704", "type": "0", "text": [ "HIV" ], "offsets": [ [ 185, 188 ] ], "normalized": [] }, { "id": "13705", "type": "0", "text": [ "expression" ], "offsets": [ [ 196, 206 ] ], "normalized": [] }, { "id": "13706", "type": "0", "text": [ "." ], "offsets": [ [ 198, 199 ] ], "normalized": [] } ]
[]
[]
[]
13707
NULL
[]
[ { "id": "13708", "type": "9", "text": [ "CD30" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13709", "type": "0", "text": [ "cross-linking" ], "offsets": [ [ 19, 32 ] ], "normalized": [] }, { "id": "13710", "type": "0", "text": [ "does" ], "offsets": [ [ 24, 28 ] ], "normalized": [] }, { "id": "13711", "type": "0", "text": [ "not" ], "offsets": [ [ 28, 31 ] ], "normalized": [] }, { "id": "13712", "type": "0", "text": [ "alter" ], "offsets": [ [ 34, 39 ] ], "normalized": [] }, { "id": "13713", "type": "0", "text": [ "proliferation" ], "offsets": [ [ 48, 61 ] ], "normalized": [] }, { "id": "13714", "type": "0", "text": [ "of" ], "offsets": [ [ 51, 53 ] ], "normalized": [] }, { "id": "13715", "type": "5", "text": [ "ACH-2" ], "offsets": [ [ 57, 62 ] ], "normalized": [] }, { "id": "13716", "type": "6", "text": [ "cells" ], "offsets": [ [ 63, 68 ] ], "normalized": [] }, { "id": "13717", "type": "0", "text": [ "and" ], "offsets": [ [ 67, 70 ] ], "normalized": [] }, { "id": "13718", "type": "0", "text": [ "the" ], "offsets": [ [ 71, 74 ] ], "normalized": [] }, { "id": "13719", "type": "0", "text": [ "induction" ], "offsets": [ [ 81, 90 ] ], "normalized": [] }, { "id": "13720", "type": "0", "text": [ "of" ], "offsets": [ [ 84, 86 ] ], "normalized": [] }, { "id": "13721", "type": "0", "text": [ "HIV" ], "offsets": [ [ 88, 91 ] ], "normalized": [] }, { "id": "13722", "type": "0", "text": [ "expression" ], "offsets": [ [ 99, 109 ] ], "normalized": [] }, { "id": "13723", "type": "0", "text": [ "is" ], "offsets": [ [ 102, 104 ] ], "normalized": [] }, { "id": "13724", "type": "0", "text": [ "not" ], "offsets": [ [ 106, 109 ] ], "normalized": [] }, { "id": "13725", "type": "0", "text": [ "mediated" ], "offsets": [ [ 115, 123 ] ], "normalized": [] }, { "id": "13726", "type": "0", "text": [ "by" ], "offsets": [ [ 118, 120 ] ], "normalized": [] }, { "id": "13727", "type": "0", "text": [ "endogenous" ], "offsets": [ [ 129, 139 ] ], "normalized": [] }, { "id": "13728", "type": "9", "text": [ "TNF" ], "offsets": [ [ 133, 136 ] ], "normalized": [] }, { "id": "13729", "type": "10", "text": [ "alpha/beta" ], "offsets": [ [ 144, 154 ] ], "normalized": [] }, { "id": "13730", "type": "0", "text": [ "." ], "offsets": [ [ 146, 147 ] ], "normalized": [] } ]
[]
[]
[]
13731
NULL
[]
[ { "id": "13732", "type": "0", "text": [ "Furthermore" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "13733", "type": "0", "text": [ "," ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "13734", "type": "0", "text": [ "cross-linking" ], "offsets": [ [ 28, 41 ] ], "normalized": [] }, { "id": "13735", "type": "0", "text": [ "of" ], "offsets": [ [ 31, 33 ] ], "normalized": [] }, { "id": "13736", "type": "9", "text": [ "CD30" ], "offsets": [ [ 36, 40 ] ], "normalized": [] }, { "id": "13737", "type": "0", "text": [ "leads" ], "offsets": [ [ 42, 47 ] ], "normalized": [] }, { "id": "13738", "type": "0", "text": [ "to" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "13739", "type": "9", "text": [ "NF-kappa" ], "offsets": [ [ 54, 62 ] ], "normalized": [] }, { "id": "13740", "type": "10", "text": [ "B" ], "offsets": [ [ 56, 57 ] ], "normalized": [] }, { "id": "13741", "type": "0", "text": [ "activation" ], "offsets": [ [ 67, 77 ] ], "normalized": [] }, { "id": "13742", "type": "0", "text": [ "and" ], "offsets": [ [ 71, 74 ] ], "normalized": [] }, { "id": "13743", "type": "0", "text": [ "enhanced" ], "offsets": [ [ 80, 88 ] ], "normalized": [] }, { "id": "13744", "type": "0", "text": [ "HIV" ], "offsets": [ [ 84, 87 ] ], "normalized": [] }, { "id": "13745", "type": "0", "text": [ "transcription" ], "offsets": [ [ 98, 111 ] ], "normalized": [] }, { "id": "13746", "type": "0", "text": [ "." ], "offsets": [ [ 100, 101 ] ], "normalized": [] } ]
[]
[]
[]
13747
NULL
[]
[ { "id": "13748", "type": "0", "text": [ "Thus" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13749", "type": "0", "text": [ "," ], "offsets": [ [ 7, 8 ] ], "normalized": [] }, { "id": "13750", "type": "9", "text": [ "CD30" ], "offsets": [ [ 12, 16 ] ], "normalized": [] }, { "id": "13751", "type": "9", "text": [ "-CD30L" ], "offsets": [ [ 19, 25 ] ], "normalized": [] }, { "id": "13752", "type": "0", "text": [ "interactions" ], "offsets": [ [ 32, 44 ] ], "normalized": [] }, { "id": "13753", "type": "0", "text": [ "mediate" ], "offsets": [ [ 40, 47 ] ], "normalized": [] }, { "id": "13754", "type": "0", "text": [ "the" ], "offsets": [ [ 44, 47 ] ], "normalized": [] }, { "id": "13755", "type": "0", "text": [ "induction" ], "offsets": [ [ 54, 63 ] ], "normalized": [] }, { "id": "13756", "type": "0", "text": [ "of" ], "offsets": [ [ 57, 59 ] ], "normalized": [] }, { "id": "13757", "type": "0", "text": [ "HIV" ], "offsets": [ [ 61, 64 ] ], "normalized": [] }, { "id": "13758", "type": "0", "text": [ "expression" ], "offsets": [ [ 72, 82 ] ], "normalized": [] }, { "id": "13759", "type": "0", "text": [ "by" ], "offsets": [ [ 75, 77 ] ], "normalized": [] }, { "id": "13760", "type": "0", "text": [ "a" ], "offsets": [ [ 77, 78 ] ], "normalized": [] }, { "id": "13761", "type": "0", "text": [ "kappa" ], "offsets": [ [ 83, 88 ] ], "normalized": [] }, { "id": "13762", "type": "0", "text": [ "B-dependent" ], "offsets": [ [ 95, 106 ] ], "normalized": [] }, { "id": "13763", "type": "0", "text": [ "pathway" ], "offsets": [ [ 103, 110 ] ], "normalized": [] }, { "id": "13764", "type": "0", "text": [ "that" ], "offsets": [ [ 108, 112 ] ], "normalized": [] }, { "id": "13765", "type": "0", "text": [ "is" ], "offsets": [ [ 111, 113 ] ], "normalized": [] }, { "id": "13766", "type": "0", "text": [ "independent" ], "offsets": [ [ 123, 134 ] ], "normalized": [] }, { "id": "13767", "type": "0", "text": [ "of" ], "offsets": [ [ 126, 128 ] ], "normalized": [] }, { "id": "13768", "type": "9", "text": [ "TNF" ], "offsets": [ [ 130, 133 ] ], "normalized": [] }, { "id": "13769", "type": "0", "text": [ "." ], "offsets": [ [ 132, 133 ] ], "normalized": [] } ]
[]
[]
[]
13770
NULL
[]
[ { "id": "13771", "type": "0", "text": [ "This" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13772", "type": "0", "text": [ "mechanism" ], "offsets": [ [ 15, 24 ] ], "normalized": [] }, { "id": "13773", "type": "0", "text": [ "may" ], "offsets": [ [ 19, 22 ] ], "normalized": [] }, { "id": "13774", "type": "0", "text": [ "be" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "13775", "type": "0", "text": [ "important" ], "offsets": [ [ 32, 41 ] ], "normalized": [] }, { "id": "13776", "type": "0", "text": [ "in" ], "offsets": [ [ 35, 37 ] ], "normalized": [] }, { "id": "13777", "type": "0", "text": [ "the" ], "offsets": [ [ 39, 42 ] ], "normalized": [] }, { "id": "13778", "type": "0", "text": [ "activation" ], "offsets": [ [ 50, 60 ] ], "normalized": [] }, { "id": "13779", "type": "0", "text": [ "of" ], "offsets": [ [ 53, 55 ] ], "normalized": [] }, { "id": "13780", "type": "0", "text": [ "HIV" ], "offsets": [ [ 57, 60 ] ], "normalized": [] }, { "id": "13781", "type": "0", "text": [ "expression" ], "offsets": [ [ 68, 78 ] ], "normalized": [] }, { "id": "13782", "type": "0", "text": [ "from" ], "offsets": [ [ 73, 77 ] ], "normalized": [] }, { "id": "13783", "type": "0", "text": [ "latently" ], "offsets": [ [ 82, 90 ] ], "normalized": [] }, { "id": "13784", "type": "0", "text": [ "infected" ], "offsets": [ [ 91, 99 ] ], "normalized": [] }, { "id": "13785", "type": "5", "text": [ "CD4+" ], "offsets": [ [ 96, 100 ] ], "normalized": [] }, { "id": "13786", "type": "6", "text": [ "T" ], "offsets": [ [ 98, 99 ] ], "normalized": [] }, { "id": "13787", "type": "6", "text": [ "cells" ], "offsets": [ [ 104, 109 ] ], "normalized": [] }, { "id": "13788", "type": "0", "text": [ "," ], "offsets": [ [ 106, 107 ] ], "normalized": [] }, { "id": "13789", "type": "0", "text": [ "especially" ], "offsets": [ [ 117, 127 ] ], "normalized": [] }, { "id": "13790", "type": "0", "text": [ "in" ], "offsets": [ [ 120, 122 ] ], "normalized": [] }, { "id": "13791", "type": "0", "text": [ "lymphoid" ], "offsets": [ [ 129, 137 ] ], "normalized": [] }, { "id": "13792", "type": "0", "text": [ "organs" ], "offsets": [ [ 136, 142 ] ], "normalized": [] }, { "id": "13793", "type": "0", "text": [ "where" ], "offsets": [ [ 142, 147 ] ], "normalized": [] }, { "id": "13794", "type": "0", "text": [ "cell" ], "offsets": [ [ 147, 151 ] ], "normalized": [] }, { "id": "13795", "type": "0", "text": [ "to" ], "offsets": [ [ 150, 152 ] ], "normalized": [] }, { "id": "13796", "type": "0", "text": [ "cell" ], "offsets": [ [ 155, 159 ] ], "normalized": [] }, { "id": "13797", "type": "0", "text": [ "contact" ], "offsets": [ [ 163, 170 ] ], "normalized": [] }, { "id": "13798", "type": "0", "text": [ "is" ], "offsets": [ [ 166, 168 ] ], "normalized": [] }, { "id": "13799", "type": "0", "text": [ "conducive" ], "offsets": [ [ 176, 185 ] ], "normalized": [] }, { "id": "13800", "type": "0", "text": [ "to" ], "offsets": [ [ 179, 181 ] ], "normalized": [] }, { "id": "13801", "type": "0", "text": [ "receptor-ligand" ], "offsets": [ [ 195, 210 ] ], "normalized": [] }, { "id": "13802", "type": "0", "text": [ "interactions" ], "offsets": [ [ 208, 220 ] ], "normalized": [] }, { "id": "13803", "type": "0", "text": [ "." ], "offsets": [ [ 210, 211 ] ], "normalized": [] } ]
[]
[]
[]
13804
NULL
[]
[ { "id": "13805", "type": "0", "text": [ "Human" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "13806", "type": "1", "text": [ "MHC" ], "offsets": [ [ 10, 13 ] ], "normalized": [] }, { "id": "13807", "type": "2", "text": [ "class" ], "offsets": [ [ 16, 21 ] ], "normalized": [] }, { "id": "13808", "type": "2", "text": [ "II" ], "offsets": [ [ 19, 21 ] ], "normalized": [] }, { "id": "13809", "type": "2", "text": [ "gene" ], "offsets": [ [ 24, 28 ] ], "normalized": [] }, { "id": "13810", "type": "0", "text": [ "transcription" ], "offsets": [ [ 38, 51 ] ], "normalized": [] }, { "id": "13811", "type": "0", "text": [ "directed" ], "offsets": [ [ 47, 55 ] ], "normalized": [] }, { "id": "13812", "type": "0", "text": [ "by" ], "offsets": [ [ 50, 52 ] ], "normalized": [] }, { "id": "13813", "type": "0", "text": [ "the" ], "offsets": [ [ 54, 57 ] ], "normalized": [] }, { "id": "13814", "type": "9", "text": [ "carboxyl" ], "offsets": [ [ 63, 71 ] ], "normalized": [] }, { "id": "13815", "type": "10", "text": [ "terminus" ], "offsets": [ [ 72, 80 ] ], "normalized": [] }, { "id": "13816", "type": "0", "text": [ "of" ], "offsets": [ [ 75, 77 ] ], "normalized": [] }, { "id": "13817", "type": "1", "text": [ "CIITA" ], "offsets": [ [ 81, 86 ] ], "normalized": [] }, { "id": "13818", "type": "0", "text": [ "," ], "offsets": [ [ 83, 84 ] ], "normalized": [] }, { "id": "13819", "type": "0", "text": [ "one" ], "offsets": [ [ 87, 90 ] ], "normalized": [] }, { "id": "13820", "type": "0", "text": [ "of" ], "offsets": [ [ 90, 92 ] ], "normalized": [] }, { "id": "13821", "type": "0", "text": [ "the" ], "offsets": [ [ 94, 97 ] ], "normalized": [] }, { "id": "13822", "type": "1", "text": [ "defective" ], "offsets": [ [ 104, 113 ] ], "normalized": [] }, { "id": "13823", "type": "2", "text": [ "genes" ], "offsets": [ [ 110, 115 ] ], "normalized": [] }, { "id": "13824", "type": "0", "text": [ "in" ], "offsets": [ [ 113, 115 ] ], "normalized": [] }, { "id": "13825", "type": "0", "text": [ "type" ], "offsets": [ [ 118, 122 ] ], "normalized": [] }, { "id": "13826", "type": "0", "text": [ "II" ], "offsets": [ [ 121, 123 ] ], "normalized": [] }, { "id": "13827", "type": "9", "text": [ "MHC" ], "offsets": [ [ 125, 128 ] ], "normalized": [] }, { "id": "13828", "type": "0", "text": [ "combined" ], "offsets": [ [ 134, 142 ] ], "normalized": [] }, { "id": "13829", "type": "0", "text": [ "immune" ], "offsets": [ [ 141, 147 ] ], "normalized": [] }, { "id": "13830", "type": "0", "text": [ "deficiency" ], "offsets": [ [ 152, 162 ] ], "normalized": [] }, { "id": "13831", "type": "0", "text": [ "." ], "offsets": [ [ 154, 155 ] ], "normalized": [] } ]
[]
[]
[]
13832
NULL
[]
[ { "id": "13833", "type": "9", "text": [ "Type" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13834", "type": "10", "text": [ "II" ], "offsets": [ [ 8, 10 ] ], "normalized": [] }, { "id": "13835", "type": "10", "text": [ "major" ], "offsets": [ [ 14, 19 ] ], "normalized": [] }, { "id": "13836", "type": "10", "text": [ "histocompatibility" ], "offsets": [ [ 33, 51 ] ], "normalized": [] }, { "id": "13837", "type": "10", "text": [ "complex" ], "offsets": [ [ 41, 48 ] ], "normalized": [] }, { "id": "13838", "type": "0", "text": [ "combined" ], "offsets": [ [ 50, 58 ] ], "normalized": [] }, { "id": "13839", "type": "0", "text": [ "immune" ], "offsets": [ [ 57, 63 ] ], "normalized": [] }, { "id": "13840", "type": "0", "text": [ "deficiency" ], "offsets": [ [ 68, 78 ] ], "normalized": [] }, { "id": "13841", "type": "0", "text": [ "(" ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "13842", "type": "0", "text": [ "type" ], "offsets": [ [ 75, 79 ] ], "normalized": [] }, { "id": "13843", "type": "0", "text": [ "II" ], "offsets": [ [ 78, 80 ] ], "normalized": [] }, { "id": "13844", "type": "9", "text": [ "MHC" ], "offsets": [ [ 82, 85 ] ], "normalized": [] }, { "id": "13845", "type": "0", "text": [ "CID" ], "offsets": [ [ 86, 89 ] ], "normalized": [] }, { "id": "13846", "type": "0", "text": [ "or" ], "offsets": [ [ 89, 91 ] ], "normalized": [] }, { "id": "13847", "type": "0", "text": [ "bare" ], "offsets": [ [ 94, 98 ] ], "normalized": [] }, { "id": "13848", "type": "0", "text": [ "lymphocyte" ], "offsets": [ [ 105, 115 ] ], "normalized": [] }, { "id": "13849", "type": "0", "text": [ "syndrome" ], "offsets": [ [ 114, 122 ] ], "normalized": [] }, { "id": "13850", "type": "0", "text": [ ")" ], "offsets": [ [ 116, 117 ] ], "normalized": [] }, { "id": "13851", "type": "0", "text": [ "is" ], "offsets": [ [ 119, 121 ] ], "normalized": [] }, { "id": "13852", "type": "0", "text": [ "a" ], "offsets": [ [ 121, 122 ] ], "normalized": [] }, { "id": "13853", "type": "0", "text": [ "congenital" ], "offsets": [ [ 132, 142 ] ], "normalized": [] }, { "id": "13854", "type": "0", "text": [ "immunodeficiency" ], "offsets": [ [ 149, 165 ] ], "normalized": [] }, { "id": "13855", "type": "0", "text": [ "disease" ], "offsets": [ [ 157, 164 ] ], "normalized": [] }, { "id": "13856", "type": "0", "text": [ "characterized" ], "offsets": [ [ 171, 184 ] ], "normalized": [] }, { "id": "13857", "type": "0", "text": [ "by" ], "offsets": [ [ 174, 176 ] ], "normalized": [] }, { "id": "13858", "type": "0", "text": [ "absent" ], "offsets": [ [ 181, 187 ] ], "normalized": [] }, { "id": "13859", "type": "9", "text": [ "MHC" ], "offsets": [ [ 185, 188 ] ], "normalized": [] }, { "id": "13860", "type": "10", "text": [ "class" ], "offsets": [ [ 191, 196 ] ], "normalized": [] }, { "id": "13861", "type": "10", "text": [ "II" ], "offsets": [ [ 194, 196 ] ], "normalized": [] }, { "id": "13862", "type": "0", "text": [ "expression" ], "offsets": [ [ 205, 215 ] ], "normalized": [] }, { "id": "13863", "type": "0", "text": [ "." ], "offsets": [ [ 207, 208 ] ], "normalized": [] } ]
[]
[]
[]
13864
NULL
[]
[ { "id": "13865", "type": "0", "text": [ "Four" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13866", "type": "0", "text": [ "distinct" ], "offsets": [ [ 14, 22 ] ], "normalized": [] }, { "id": "13867", "type": "0", "text": [ "complementation" ], "offsets": [ [ 30, 45 ] ], "normalized": [] }, { "id": "13868", "type": "0", "text": [ "groups" ], "offsets": [ [ 37, 43 ] ], "normalized": [] }, { "id": "13869", "type": "0", "text": [ "have" ], "offsets": [ [ 42, 46 ] ], "normalized": [] }, { "id": "13870", "type": "0", "text": [ "been" ], "offsets": [ [ 47, 51 ] ], "normalized": [] }, { "id": "13871", "type": "0", "text": [ "identified" ], "offsets": [ [ 58, 68 ] ], "normalized": [] }, { "id": "13872", "type": "0", "text": [ "." ], "offsets": [ [ 60, 61 ] ], "normalized": [] } ]
[]
[]
[]
13873
NULL
[]
[ { "id": "13874", "type": "0", "text": [ "Recently" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "13875", "type": "0", "text": [ "," ], "offsets": [ [ 11, 12 ] ], "normalized": [] }, { "id": "13876", "type": "0", "text": [ "the" ], "offsets": [ [ 15, 18 ] ], "normalized": [] }, { "id": "13877", "type": "1", "text": [ "defective" ], "offsets": [ [ 25, 34 ] ], "normalized": [] }, { "id": "13878", "type": "2", "text": [ "gene" ], "offsets": [ [ 30, 34 ] ], "normalized": [] }, { "id": "13879", "type": "0", "text": [ "in" ], "offsets": [ [ 33, 35 ] ], "normalized": [] }, { "id": "13880", "type": "0", "text": [ "group" ], "offsets": [ [ 39, 44 ] ], "normalized": [] }, { "id": "13881", "type": "0", "text": [ "II" ], "offsets": [ [ 42, 44 ] ], "normalized": [] }, { "id": "13882", "type": "0", "text": [ "type" ], "offsets": [ [ 47, 51 ] ], "normalized": [] }, { "id": "13883", "type": "0", "text": [ "II" ], "offsets": [ [ 50, 52 ] ], "normalized": [] }, { "id": "13884", "type": "9", "text": [ "MHC" ], "offsets": [ [ 54, 57 ] ], "normalized": [] }, { "id": "13885", "type": "0", "text": [ "CID" ], "offsets": [ [ 58, 61 ] ], "normalized": [] }, { "id": "13886", "type": "0", "text": [ "has" ], "offsets": [ [ 62, 65 ] ], "normalized": [] }, { "id": "13887", "type": "0", "text": [ "been" ], "offsets": [ [ 67, 71 ] ], "normalized": [] }, { "id": "13888", "type": "0", "text": [ "isolated" ], "offsets": [ [ 76, 84 ] ], "normalized": [] }, { "id": "13889", "type": "0", "text": [ "and" ], "offsets": [ [ 80, 83 ] ], "normalized": [] }, { "id": "13890", "type": "0", "text": [ "termed" ], "offsets": [ [ 87, 93 ] ], "normalized": [] }, { "id": "13891", "type": "1", "text": [ "CIITA" ], "offsets": [ [ 93, 98 ] ], "normalized": [] }, { "id": "13892", "type": "0", "text": [ "." ], "offsets": [ [ 95, 96 ] ], "normalized": [] } ]
[]
[]
[]
13893
NULL
[]
[ { "id": "13894", "type": "0", "text": [ "Here" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "13895", "type": "0", "text": [ "," ], "offsets": [ [ 7, 8 ] ], "normalized": [] }, { "id": "13896", "type": "0", "text": [ "we" ], "offsets": [ [ 10, 12 ] ], "normalized": [] }, { "id": "13897", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 22, 33 ] ], "normalized": [] }, { "id": "13898", "type": "0", "text": [ "that" ], "offsets": [ [ 27, 31 ] ], "normalized": [] }, { "id": "13899", "type": "1", "text": [ "CIITA" ], "offsets": [ [ 33, 38 ] ], "normalized": [] }, { "id": "13900", "type": "0", "text": [ "is" ], "offsets": [ [ 36, 38 ] ], "normalized": [] }, { "id": "13901", "type": "0", "text": [ "an" ], "offsets": [ [ 39, 41 ] ], "normalized": [] }, { "id": "13902", "type": "1", "text": [ "MHC" ], "offsets": [ [ 43, 46 ] ], "normalized": [] }, { "id": "13903", "type": "2", "text": [ "class" ], "offsets": [ [ 49, 54 ] ], "normalized": [] }, { "id": "13904", "type": "2", "text": [ "II" ], "offsets": [ [ 52, 54 ] ], "normalized": [] }, { "id": "13905", "type": "2", "text": [ "gene-specific" ], "offsets": [ [ 66, 79 ] ], "normalized": [] }, { "id": "13906", "type": "2", "text": [ "transcription" ], "offsets": [ [ 80, 93 ] ], "normalized": [] }, { "id": "13907", "type": "2", "text": [ "activator" ], "offsets": [ [ 90, 99 ] ], "normalized": [] }, { "id": "13908", "type": "0", "text": [ "." ], "offsets": [ [ 92, 93 ] ], "normalized": [] } ]
[]
[]
[]
13909
NULL
[]
[ { "id": "13910", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "13911", "type": "0", "text": [ "transcription" ], "offsets": [ [ 18, 31 ] ], "normalized": [] }, { "id": "13912", "type": "0", "text": [ "activation" ], "offsets": [ [ 29, 39 ] ], "normalized": [] }, { "id": "13913", "type": "0", "text": [ "function" ], "offsets": [ [ 38, 46 ] ], "normalized": [] }, { "id": "13914", "type": "0", "text": [ "is" ], "offsets": [ [ 41, 43 ] ], "normalized": [] }, { "id": "13915", "type": "0", "text": [ "provided" ], "offsets": [ [ 50, 58 ] ], "normalized": [] }, { "id": "13916", "type": "0", "text": [ "by" ], "offsets": [ [ 53, 55 ] ], "normalized": [] }, { "id": "13917", "type": "0", "text": [ "the" ], "offsets": [ [ 57, 60 ] ], "normalized": [] }, { "id": "13918", "type": "9", "text": [ "N-terminal" ], "offsets": [ [ 68, 78 ] ], "normalized": [] }, { "id": "13919", "type": "10", "text": [ "acidic" ], "offsets": [ [ 75, 81 ] ], "normalized": [] }, { "id": "13920", "type": "10", "text": [ "domain" ], "offsets": [ [ 82, 88 ] ], "normalized": [] }, { "id": "13921", "type": "0", "text": [ "(" ], "offsets": [ [ 84, 85 ] ], "normalized": [] }, { "id": "13922", "type": "9", "text": [ "amino" ], "offsets": [ [ 90, 95 ] ], "normalized": [] }, { "id": "13923", "type": "10", "text": [ "acids" ], "offsets": [ [ 96, 101 ] ], "normalized": [] }, { "id": "13924", "type": "10", "text": [ "26-137" ], "offsets": [ [ 103, 109 ] ], "normalized": [] }, { "id": "13925", "type": "0", "text": [ ")" ], "offsets": [ [ 105, 106 ] ], "normalized": [] }, { "id": "13926", "type": "0", "text": [ "," ], "offsets": [ [ 107, 108 ] ], "normalized": [] }, { "id": "13927", "type": "0", "text": [ "which" ], "offsets": [ [ 113, 118 ] ], "normalized": [] }, { "id": "13928", "type": "0", "text": [ "is" ], "offsets": [ [ 116, 118 ] ], "normalized": [] }, { "id": "13929", "type": "0", "text": [ "experimentally" ], "offsets": [ [ 131, 145 ] ], "normalized": [] }, { "id": "13930", "type": "0", "text": [ "exchangeable" ], "offsets": [ [ 144, 156 ] ], "normalized": [] }, { "id": "13931", "type": "0", "text": [ "with" ], "offsets": [ [ 149, 153 ] ], "normalized": [] }, { "id": "13932", "type": "0", "text": [ "a" ], "offsets": [ [ 151, 152 ] ], "normalized": [] }, { "id": "13933", "type": "9", "text": [ "heterologous" ], "offsets": [ [ 164, 176 ] ], "normalized": [] }, { "id": "13934", "type": "10", "text": [ "viral" ], "offsets": [ [ 170, 175 ] ], "normalized": [] }, { "id": "13935", "type": "10", "text": [ "transcription-activating" ], "offsets": [ [ 195, 219 ] ], "normalized": [] }, { "id": "13936", "type": "10", "text": [ "domain" ], "offsets": [ [ 202, 208 ] ], "normalized": [] }, { "id": "13937", "type": "0", "text": [ "." ], "offsets": [ [ 204, 205 ] ], "normalized": [] } ]
[]
[]
[]
13938
NULL
[]
[ { "id": "13939", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "13940", "type": "0", "text": [ "specificity" ], "offsets": [ [ 16, 27 ] ], "normalized": [] }, { "id": "13941", "type": "0", "text": [ "of" ], "offsets": [ [ 19, 21 ] ], "normalized": [] }, { "id": "13942", "type": "9", "text": [ "CIITA" ], "offsets": [ [ 25, 30 ] ], "normalized": [] }, { "id": "13943", "type": "0", "text": [ "for" ], "offsets": [ [ 29, 32 ] ], "normalized": [] }, { "id": "13944", "type": "0", "text": [ "three" ], "offsets": [ [ 35, 40 ] ], "normalized": [] }, { "id": "13945", "type": "0", "text": [ "major" ], "offsets": [ [ 41, 46 ] ], "normalized": [] }, { "id": "13946", "type": "1", "text": [ "MHC" ], "offsets": [ [ 45, 48 ] ], "normalized": [] }, { "id": "13947", "type": "2", "text": [ "class" ], "offsets": [ [ 51, 56 ] ], "normalized": [] }, { "id": "13948", "type": "2", "text": [ "II" ], "offsets": [ [ 54, 56 ] ], "normalized": [] }, { "id": "13949", "type": "2", "text": [ "genes" ], "offsets": [ [ 60, 65 ] ], "normalized": [] }, { "id": "13950", "type": "0", "text": [ "," ], "offsets": [ [ 62, 63 ] ], "normalized": [] }, { "id": "13951", "type": "1", "text": [ "DR" ], "offsets": [ [ 65, 67 ] ], "normalized": [] }, { "id": "13952", "type": "0", "text": [ "," ], "offsets": [ [ 67, 68 ] ], "normalized": [] }, { "id": "13953", "type": "1", "text": [ "DQ" ], "offsets": [ [ 70, 72 ] ], "normalized": [] }, { "id": "13954", "type": "0", "text": [ "and" ], "offsets": [ [ 74, 77 ] ], "normalized": [] }, { "id": "13955", "type": "1", "text": [ "DP" ], "offsets": [ [ 77, 79 ] ], "normalized": [] }, { "id": "13956", "type": "0", "text": [ "," ], "offsets": [ [ 79, 80 ] ], "normalized": [] }, { "id": "13957", "type": "0", "text": [ "is" ], "offsets": [ [ 82, 84 ] ], "normalized": [] }, { "id": "13958", "type": "0", "text": [ "mediated" ], "offsets": [ [ 91, 99 ] ], "normalized": [] }, { "id": "13959", "type": "0", "text": [ "by" ], "offsets": [ [ 94, 96 ] ], "normalized": [] }, { "id": "13960", "type": "0", "text": [ "its" ], "offsets": [ [ 98, 101 ] ], "normalized": [] }, { "id": "13961", "type": "0", "text": [ "remaining" ], "offsets": [ [ 108, 117 ] ], "normalized": [] }, { "id": "13962", "type": "9", "text": [ "C-terminal" ], "offsets": [ [ 119, 129 ] ], "normalized": [] }, { "id": "13963", "type": "10", "text": [ "residues" ], "offsets": [ [ 128, 136 ] ], "normalized": [] }, { "id": "13964", "type": "0", "text": [ "(" ], "offsets": [ [ 130, 131 ] ], "normalized": [] }, { "id": "13965", "type": "9", "text": [ "amino" ], "offsets": [ [ 136, 141 ] ], "normalized": [] }, { "id": "13966", "type": "10", "text": [ "acids" ], "offsets": [ [ 142, 147 ] ], "normalized": [] }, { "id": "13967", "type": "10", "text": [ "317-1130" ], "offsets": [ [ 151, 159 ] ], "normalized": [] }, { "id": "13968", "type": "0", "text": [ ")" ], "offsets": [ [ 153, 154 ] ], "normalized": [] }, { "id": "13969", "type": "0", "text": [ "." ], "offsets": [ [ 155, 156 ] ], "normalized": [] } ]
[]
[]
[]
13970
NULL
[]
[ { "id": "13971", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "13972", "type": "0", "text": [ "transactivation" ], "offsets": [ [ 20, 35 ] ], "normalized": [] }, { "id": "13973", "type": "0", "text": [ "of" ], "offsets": [ [ 23, 25 ] ], "normalized": [] }, { "id": "13974", "type": "1", "text": [ "multiple" ], "offsets": [ [ 32, 40 ] ], "normalized": [] }, { "id": "13975", "type": "2", "text": [ "cis" ], "offsets": [ [ 36, 39 ] ], "normalized": [] }, { "id": "13976", "type": "2", "text": [ "elements" ], "offsets": [ [ 45, 53 ] ], "normalized": [] }, { "id": "13977", "type": "0", "text": [ "," ], "offsets": [ [ 47, 48 ] ], "normalized": [] }, { "id": "13978", "type": "0", "text": [ "especially" ], "offsets": [ [ 58, 68 ] ], "normalized": [] }, { "id": "13979", "type": "1", "text": [ "S" ], "offsets": [ [ 60, 61 ] ], "normalized": [] }, { "id": "13980", "type": "0", "text": [ "and" ], "offsets": [ [ 64, 67 ] ], "normalized": [] }, { "id": "13981", "type": "1", "text": [ "X2" ], "offsets": [ [ 67, 69 ] ], "normalized": [] }, { "id": "13982", "type": "0", "text": [ "," ], "offsets": [ [ 69, 70 ] ], "normalized": [] }, { "id": "13983", "type": "0", "text": [ "of" ], "offsets": [ [ 72, 74 ] ], "normalized": [] }, { "id": "13984", "type": "0", "text": [ "the" ], "offsets": [ [ 76, 79 ] ], "normalized": [] }, { "id": "13985", "type": "1", "text": [ "DR" ], "offsets": [ [ 79, 81 ] ], "normalized": [] }, { "id": "13986", "type": "2", "text": [ "alpha" ], "offsets": [ [ 85, 90 ] ], "normalized": [] }, { "id": "13987", "type": "2", "text": [ "proximal" ], "offsets": [ [ 94, 102 ] ], "normalized": [] }, { "id": "13988", "type": "2", "text": [ "promoter" ], "offsets": [ [ 103, 111 ] ], "normalized": [] }, { "id": "13989", "type": "0", "text": [ "in" ], "offsets": [ [ 106, 108 ] ], "normalized": [] }, { "id": "13990", "type": "5", "text": [ "group" ], "offsets": [ [ 112, 117 ] ], "normalized": [] }, { "id": "13991", "type": "6", "text": [ "II" ], "offsets": [ [ 115, 117 ] ], "normalized": [] }, { "id": "13992", "type": "6", "text": [ "CID" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "13993", "type": "6", "text": [ "cells" ], "offsets": [ [ 125, 130 ] ], "normalized": [] }, { "id": "13994", "type": "0", "text": [ "is" ], "offsets": [ [ 128, 130 ] ], "normalized": [] }, { "id": "13995", "type": "9", "text": [ "CIITA" ], "offsets": [ [ 134, 139 ] ], "normalized": [] }, { "id": "13996", "type": "0", "text": [ "dependent" ], "offsets": [ [ 144, 153 ] ], "normalized": [] }, { "id": "13997", "type": "0", "text": [ "." ], "offsets": [ [ 146, 147 ] ], "normalized": [] } ]
[]
[]
[]
13998
NULL
[]
[ { "id": "13999", "type": "0", "text": [ "Since" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14000", "type": "9", "text": [ "CIITA" ], "offsets": [ [ 12, 17 ] ], "normalized": [] }, { "id": "14001", "type": "0", "text": [ "overexpression" ], "offsets": [ [ 27, 41 ] ], "normalized": [] }, { "id": "14002", "type": "0", "text": [ "in" ], "offsets": [ [ 30, 32 ] ], "normalized": [] }, { "id": "14003", "type": "7", "text": [ "normal" ], "offsets": [ [ 37, 43 ] ], "normalized": [] }, { "id": "14004", "type": "8", "text": [ "cells" ], "offsets": [ [ 43, 48 ] ], "normalized": [] }, { "id": "14005", "type": "0", "text": [ "did" ], "offsets": [ [ 47, 50 ] ], "normalized": [] }, { "id": "14006", "type": "0", "text": [ "not" ], "offsets": [ [ 51, 54 ] ], "normalized": [] }, { "id": "14007", "type": "0", "text": [ "increase" ], "offsets": [ [ 60, 68 ] ], "normalized": [] }, { "id": "14008", "type": "0", "text": [ "class" ], "offsets": [ [ 66, 71 ] ], "normalized": [] }, { "id": "14009", "type": "0", "text": [ "II" ], "offsets": [ [ 69, 71 ] ], "normalized": [] }, { "id": "14010", "type": "0", "text": [ "expression" ], "offsets": [ [ 80, 90 ] ], "normalized": [] }, { "id": "14011", "type": "0", "text": [ "," ], "offsets": [ [ 82, 83 ] ], "normalized": [] }, { "id": "14012", "type": "0", "text": [ "we" ], "offsets": [ [ 85, 87 ] ], "normalized": [] }, { "id": "14013", "type": "0", "text": [ "propose" ], "offsets": [ [ 93, 100 ] ], "normalized": [] }, { "id": "14014", "type": "0", "text": [ "that" ], "offsets": [ [ 98, 102 ] ], "normalized": [] }, { "id": "14015", "type": "0", "text": [ "initiation" ], "offsets": [ [ 109, 119 ] ], "normalized": [] }, { "id": "14016", "type": "0", "text": [ "of" ], "offsets": [ [ 112, 114 ] ], "normalized": [] }, { "id": "14017", "type": "9", "text": [ "CIITA" ], "offsets": [ [ 118, 123 ] ], "normalized": [] }, { "id": "14018", "type": "0", "text": [ "expression" ], "offsets": [ [ 129, 139 ] ], "normalized": [] }, { "id": "14019", "type": "0", "text": [ "serves" ], "offsets": [ [ 136, 142 ] ], "normalized": [] }, { "id": "14020", "type": "0", "text": [ "as" ], "offsets": [ [ 139, 141 ] ], "normalized": [] }, { "id": "14021", "type": "0", "text": [ "the" ], "offsets": [ [ 143, 146 ] ], "normalized": [] }, { "id": "14022", "type": "0", "text": [ "on-off" ], "offsets": [ [ 150, 156 ] ], "normalized": [] }, { "id": "14023", "type": "0", "text": [ "switch" ], "offsets": [ [ 157, 163 ] ], "normalized": [] }, { "id": "14024", "type": "0", "text": [ "," ], "offsets": [ [ 159, 160 ] ], "normalized": [] }, { "id": "14025", "type": "0", "text": [ "while" ], "offsets": [ [ 165, 170 ] ], "normalized": [] }, { "id": "14026", "type": "0", "text": [ "availability" ], "offsets": [ [ 178, 190 ] ], "normalized": [] }, { "id": "14027", "type": "0", "text": [ "of" ], "offsets": [ [ 181, 183 ] ], "normalized": [] }, { "id": "14028", "type": "0", "text": [ "downstream" ], "offsets": [ [ 192, 202 ] ], "normalized": [] }, { "id": "14029", "type": "0", "text": [ "interactor" ], "offsets": [ [ 203, 213 ] ], "normalized": [] }, { "id": "14030", "type": "0", "text": [ "(" ], "offsets": [ [ 205, 206 ] ], "normalized": [] }, { "id": "14031", "type": "0", "text": [ "s" ], "offsets": [ [ 207, 208 ] ], "normalized": [] }, { "id": "14032", "type": "0", "text": [ ")" ], "offsets": [ [ 209, 210 ] ], "normalized": [] }, { "id": "14033", "type": "0", "text": [ "limits" ], "offsets": [ [ 216, 222 ] ], "normalized": [] }, { "id": "14034", "type": "0", "text": [ "transcription" ], "offsets": [ [ 230, 243 ] ], "normalized": [] }, { "id": "14035", "type": "0", "text": [ "." ], "offsets": [ [ 232, 233 ] ], "normalized": [] } ]
[]
[]
[]
14036
NULL
[]
[ { "id": "14037", "type": "0", "text": [ "Monocyte" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14038", "type": "0", "text": [ "tethering" ], "offsets": [ [ 19, 28 ] ], "normalized": [] }, { "id": "14039", "type": "0", "text": [ "by" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "14040", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 33, 43 ] ], "normalized": [] }, { "id": "14041", "type": "0", "text": [ "regulates" ], "offsets": [ [ 43, 52 ] ], "normalized": [] }, { "id": "14042", "type": "9", "text": [ "monocyte" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "14043", "type": "10", "text": [ "chemotactic" ], "offsets": [ [ 64, 75 ] ], "normalized": [] }, { "id": "14044", "type": "10", "text": [ "protein-1" ], "offsets": [ [ 74, 83 ] ], "normalized": [] }, { "id": "14045", "type": "0", "text": [ "and" ], "offsets": [ [ 78, 81 ] ], "normalized": [] }, { "id": "14046", "type": "9", "text": [ "tumor" ], "offsets": [ [ 84, 89 ] ], "normalized": [] }, { "id": "14047", "type": "10", "text": [ "necrosis" ], "offsets": [ [ 93, 101 ] ], "normalized": [] }, { "id": "14048", "type": "10", "text": [ "factor-alpha" ], "offsets": [ [ 106, 118 ] ], "normalized": [] }, { "id": "14049", "type": "0", "text": [ "secretion" ], "offsets": [ [ 116, 125 ] ], "normalized": [] }, { "id": "14050", "type": "0", "text": [ "." ], "offsets": [ [ 118, 119 ] ], "normalized": [] } ]
[]
[]
[]
14051
NULL
[]
[ { "id": "14052", "type": "0", "text": [ "Signal" ], "offsets": [ [ 7, 13 ] ], "normalized": [] }, { "id": "14053", "type": "0", "text": [ "integration" ], "offsets": [ [ 19, 30 ] ], "normalized": [] }, { "id": "14054", "type": "0", "text": [ "and" ], "offsets": [ [ 23, 26 ] ], "normalized": [] }, { "id": "14055", "type": "9", "text": [ "NF-kappa" ], "offsets": [ [ 32, 40 ] ], "normalized": [] }, { "id": "14056", "type": "10", "text": [ "B" ], "offsets": [ [ 34, 35 ] ], "normalized": [] }, { "id": "14057", "type": "0", "text": [ "translocation" ], "offsets": [ [ 48, 61 ] ], "normalized": [] }, { "id": "14058", "type": "0", "text": [ "[" ], "offsets": [ [ 50, 51 ] ], "normalized": [] }, { "id": "14059", "type": "0", "text": [ "see" ], "offsets": [ [ 54, 57 ] ], "normalized": [] }, { "id": "14060", "type": "0", "text": [ "comments" ], "offsets": [ [ 63, 71 ] ], "normalized": [] }, { "id": "14061", "type": "0", "text": [ "]" ], "offsets": [ [ 65, 66 ] ], "normalized": [] } ]
[]
[]
[]
14062
NULL
[]
[ { "id": "14063", "type": "9", "text": [ "Adhesion" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14064", "type": "10", "text": [ "molecules" ], "offsets": [ [ 19, 28 ] ], "normalized": [] }, { "id": "14065", "type": "0", "text": [ "that" ], "offsets": [ [ 24, 28 ] ], "normalized": [] }, { "id": "14066", "type": "0", "text": [ "tether" ], "offsets": [ [ 31, 37 ] ], "normalized": [] }, { "id": "14067", "type": "7", "text": [ "circulating" ], "offsets": [ [ 43, 54 ] ], "normalized": [] }, { "id": "14068", "type": "8", "text": [ "leukocytes" ], "offsets": [ [ 54, 64 ] ], "normalized": [] }, { "id": "14069", "type": "0", "text": [ "to" ], "offsets": [ [ 57, 59 ] ], "normalized": [] }, { "id": "14070", "type": "7", "text": [ "endothelial" ], "offsets": [ [ 69, 80 ] ], "normalized": [] }, { "id": "14071", "type": "8", "text": [ "cells" ], "offsets": [ [ 75, 80 ] ], "normalized": [] }, { "id": "14072", "type": "0", "text": [ "may" ], "offsets": [ [ 79, 82 ] ], "normalized": [] }, { "id": "14073", "type": "0", "text": [ "also" ], "offsets": [ [ 84, 88 ] ], "normalized": [] }, { "id": "14074", "type": "0", "text": [ "transduce" ], "offsets": [ [ 94, 103 ] ], "normalized": [] }, { "id": "14075", "type": "0", "text": [ "or" ], "offsets": [ [ 97, 99 ] ], "normalized": [] }, { "id": "14076", "type": "0", "text": [ "modulate" ], "offsets": [ [ 106, 114 ] ], "normalized": [] }, { "id": "14077", "type": "0", "text": [ "outside-in" ], "offsets": [ [ 117, 127 ] ], "normalized": [] }, { "id": "14078", "type": "0", "text": [ "signals" ], "offsets": [ [ 125, 132 ] ], "normalized": [] }, { "id": "14079", "type": "0", "text": [ "for" ], "offsets": [ [ 129, 132 ] ], "normalized": [] }, { "id": "14080", "type": "0", "text": [ "cellular" ], "offsets": [ [ 138, 146 ] ], "normalized": [] }, { "id": "14081", "type": "0", "text": [ "activation" ], "offsets": [ [ 149, 159 ] ], "normalized": [] }, { "id": "14082", "type": "0", "text": [ "," ], "offsets": [ [ 151, 152 ] ], "normalized": [] }, { "id": "14083", "type": "0", "text": [ "providing" ], "offsets": [ [ 161, 170 ] ], "normalized": [] }, { "id": "14084", "type": "0", "text": [ "an" ], "offsets": [ [ 164, 166 ] ], "normalized": [] }, { "id": "14085", "type": "0", "text": [ "initial" ], "offsets": [ [ 172, 179 ] ], "normalized": [] }, { "id": "14086", "type": "0", "text": [ "regulatory" ], "offsets": [ [ 183, 193 ] ], "normalized": [] }, { "id": "14087", "type": "0", "text": [ "point" ], "offsets": [ [ 189, 194 ] ], "normalized": [] }, { "id": "14088", "type": "0", "text": [ "in" ], "offsets": [ [ 192, 194 ] ], "normalized": [] }, { "id": "14089", "type": "0", "text": [ "the" ], "offsets": [ [ 196, 199 ] ], "normalized": [] }, { "id": "14090", "type": "0", "text": [ "inflammatory" ], "offsets": [ [ 209, 221 ] ], "normalized": [] }, { "id": "14091", "type": "0", "text": [ "response" ], "offsets": [ [ 218, 226 ] ], "normalized": [] }, { "id": "14092", "type": "0", "text": [ "." ], "offsets": [ [ 220, 221 ] ], "normalized": [] } ]
[]
[]
[]
14093
NULL
[]
[ { "id": "14094", "type": "0", "text": [ "Adhesion" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14095", "type": "0", "text": [ "of" ], "offsets": [ [ 12, 14 ] ], "normalized": [] }, { "id": "14096", "type": "7", "text": [ "human" ], "offsets": [ [ 18, 23 ] ], "normalized": [] }, { "id": "14097", "type": "8", "text": [ "monocytes" ], "offsets": [ [ 28, 37 ] ], "normalized": [] }, { "id": "14098", "type": "0", "text": [ "to" ], "offsets": [ [ 31, 33 ] ], "normalized": [] }, { "id": "14099", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 42, 52 ] ], "normalized": [] }, { "id": "14100", "type": "0", "text": [ "," ], "offsets": [ [ 44, 45 ] ], "normalized": [] }, { "id": "14101", "type": "0", "text": [ "the" ], "offsets": [ [ 48, 51 ] ], "normalized": [] }, { "id": "14102", "type": "0", "text": [ "most" ], "offsets": [ [ 53, 57 ] ], "normalized": [] }, { "id": "14103", "type": "0", "text": [ "rapidly" ], "offsets": [ [ 61, 68 ] ], "normalized": [] }, { "id": "14104", "type": "0", "text": [ "expressed" ], "offsets": [ [ 71, 80 ] ], "normalized": [] }, { "id": "14105", "type": "9", "text": [ "endothelial" ], "offsets": [ [ 83, 94 ] ], "normalized": [] }, { "id": "14106", "type": "10", "text": [ "tethering" ], "offsets": [ [ 93, 102 ] ], "normalized": [] }, { "id": "14107", "type": "10", "text": [ "factor" ], "offsets": [ [ 100, 106 ] ], "normalized": [] }, { "id": "14108", "type": "0", "text": [ "," ], "offsets": [ [ 102, 103 ] ], "normalized": [] }, { "id": "14109", "type": "0", "text": [ "increased" ], "offsets": [ [ 112, 121 ] ], "normalized": [] }, { "id": "14110", "type": "0", "text": [ "the" ], "offsets": [ [ 116, 119 ] ], "normalized": [] }, { "id": "14111", "type": "0", "text": [ "secretion" ], "offsets": [ [ 126, 135 ] ], "normalized": [] }, { "id": "14112", "type": "0", "text": [ "of" ], "offsets": [ [ 129, 131 ] ], "normalized": [] }, { "id": "14113", "type": "9", "text": [ "monocyte" ], "offsets": [ [ 138, 146 ] ], "normalized": [] }, { "id": "14114", "type": "10", "text": [ "chemotactic" ], "offsets": [ [ 150, 161 ] ], "normalized": [] }, { "id": "14115", "type": "10", "text": [ "protein-1" ], "offsets": [ [ 160, 169 ] ], "normalized": [] }, { "id": "14116", "type": "0", "text": [ "(" ], "offsets": [ [ 162, 163 ] ], "normalized": [] }, { "id": "14117", "type": "9", "text": [ "MCP-1" ], "offsets": [ [ 168, 173 ] ], "normalized": [] }, { "id": "14118", "type": "0", "text": [ ")" ], "offsets": [ [ 170, 171 ] ], "normalized": [] }, { "id": "14119", "type": "0", "text": [ "and" ], "offsets": [ [ 174, 177 ] ], "normalized": [] }, { "id": "14120", "type": "9", "text": [ "tumor" ], "offsets": [ [ 180, 185 ] ], "normalized": [] }, { "id": "14121", "type": "10", "text": [ "necrosis" ], "offsets": [ [ 189, 197 ] ], "normalized": [] }, { "id": "14122", "type": "10", "text": [ "factor-alpha" ], "offsets": [ [ 202, 214 ] ], "normalized": [] }, { "id": "14123", "type": "0", "text": [ "(" ], "offsets": [ [ 204, 205 ] ], "normalized": [] }, { "id": "14124", "type": "9", "text": [ "TNF-alpha" ], "offsets": [ [ 214, 223 ] ], "normalized": [] }, { "id": "14125", "type": "0", "text": [ ")" ], "offsets": [ [ 216, 217 ] ], "normalized": [] }, { "id": "14126", "type": "0", "text": [ "by" ], "offsets": [ [ 219, 221 ] ], "normalized": [] }, { "id": "14127", "type": "0", "text": [ "the" ], "offsets": [ [ 223, 226 ] ], "normalized": [] }, { "id": "14128", "type": "7", "text": [ "leukocytes" ], "offsets": [ [ 234, 244 ] ], "normalized": [] }, { "id": "14129", "type": "0", "text": [ "when" ], "offsets": [ [ 239, 243 ] ], "normalized": [] }, { "id": "14130", "type": "0", "text": [ "they" ], "offsets": [ [ 244, 248 ] ], "normalized": [] }, { "id": "14131", "type": "0", "text": [ "were" ], "offsets": [ [ 249, 253 ] ], "normalized": [] }, { "id": "14132", "type": "0", "text": [ "stimulated" ], "offsets": [ [ 260, 270 ] ], "normalized": [] }, { "id": "14133", "type": "0", "text": [ "with" ], "offsets": [ [ 265, 269 ] ], "normalized": [] }, { "id": "14134", "type": "9", "text": [ "platelet-activating" ], "offsets": [ [ 285, 304 ] ], "normalized": [] }, { "id": "14135", "type": "10", "text": [ "factor" ], "offsets": [ [ 292, 298 ] ], "normalized": [] }, { "id": "14136", "type": "0", "text": [ "." ], "offsets": [ [ 294, 295 ] ], "normalized": [] } ]
[]
[]
[]
14137
NULL
[]
[ { "id": "14138", "type": "0", "text": [ "Increased" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "14139", "type": "0", "text": [ "cytokine" ], "offsets": [ [ 19, 27 ] ], "normalized": [] }, { "id": "14140", "type": "0", "text": [ "secretion" ], "offsets": [ [ 29, 38 ] ], "normalized": [] }, { "id": "14141", "type": "0", "text": [ "was" ], "offsets": [ [ 33, 36 ] ], "normalized": [] }, { "id": "14142", "type": "0", "text": [ "specifically" ], "offsets": [ [ 46, 58 ] ], "normalized": [] }, { "id": "14143", "type": "0", "text": [ "inhibited" ], "offsets": [ [ 56, 65 ] ], "normalized": [] }, { "id": "14144", "type": "0", "text": [ "by" ], "offsets": [ [ 59, 61 ] ], "normalized": [] }, { "id": "14145", "type": "9", "text": [ "G1" ], "offsets": [ [ 62, 64 ] ], "normalized": [] }, { "id": "14146", "type": "0", "text": [ "," ], "offsets": [ [ 64, 65 ] ], "normalized": [] }, { "id": "14147", "type": "0", "text": [ "an" ], "offsets": [ [ 67, 69 ] ], "normalized": [] }, { "id": "14148", "type": "9", "text": [ "anti-P-selectin" ], "offsets": [ [ 83, 98 ] ], "normalized": [] }, { "id": "14149", "type": "10", "text": [ "mAb" ], "offsets": [ [ 87, 90 ] ], "normalized": [] }, { "id": "14150", "type": "0", "text": [ "that" ], "offsets": [ [ 92, 96 ] ], "normalized": [] }, { "id": "14151", "type": "0", "text": [ "prevents" ], "offsets": [ [ 101, 109 ] ], "normalized": [] }, { "id": "14152", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 112, 122 ] ], "normalized": [] }, { "id": "14153", "type": "0", "text": [ "from" ], "offsets": [ [ 117, 121 ] ], "normalized": [] }, { "id": "14154", "type": "0", "text": [ "binding" ], "offsets": [ [ 125, 132 ] ], "normalized": [] }, { "id": "14155", "type": "0", "text": [ "to" ], "offsets": [ [ 128, 130 ] ], "normalized": [] }, { "id": "14156", "type": "0", "text": [ "its" ], "offsets": [ [ 132, 135 ] ], "normalized": [] }, { "id": "14157", "type": "0", "text": [ "ligand" ], "offsets": [ [ 139, 145 ] ], "normalized": [] }, { "id": "14158", "type": "0", "text": [ "(" ], "offsets": [ [ 141, 142 ] ], "normalized": [] }, { "id": "14159", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 152, 162 ] ], "normalized": [] }, { "id": "14160", "type": "10", "text": [ "glycoprotein" ], "offsets": [ [ 165, 177 ] ], "normalized": [] }, { "id": "14161", "type": "10", "text": [ "ligand-1" ], "offsets": [ [ 174, 182 ] ], "normalized": [] }, { "id": "14162", "type": "0", "text": [ ")" ], "offsets": [ [ 176, 177 ] ], "normalized": [] }, { "id": "14163", "type": "0", "text": [ "on" ], "offsets": [ [ 179, 181 ] ], "normalized": [] }, { "id": "14164", "type": "7", "text": [ "myeloid" ], "offsets": [ [ 187, 194 ] ], "normalized": [] }, { "id": "14165", "type": "8", "text": [ "cells" ], "offsets": [ [ 193, 198 ] ], "normalized": [] }, { "id": "14166", "type": "0", "text": [ "." ], "offsets": [ [ 195, 196 ] ], "normalized": [] } ]
[]
[]
[]
14167
NULL
[]
[ { "id": "14168", "type": "0", "text": [ "Moreover" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14169", "type": "0", "text": [ "," ], "offsets": [ [ 11, 12 ] ], "normalized": [] }, { "id": "14170", "type": "0", "text": [ "tethering" ], "offsets": [ [ 21, 30 ] ], "normalized": [] }, { "id": "14171", "type": "0", "text": [ "by" ], "offsets": [ [ 24, 26 ] ], "normalized": [] }, { "id": "14172", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 35, 45 ] ], "normalized": [] }, { "id": "14173", "type": "0", "text": [ "specifically" ], "offsets": [ [ 48, 60 ] ], "normalized": [] }, { "id": "14174", "type": "0", "text": [ "enhanced" ], "offsets": [ [ 57, 65 ] ], "normalized": [] }, { "id": "14175", "type": "0", "text": [ "nuclear" ], "offsets": [ [ 65, 72 ] ], "normalized": [] }, { "id": "14176", "type": "0", "text": [ "translocation" ], "offsets": [ [ 79, 92 ] ], "normalized": [] }, { "id": "14177", "type": "0", "text": [ "of" ], "offsets": [ [ 82, 84 ] ], "normalized": [] }, { "id": "14178", "type": "9", "text": [ "nuclear" ], "offsets": [ [ 90, 97 ] ], "normalized": [] }, { "id": "14179", "type": "10", "text": [ "factor-kappa" ], "offsets": [ [ 103, 115 ] ], "normalized": [] }, { "id": "14180", "type": "10", "text": [ "B" ], "offsets": [ [ 105, 106 ] ], "normalized": [] }, { "id": "14181", "type": "0", "text": [ "(" ], "offsets": [ [ 107, 108 ] ], "normalized": [] }, { "id": "14182", "type": "9", "text": [ "NF-kappa" ], "offsets": [ [ 116, 124 ] ], "normalized": [] }, { "id": "14183", "type": "10", "text": [ "B" ], "offsets": [ [ 118, 119 ] ], "normalized": [] }, { "id": "14184", "type": "0", "text": [ ")" ], "offsets": [ [ 120, 121 ] ], "normalized": [] }, { "id": "14185", "type": "0", "text": [ "," ], "offsets": [ [ 122, 123 ] ], "normalized": [] }, { "id": "14186", "type": "0", "text": [ "a" ], "offsets": [ [ 124, 125 ] ], "normalized": [] }, { "id": "14187", "type": "9", "text": [ "transcription" ], "offsets": [ [ 138, 151 ] ], "normalized": [] }, { "id": "14188", "type": "10", "text": [ "factor" ], "offsets": [ [ 145, 151 ] ], "normalized": [] }, { "id": "14189", "type": "0", "text": [ "required" ], "offsets": [ [ 154, 162 ] ], "normalized": [] }, { "id": "14190", "type": "0", "text": [ "for" ], "offsets": [ [ 158, 161 ] ], "normalized": [] }, { "id": "14191", "type": "0", "text": [ "expression" ], "offsets": [ [ 169, 179 ] ], "normalized": [] }, { "id": "14192", "type": "0", "text": [ "of" ], "offsets": [ [ 172, 174 ] ], "normalized": [] }, { "id": "14193", "type": "9", "text": [ "MCP-1" ], "offsets": [ [ 178, 183 ] ], "normalized": [] }, { "id": "14194", "type": "0", "text": [ "," ], "offsets": [ [ 180, 181 ] ], "normalized": [] }, { "id": "14195", "type": "9", "text": [ "TNF-alpha" ], "offsets": [ [ 190, 199 ] ], "normalized": [] }, { "id": "14196", "type": "0", "text": [ "," ], "offsets": [ [ 192, 193 ] ], "normalized": [] }, { "id": "14197", "type": "0", "text": [ "and" ], "offsets": [ [ 196, 199 ] ], "normalized": [] }, { "id": "14198", "type": "0", "text": [ "other" ], "offsets": [ [ 202, 207 ] ], "normalized": [] }, { "id": "14199", "type": "1", "text": [ "immediate-early" ], "offsets": [ [ 218, 233 ] ], "normalized": [] }, { "id": "14200", "type": "2", "text": [ "genes" ], "offsets": [ [ 224, 229 ] ], "normalized": [] }, { "id": "14201", "type": "0", "text": [ "." ], "offsets": [ [ 226, 227 ] ], "normalized": [] } ]
[]
[]
[]
14202
NULL
[]
[ { "id": "14203", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14204", "type": "0", "text": [ "results" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "14205", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 26, 37 ] ], "normalized": [] }, { "id": "14206", "type": "0", "text": [ "that" ], "offsets": [ [ 31, 35 ] ], "normalized": [] }, { "id": "14207", "type": "9", "text": [ "P-selectin" ], "offsets": [ [ 42, 52 ] ], "normalized": [] }, { "id": "14208", "type": "0", "text": [ "," ], "offsets": [ [ 44, 45 ] ], "normalized": [] }, { "id": "14209", "type": "0", "text": [ "through" ], "offsets": [ [ 52, 59 ] ], "normalized": [] }, { "id": "14210", "type": "0", "text": [ "its" ], "offsets": [ [ 56, 59 ] ], "normalized": [] }, { "id": "14211", "type": "0", "text": [ "ligands" ], "offsets": [ [ 64, 71 ] ], "normalized": [] }, { "id": "14212", "type": "0", "text": [ "on" ], "offsets": [ [ 67, 69 ] ], "normalized": [] }, { "id": "14213", "type": "7", "text": [ "monocytes" ], "offsets": [ [ 77, 86 ] ], "normalized": [] }, { "id": "14214", "type": "0", "text": [ "," ], "offsets": [ [ 79, 80 ] ], "normalized": [] }, { "id": "14215", "type": "0", "text": [ "may" ], "offsets": [ [ 83, 86 ] ], "normalized": [] }, { "id": "14216", "type": "0", "text": [ "locally" ], "offsets": [ [ 91, 98 ] ], "normalized": [] }, { "id": "14217", "type": "0", "text": [ "regulate" ], "offsets": [ [ 100, 108 ] ], "normalized": [] }, { "id": "14218", "type": "9", "text": [ "cytokine" ], "offsets": [ [ 109, 117 ] ], "normalized": [] }, { "id": "14219", "type": "0", "text": [ "secretion" ], "offsets": [ [ 119, 128 ] ], "normalized": [] }, { "id": "14220", "type": "0", "text": [ "in" ], "offsets": [ [ 122, 124 ] ], "normalized": [] }, { "id": "14221", "type": "0", "text": [ "inflamed" ], "offsets": [ [ 131, 139 ] ], "normalized": [] }, { "id": "14222", "type": "0", "text": [ "tissues" ], "offsets": [ [ 139, 146 ] ], "normalized": [] }, { "id": "14223", "type": "0", "text": [ "." ], "offsets": [ [ 141, 142 ] ], "normalized": [] } ]
[]
[]
[]
14224
NULL
[]
[ { "id": "14225", "type": "0", "text": [ "Functional" ], "offsets": [ [ 11, 21 ] ], "normalized": [] }, { "id": "14226", "type": "0", "text": [ "roles" ], "offsets": [ [ 17, 22 ] ], "normalized": [] }, { "id": "14227", "type": "0", "text": [ "of" ], "offsets": [ [ 20, 22 ] ], "normalized": [] }, { "id": "14228", "type": "1", "text": [ "in" ], "offsets": [ [ 23, 25 ] ], "normalized": [] }, { "id": "14229", "type": "2", "text": [ "vivo" ], "offsets": [ [ 28, 32 ] ], "normalized": [] }, { "id": "14230", "type": "2", "text": [ "footprinted" ], "offsets": [ [ 40, 51 ] ], "normalized": [] }, { "id": "14231", "type": "2", "text": [ "DNA" ], "offsets": [ [ 44, 47 ] ], "normalized": [] }, { "id": "14232", "type": "2", "text": [ "motifs" ], "offsets": [ [ 51, 57 ] ], "normalized": [] }, { "id": "14233", "type": "0", "text": [ "within" ], "offsets": [ [ 58, 64 ] ], "normalized": [] }, { "id": "14234", "type": "0", "text": [ "an" ], "offsets": [ [ 61, 63 ] ], "normalized": [] }, { "id": "14235", "type": "1", "text": [ "alpha-globin" ], "offsets": [ [ 74, 86 ] ], "normalized": [] }, { "id": "14236", "type": "2", "text": [ "enhancer" ], "offsets": [ [ 83, 91 ] ], "normalized": [] }, { "id": "14237", "type": "0", "text": [ "." ], "offsets": [ [ 85, 86 ] ], "normalized": [] } ]
[]
[]
[]
14238
NULL
[]
[ { "id": "14239", "type": "0", "text": [ "Erythroid" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "14240", "type": "0", "text": [ "lineage" ], "offsets": [ [ 18, 25 ] ], "normalized": [] }, { "id": "14241", "type": "0", "text": [ "and" ], "offsets": [ [ 22, 25 ] ], "normalized": [] }, { "id": "14242", "type": "0", "text": [ "developmental" ], "offsets": [ [ 36, 49 ] ], "normalized": [] }, { "id": "14243", "type": "0", "text": [ "stage" ], "offsets": [ [ 42, 47 ] ], "normalized": [] }, { "id": "14244", "type": "0", "text": [ "specificities" ], "offsets": [ [ 56, 69 ] ], "normalized": [] }, { "id": "14245", "type": "0", "text": [ "." ], "offsets": [ [ 58, 59 ] ], "normalized": [] } ]
[]
[]
[]
14246
NULL
[]
[ { "id": "14247", "type": "0", "text": [ "Transcriptional" ], "offsets": [ [ 16, 31 ] ], "normalized": [] }, { "id": "14248", "type": "0", "text": [ "regulation" ], "offsets": [ [ 27, 37 ] ], "normalized": [] }, { "id": "14249", "type": "0", "text": [ "of" ], "offsets": [ [ 30, 32 ] ], "normalized": [] }, { "id": "14250", "type": "0", "text": [ "the" ], "offsets": [ [ 34, 37 ] ], "normalized": [] }, { "id": "14251", "type": "1", "text": [ "human" ], "offsets": [ [ 40, 45 ] ], "normalized": [] }, { "id": "14252", "type": "2", "text": [ "alpha-like" ], "offsets": [ [ 51, 61 ] ], "normalized": [] }, { "id": "14253", "type": "2", "text": [ "globin" ], "offsets": [ [ 58, 64 ] ], "normalized": [] }, { "id": "14254", "type": "2", "text": [ "genes" ], "offsets": [ [ 64, 69 ] ], "normalized": [] }, { "id": "14255", "type": "0", "text": [ "," ], "offsets": [ [ 66, 67 ] ], "normalized": [] }, { "id": "14256", "type": "1", "text": [ "embryonic" ], "offsets": [ [ 76, 85 ] ], "normalized": [] }, { "id": "14257", "type": "2", "text": [ "zeta" ], "offsets": [ [ 81, 85 ] ], "normalized": [] }, { "id": "14258", "type": "2", "text": [ "2" ], "offsets": [ [ 83, 84 ] ], "normalized": [] }, { "id": "14259", "type": "0", "text": [ "and" ], "offsets": [ [ 87, 90 ] ], "normalized": [] }, { "id": "14260", "type": "1", "text": [ "adult" ], "offsets": [ [ 93, 98 ] ], "normalized": [] }, { "id": "14261", "type": "2", "text": [ "alpha" ], "offsets": [ [ 99, 104 ] ], "normalized": [] }, { "id": "14262", "type": "0", "text": [ "," ], "offsets": [ [ 101, 102 ] ], "normalized": [] }, { "id": "14263", "type": "0", "text": [ "during" ], "offsets": [ [ 108, 114 ] ], "normalized": [] }, { "id": "14264", "type": "0", "text": [ "erythroid" ], "offsets": [ [ 118, 127 ] ], "normalized": [] }, { "id": "14265", "type": "0", "text": [ "development" ], "offsets": [ [ 130, 141 ] ], "normalized": [] }, { "id": "14266", "type": "0", "text": [ "is" ], "offsets": [ [ 133, 135 ] ], "normalized": [] }, { "id": "14267", "type": "0", "text": [ "mediated" ], "offsets": [ [ 142, 150 ] ], "normalized": [] }, { "id": "14268", "type": "0", "text": [ "by" ], "offsets": [ [ 145, 147 ] ], "normalized": [] }, { "id": "14269", "type": "0", "text": [ "a" ], "offsets": [ [ 147, 148 ] ], "normalized": [] }, { "id": "14270", "type": "1", "text": [ "distal" ], "offsets": [ [ 154, 160 ] ], "normalized": [] }, { "id": "14271", "type": "2", "text": [ "enhancer" ], "offsets": [ [ 163, 171 ] ], "normalized": [] }, { "id": "14272", "type": "0", "text": [ "," ], "offsets": [ [ 165, 166 ] ], "normalized": [] }, { "id": "14273", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 171, 176 ] ], "normalized": [] }, { "id": "14274", "type": "0", "text": [ "." ], "offsets": [ [ 173, 174 ] ], "normalized": [] } ]
[]
[]
[]
14275
NULL
[]
[ { "id": "14276", "type": "0", "text": [ "Previous" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14277", "type": "0", "text": [ "protein-DNA" ], "offsets": [ [ 21, 32 ] ], "normalized": [] }, { "id": "14278", "type": "0", "text": [ "binding" ], "offsets": [ [ 29, 36 ] ], "normalized": [] }, { "id": "14279", "type": "0", "text": [ "studies" ], "offsets": [ [ 37, 44 ] ], "normalized": [] }, { "id": "14280", "type": "0", "text": [ "have" ], "offsets": [ [ 42, 46 ] ], "normalized": [] }, { "id": "14281", "type": "0", "text": [ "shown" ], "offsets": [ [ 48, 53 ] ], "normalized": [] }, { "id": "14282", "type": "0", "text": [ "that" ], "offsets": [ [ 53, 57 ] ], "normalized": [] }, { "id": "14283", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 59, 64 ] ], "normalized": [] }, { "id": "14284", "type": "0", "text": [ "consists" ], "offsets": [ [ 68, 76 ] ], "normalized": [] }, { "id": "14285", "type": "0", "text": [ "of" ], "offsets": [ [ 71, 73 ] ], "normalized": [] }, { "id": "14286", "type": "0", "text": [ "multiple" ], "offsets": [ [ 80, 88 ] ], "normalized": [] }, { "id": "14287", "type": "1", "text": [ "nuclear" ], "offsets": [ [ 88, 95 ] ], "normalized": [] }, { "id": "14288", "type": "2", "text": [ "factor" ], "offsets": [ [ 95, 101 ] ], "normalized": [] }, { "id": "14289", "type": "2", "text": [ "binding" ], "offsets": [ [ 103, 110 ] ], "normalized": [] }, { "id": "14290", "type": "2", "text": [ "motifs" ], "offsets": [ [ 110, 116 ] ], "normalized": [] }, { "id": "14291", "type": "0", "text": [ "that" ], "offsets": [ [ 115, 119 ] ], "normalized": [] }, { "id": "14292", "type": "0", "text": [ "are" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "14293", "type": "0", "text": [ "occupied" ], "offsets": [ [ 128, 136 ] ], "normalized": [] }, { "id": "14294", "type": "0", "text": [ "in" ], "offsets": [ [ 131, 133 ] ], "normalized": [] }, { "id": "14295", "type": "0", "text": [ "vivo" ], "offsets": [ [ 136, 140 ] ], "normalized": [] }, { "id": "14296", "type": "0", "text": [ "in" ], "offsets": [ [ 139, 141 ] ], "normalized": [] }, { "id": "14297", "type": "0", "text": [ "an" ], "offsets": [ [ 142, 144 ] ], "normalized": [] }, { "id": "14298", "type": "0", "text": [ "erythroid" ], "offsets": [ [ 152, 161 ] ], "normalized": [] }, { "id": "14299", "type": "0", "text": [ "lineage-" ], "offsets": [ [ 161, 169 ] ], "normalized": [] }, { "id": "14300", "type": "0", "text": [ "and" ], "offsets": [ [ 165, 168 ] ], "normalized": [] }, { "id": "14301", "type": "0", "text": [ "developmental" ], "offsets": [ [ 179, 192 ] ], "normalized": [] }, { "id": "14302", "type": "0", "text": [ "stage-specific" ], "offsets": [ [ 194, 208 ] ], "normalized": [] }, { "id": "14303", "type": "0", "text": [ "manner" ], "offsets": [ [ 201, 207 ] ], "normalized": [] }, { "id": "14304", "type": "0", "text": [ "." ], "offsets": [ [ 203, 204 ] ], "normalized": [] } ]
[]
[]
[]
14305
NULL
[]
[ { "id": "14306", "type": "0", "text": [ "We" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14307", "type": "0", "text": [ "have" ], "offsets": [ [ 8, 12 ] ], "normalized": [] }, { "id": "14308", "type": "0", "text": [ "systematically" ], "offsets": [ [ 23, 37 ] ], "normalized": [] }, { "id": "14309", "type": "0", "text": [ "analyzed" ], "offsets": [ [ 32, 40 ] ], "normalized": [] }, { "id": "14310", "type": "0", "text": [ "the" ], "offsets": [ [ 36, 39 ] ], "normalized": [] }, { "id": "14311", "type": "0", "text": [ "functional" ], "offsets": [ [ 47, 57 ] ], "normalized": [] }, { "id": "14312", "type": "0", "text": [ "roles" ], "offsets": [ [ 53, 58 ] ], "normalized": [] }, { "id": "14313", "type": "0", "text": [ "of" ], "offsets": [ [ 56, 58 ] ], "normalized": [] }, { "id": "14314", "type": "0", "text": [ "these" ], "offsets": [ [ 62, 67 ] ], "normalized": [] }, { "id": "14315", "type": "1", "text": [ "factor" ], "offsets": [ [ 69, 75 ] ], "normalized": [] }, { "id": "14316", "type": "2", "text": [ "binding" ], "offsets": [ [ 77, 84 ] ], "normalized": [] }, { "id": "14317", "type": "2", "text": [ "motifs" ], "offsets": [ [ 84, 90 ] ], "normalized": [] }, { "id": "14318", "type": "0", "text": [ "of" ], "offsets": [ [ 87, 89 ] ], "normalized": [] }, { "id": "14319", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 93, 98 ] ], "normalized": [] }, { "id": "14320", "type": "0", "text": [ "by" ], "offsets": [ [ 96, 98 ] ], "normalized": [] }, { "id": "14321", "type": "0", "text": [ "site-directed" ], "offsets": [ [ 110, 123 ] ], "normalized": [] }, { "id": "14322", "type": "0", "text": [ "mutagenesis" ], "offsets": [ [ 122, 133 ] ], "normalized": [] }, { "id": "14323", "type": "0", "text": [ "and" ], "offsets": [ [ 126, 129 ] ], "normalized": [] }, { "id": "14324", "type": "0", "text": [ "transient" ], "offsets": [ [ 136, 145 ] ], "normalized": [] }, { "id": "14325", "type": "0", "text": [ "expression" ], "offsets": [ [ 147, 157 ] ], "normalized": [] }, { "id": "14326", "type": "0", "text": [ "assay" ], "offsets": [ [ 153, 158 ] ], "normalized": [] }, { "id": "14327", "type": "0", "text": [ "in" ], "offsets": [ [ 156, 158 ] ], "normalized": [] }, { "id": "14328", "type": "5", "text": [ "erythroid" ], "offsets": [ [ 166, 175 ] ], "normalized": [] }, { "id": "14329", "type": "6", "text": [ "cell" ], "offsets": [ [ 171, 175 ] ], "normalized": [] }, { "id": "14330", "type": "6", "text": [ "cultures" ], "offsets": [ [ 180, 188 ] ], "normalized": [] }, { "id": "14331", "type": "0", "text": [ "." ], "offsets": [ [ 182, 183 ] ], "normalized": [] } ]
[]
[]
[]
14332
NULL
[]
[ { "id": "14333", "type": "0", "text": [ "Three" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14334", "type": "0", "text": [ "of" ], "offsets": [ [ 9, 11 ] ], "normalized": [] }, { "id": "14335", "type": "0", "text": [ "these" ], "offsets": [ [ 15, 20 ] ], "normalized": [] }, { "id": "14336", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 21, 26 ] ], "normalized": [] }, { "id": "14337", "type": "2", "text": [ "enhancer" ], "offsets": [ [ 30, 38 ] ], "normalized": [] }, { "id": "14338", "type": "2", "text": [ "motifs" ], "offsets": [ [ 37, 43 ] ], "normalized": [] }, { "id": "14339", "type": "0", "text": [ "," ], "offsets": [ [ 39, 40 ] ], "normalized": [] }, { "id": "14340", "type": "1", "text": [ "5'NF-E2/AP1" ], "offsets": [ [ 51, 62 ] ], "normalized": [] }, { "id": "14341", "type": "0", "text": [ "," ], "offsets": [ [ 53, 54 ] ], "normalized": [] }, { "id": "14342", "type": "1", "text": [ "GT" ], "offsets": [ [ 56, 58 ] ], "normalized": [] }, { "id": "14343", "type": "2", "text": [ "II" ], "offsets": [ [ 59, 61 ] ], "normalized": [] }, { "id": "14344", "type": "0", "text": [ "," ], "offsets": [ [ 61, 62 ] ], "normalized": [] }, { "id": "14345", "type": "0", "text": [ "and" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "14346", "type": "1", "text": [ "GATA-1" ], "offsets": [ [ 72, 78 ] ], "normalized": [] }, { "id": "14347", "type": "2", "text": [ "(" ], "offsets": [ [ 74, 75 ] ], "normalized": [] }, { "id": "14348", "type": "2", "text": [ "c" ], "offsets": [ [ 76, 77 ] ], "normalized": [] }, { "id": "14349", "type": "2", "text": [ ")" ], "offsets": [ [ 78, 79 ] ], "normalized": [] }, { "id": "14350", "type": "0", "text": [ "," ], "offsets": [ [ 80, 81 ] ], "normalized": [] }, { "id": "14351", "type": "0", "text": [ "positively" ], "offsets": [ [ 91, 101 ] ], "normalized": [] }, { "id": "14352", "type": "0", "text": [ "regulate" ], "offsets": [ [ 100, 108 ] ], "normalized": [] }, { "id": "14353", "type": "0", "text": [ "the" ], "offsets": [ [ 104, 107 ] ], "normalized": [] }, { "id": "14354", "type": "1", "text": [ "zeta" ], "offsets": [ [ 109, 113 ] ], "normalized": [] }, { "id": "14355", "type": "2", "text": [ "2-globin" ], "offsets": [ [ 118, 126 ] ], "normalized": [] }, { "id": "14356", "type": "2", "text": [ "promoter" ], "offsets": [ [ 127, 135 ] ], "normalized": [] }, { "id": "14357", "type": "0", "text": [ "activity" ], "offsets": [ [ 136, 144 ] ], "normalized": [] }, { "id": "14358", "type": "0", "text": [ "in" ], "offsets": [ [ 139, 141 ] ], "normalized": [] }, { "id": "14359", "type": "5", "text": [ "embryonic/fetal" ], "offsets": [ [ 155, 170 ] ], "normalized": [] }, { "id": "14360", "type": "6", "text": [ "erythroid" ], "offsets": [ [ 165, 174 ] ], "normalized": [] }, { "id": "14361", "type": "6", "text": [ "K562" ], "offsets": [ [ 170, 174 ] ], "normalized": [] }, { "id": "14362", "type": "6", "text": [ "cells" ], "offsets": [ [ 176, 181 ] ], "normalized": [] }, { "id": "14363", "type": "0", "text": [ "and" ], "offsets": [ [ 180, 183 ] ], "normalized": [] }, { "id": "14364", "type": "0", "text": [ "the" ], "offsets": [ [ 184, 187 ] ], "normalized": [] }, { "id": "14365", "type": "1", "text": [ "adult" ], "offsets": [ [ 190, 195 ] ], "normalized": [] }, { "id": "14366", "type": "2", "text": [ "alpha-globin" ], "offsets": [ [ 203, 215 ] ], "normalized": [] }, { "id": "14367", "type": "2", "text": [ "promoter" ], "offsets": [ [ 212, 220 ] ], "normalized": [] }, { "id": "14368", "type": "0", "text": [ "activity" ], "offsets": [ [ 221, 229 ] ], "normalized": [] }, { "id": "14369", "type": "0", "text": [ "in" ], "offsets": [ [ 224, 226 ] ], "normalized": [] }, { "id": "14370", "type": "5", "text": [ "adult" ], "offsets": [ [ 230, 235 ] ], "normalized": [] }, { "id": "14371", "type": "6", "text": [ "erythroid" ], "offsets": [ [ 240, 249 ] ], "normalized": [] }, { "id": "14372", "type": "6", "text": [ "MEL" ], "offsets": [ [ 244, 247 ] ], "normalized": [] }, { "id": "14373", "type": "6", "text": [ "cells" ], "offsets": [ [ 250, 255 ] ], "normalized": [] }, { "id": "14374", "type": "0", "text": [ "." ], "offsets": [ [ 252, 253 ] ], "normalized": [] } ]
[]
[]
[]
14375
NULL
[]
[ { "id": "14376", "type": "0", "text": [ "On" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14377", "type": "0", "text": [ "the" ], "offsets": [ [ 7, 10 ] ], "normalized": [] }, { "id": "14378", "type": "0", "text": [ "other" ], "offsets": [ [ 13, 18 ] ], "normalized": [] }, { "id": "14379", "type": "0", "text": [ "hand" ], "offsets": [ [ 18, 22 ] ], "normalized": [] }, { "id": "14380", "type": "0", "text": [ "," ], "offsets": [ [ 20, 21 ] ], "normalized": [] }, { "id": "14381", "type": "0", "text": [ "the" ], "offsets": [ [ 24, 27 ] ], "normalized": [] }, { "id": "14382", "type": "1", "text": [ "3'NF-E2/AP1" ], "offsets": [ [ 36, 47 ] ], "normalized": [] }, { "id": "14383", "type": "2", "text": [ "motif" ], "offsets": [ [ 42, 47 ] ], "normalized": [] }, { "id": "14384", "type": "0", "text": [ "is" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "14385", "type": "0", "text": [ "able" ], "offsets": [ [ 50, 54 ] ], "normalized": [] }, { "id": "14386", "type": "0", "text": [ "to" ], "offsets": [ [ 53, 55 ] ], "normalized": [] }, { "id": "14387", "type": "0", "text": [ "exert" ], "offsets": [ [ 59, 64 ] ], "normalized": [] }, { "id": "14388", "type": "0", "text": [ "both" ], "offsets": [ [ 64, 68 ] ], "normalized": [] }, { "id": "14389", "type": "0", "text": [ "positive" ], "offsets": [ [ 73, 81 ] ], "normalized": [] }, { "id": "14390", "type": "0", "text": [ "and" ], "offsets": [ [ 77, 80 ] ], "normalized": [] }, { "id": "14391", "type": "0", "text": [ "negative" ], "offsets": [ [ 86, 94 ] ], "normalized": [] }, { "id": "14392", "type": "0", "text": [ "regulatory" ], "offsets": [ [ 97, 107 ] ], "normalized": [] }, { "id": "14393", "type": "0", "text": [ "effects" ], "offsets": [ [ 105, 112 ] ], "normalized": [] }, { "id": "14394", "type": "0", "text": [ "on" ], "offsets": [ [ 108, 110 ] ], "normalized": [] }, { "id": "14395", "type": "0", "text": [ "the" ], "offsets": [ [ 112, 115 ] ], "normalized": [] }, { "id": "14396", "type": "1", "text": [ "zeta" ], "offsets": [ [ 117, 121 ] ], "normalized": [] }, { "id": "14397", "type": "2", "text": [ "2-globin" ], "offsets": [ [ 126, 134 ] ], "normalized": [] }, { "id": "14398", "type": "2", "text": [ "promoter" ], "offsets": [ [ 135, 143 ] ], "normalized": [] }, { "id": "14399", "type": "0", "text": [ "activity" ], "offsets": [ [ 144, 152 ] ], "normalized": [] }, { "id": "14400", "type": "0", "text": [ "in" ], "offsets": [ [ 147, 149 ] ], "normalized": [] }, { "id": "14401", "type": "5", "text": [ "K562" ], "offsets": [ [ 152, 156 ] ], "normalized": [] }, { "id": "14402", "type": "6", "text": [ "cells" ], "offsets": [ [ 158, 163 ] ], "normalized": [] }, { "id": "14403", "type": "0", "text": [ "," ], "offsets": [ [ 160, 161 ] ], "normalized": [] }, { "id": "14404", "type": "0", "text": [ "and" ], "offsets": [ [ 164, 167 ] ], "normalized": [] }, { "id": "14405", "type": "0", "text": [ "this" ], "offsets": [ [ 169, 173 ] ], "normalized": [] }, { "id": "14406", "type": "0", "text": [ "dual" ], "offsets": [ [ 174, 178 ] ], "normalized": [] }, { "id": "14407", "type": "0", "text": [ "function" ], "offsets": [ [ 183, 191 ] ], "normalized": [] }, { "id": "14408", "type": "0", "text": [ "appears" ], "offsets": [ [ 191, 198 ] ], "normalized": [] }, { "id": "14409", "type": "0", "text": [ "to" ], "offsets": [ [ 194, 196 ] ], "normalized": [] }, { "id": "14410", "type": "0", "text": [ "be" ], "offsets": [ [ 197, 199 ] ], "normalized": [] }, { "id": "14411", "type": "0", "text": [ "modulated" ], "offsets": [ [ 207, 216 ] ], "normalized": [] }, { "id": "14412", "type": "0", "text": [ "through" ], "offsets": [ [ 215, 222 ] ], "normalized": [] }, { "id": "14413", "type": "0", "text": [ "differential" ], "offsets": [ [ 228, 240 ] ], "normalized": [] }, { "id": "14414", "type": "0", "text": [ "binding" ], "offsets": [ [ 236, 243 ] ], "normalized": [] }, { "id": "14415", "type": "0", "text": [ "of" ], "offsets": [ [ 239, 241 ] ], "normalized": [] }, { "id": "14416", "type": "0", "text": [ "the" ], "offsets": [ [ 243, 246 ] ], "normalized": [] }, { "id": "14417", "type": "9", "text": [ "ubiquitous" ], "offsets": [ [ 254, 264 ] ], "normalized": [] }, { "id": "14418", "type": "10", "text": [ "AP1" ], "offsets": [ [ 258, 261 ] ], "normalized": [] }, { "id": "14419", "type": "10", "text": [ "factors" ], "offsets": [ [ 266, 273 ] ], "normalized": [] }, { "id": "14420", "type": "0", "text": [ "and" ], "offsets": [ [ 270, 273 ] ], "normalized": [] }, { "id": "14421", "type": "0", "text": [ "the" ], "offsets": [ [ 274, 277 ] ], "normalized": [] }, { "id": "14422", "type": "9", "text": [ "erythroid-enriched" ], "offsets": [ [ 293, 311 ] ], "normalized": [] }, { "id": "14423", "type": "10", "text": [ "NF-E2" ], "offsets": [ [ 299, 304 ] ], "normalized": [] }, { "id": "14424", "type": "10", "text": [ "factor" ], "offsets": [ [ 306, 312 ] ], "normalized": [] }, { "id": "14425", "type": "0", "text": [ "." ], "offsets": [ [ 308, 309 ] ], "normalized": [] } ]
[]
[]
[]
14426
NULL
[]
[ { "id": "14427", "type": "0", "text": [ "Mutation" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14428", "type": "0", "text": [ "in" ], "offsets": [ [ 12, 14 ] ], "normalized": [] }, { "id": "14429", "type": "0", "text": [ "the" ], "offsets": [ [ 16, 19 ] ], "normalized": [] }, { "id": "14430", "type": "1", "text": [ "GATA-1" ], "offsets": [ [ 23, 29 ] ], "normalized": [] }, { "id": "14431", "type": "2", "text": [ "(" ], "offsets": [ [ 25, 26 ] ], "normalized": [] }, { "id": "14432", "type": "2", "text": [ "d" ], "offsets": [ [ 27, 28 ] ], "normalized": [] }, { "id": "14433", "type": "2", "text": [ ")" ], "offsets": [ [ 29, 30 ] ], "normalized": [] }, { "id": "14434", "type": "2", "text": [ "motif" ], "offsets": [ [ 35, 40 ] ], "normalized": [] }, { "id": "14435", "type": "0", "text": [ "," ], "offsets": [ [ 37, 38 ] ], "normalized": [] }, { "id": "14436", "type": "0", "text": [ "which" ], "offsets": [ [ 43, 48 ] ], "normalized": [] }, { "id": "14437", "type": "0", "text": [ "exhibits" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "14438", "type": "0", "text": [ "an" ], "offsets": [ [ 55, 57 ] ], "normalized": [] }, { "id": "14439", "type": "1", "text": [ "adult" ], "offsets": [ [ 61, 66 ] ], "normalized": [] }, { "id": "14440", "type": "2", "text": [ "erythroid-specific" ], "offsets": [ [ 80, 98 ] ], "normalized": [] }, { "id": "14441", "type": "2", "text": [ "genomic" ], "offsets": [ [ 88, 95 ] ], "normalized": [] }, { "id": "14442", "type": "2", "text": [ "footprint" ], "offsets": [ [ 98, 107 ] ], "normalized": [] }, { "id": "14443", "type": "0", "text": [ "," ], "offsets": [ [ 100, 101 ] ], "normalized": [] }, { "id": "14444", "type": "0", "text": [ "decreases" ], "offsets": [ [ 110, 119 ] ], "normalized": [] }, { "id": "14445", "type": "0", "text": [ "the" ], "offsets": [ [ 114, 117 ] ], "normalized": [] }, { "id": "14446", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 120, 125 ] ], "normalized": [] }, { "id": "14447", "type": "2", "text": [ "enhancer" ], "offsets": [ [ 129, 137 ] ], "normalized": [] }, { "id": "14448", "type": "0", "text": [ "function" ], "offsets": [ [ 138, 146 ] ], "normalized": [] }, { "id": "14449", "type": "0", "text": [ "in" ], "offsets": [ [ 141, 143 ] ], "normalized": [] }, { "id": "14450", "type": "5", "text": [ "dimethyl" ], "offsets": [ [ 150, 158 ] ], "normalized": [] }, { "id": "14451", "type": "6", "text": [ "sulfoxide-induced" ], "offsets": [ [ 168, 185 ] ], "normalized": [] }, { "id": "14452", "type": "6", "text": [ "MEL" ], "offsets": [ [ 172, 175 ] ], "normalized": [] }, { "id": "14453", "type": "6", "text": [ "cells" ], "offsets": [ [ 178, 183 ] ], "normalized": [] }, { "id": "14454", "type": "0", "text": [ "but" ], "offsets": [ [ 182, 185 ] ], "normalized": [] }, { "id": "14455", "type": "0", "text": [ "not" ], "offsets": [ [ 186, 189 ] ], "normalized": [] }, { "id": "14456", "type": "0", "text": [ "in" ], "offsets": [ [ 189, 191 ] ], "normalized": [] }, { "id": "14457", "type": "5", "text": [ "K562" ], "offsets": [ [ 194, 198 ] ], "normalized": [] }, { "id": "14458", "type": "6", "text": [ "cells" ], "offsets": [ [ 200, 205 ] ], "normalized": [] }, { "id": "14459", "type": "0", "text": [ "." ], "offsets": [ [ 202, 203 ] ], "normalized": [] } ]
[]
[]
[]
14460
NULL
[]
[ { "id": "14461", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14462", "type": "0", "text": [ "studies" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "14463", "type": "0", "text": [ "have" ], "offsets": [ [ 19, 23 ] ], "normalized": [] }, { "id": "14464", "type": "0", "text": [ "defined" ], "offsets": [ [ 27, 34 ] ], "normalized": [] }, { "id": "14465", "type": "0", "text": [ "the" ], "offsets": [ [ 31, 34 ] ], "normalized": [] }, { "id": "14466", "type": "0", "text": [ "regulatory" ], "offsets": [ [ 42, 52 ] ], "normalized": [] }, { "id": "14467", "type": "0", "text": [ "roles" ], "offsets": [ [ 48, 53 ] ], "normalized": [] }, { "id": "14468", "type": "0", "text": [ "of" ], "offsets": [ [ 51, 53 ] ], "normalized": [] }, { "id": "14469", "type": "0", "text": [ "the" ], "offsets": [ [ 55, 58 ] ], "normalized": [] }, { "id": "14470", "type": "0", "text": [ "different" ], "offsets": [ [ 65, 74 ] ], "normalized": [] }, { "id": "14471", "type": "1", "text": [ "HS-40" ], "offsets": [ [ 71, 76 ] ], "normalized": [] }, { "id": "14472", "type": "2", "text": [ "motifs" ], "offsets": [ [ 78, 84 ] ], "normalized": [] }, { "id": "14473", "type": "0", "text": [ "." ], "offsets": [ [ 80, 81 ] ], "normalized": [] } ]
[]
[]
[]
14474
NULL
[]
[ { "id": "14475", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "14476", "type": "0", "text": [ "remarkable" ], "offsets": [ [ 15, 25 ] ], "normalized": [] }, { "id": "14477", "type": "0", "text": [ "correlation" ], "offsets": [ [ 27, 38 ] ], "normalized": [] }, { "id": "14478", "type": "0", "text": [ "between" ], "offsets": [ [ 35, 42 ] ], "normalized": [] }, { "id": "14479", "type": "0", "text": [ "genomic" ], "offsets": [ [ 43, 50 ] ], "normalized": [] }, { "id": "14480", "type": "0", "text": [ "footprinting" ], "offsets": [ [ 56, 68 ] ], "normalized": [] }, { "id": "14481", "type": "0", "text": [ "data" ], "offsets": [ [ 61, 65 ] ], "normalized": [] }, { "id": "14482", "type": "0", "text": [ "and" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "14483", "type": "0", "text": [ "the" ], "offsets": [ [ 69, 72 ] ], "normalized": [] }, { "id": "14484", "type": "0", "text": [ "mutagenesis" ], "offsets": [ [ 81, 92 ] ], "normalized": [] }, { "id": "14485", "type": "0", "text": [ "results" ], "offsets": [ [ 89, 96 ] ], "normalized": [] }, { "id": "14486", "type": "0", "text": [ "also" ], "offsets": [ [ 94, 98 ] ], "normalized": [] }, { "id": "14487", "type": "0", "text": [ "suggests" ], "offsets": [ [ 103, 111 ] ], "normalized": [] }, { "id": "14488", "type": "0", "text": [ "that" ], "offsets": [ [ 108, 112 ] ], "normalized": [] }, { "id": "14489", "type": "0", "text": [ "the" ], "offsets": [ [ 112, 115 ] ], "normalized": [] }, { "id": "14490", "type": "0", "text": [ "erythroid" ], "offsets": [ [ 122, 131 ] ], "normalized": [] }, { "id": "14491", "type": "0", "text": [ "lineage-" ], "offsets": [ [ 131, 139 ] ], "normalized": [] }, { "id": "14492", "type": "0", "text": [ "and" ], "offsets": [ [ 135, 138 ] ], "normalized": [] }, { "id": "14493", "type": "0", "text": [ "developmental" ], "offsets": [ [ 149, 162 ] ], "normalized": [] }, { "id": "14494", "type": "0", "text": [ "stage-specific" ], "offsets": [ [ 164, 178 ] ], "normalized": [] }, { "id": "14495", "type": "0", "text": [ "regulation" ], "offsets": [ [ 175, 185 ] ], "normalized": [] }, { "id": "14496", "type": "0", "text": [ "of" ], "offsets": [ [ 178, 180 ] ], "normalized": [] }, { "id": "14497", "type": "1", "text": [ "human" ], "offsets": [ [ 184, 189 ] ], "normalized": [] }, { "id": "14498", "type": "2", "text": [ "alpha-like" ], "offsets": [ [ 195, 205 ] ], "normalized": [] }, { "id": "14499", "type": "2", "text": [ "globin" ], "offsets": [ [ 202, 208 ] ], "normalized": [] }, { "id": "14500", "type": "2", "text": [ "promoters" ], "offsets": [ [ 212, 221 ] ], "normalized": [] }, { "id": "14501", "type": "0", "text": [ "is" ], "offsets": [ [ 215, 217 ] ], "normalized": [] }, { "id": "14502", "type": "0", "text": [ "indeed" ], "offsets": [ [ 222, 228 ] ], "normalized": [] }, { "id": "14503", "type": "0", "text": [ "modulated" ], "offsets": [ [ 232, 241 ] ], "normalized": [] }, { "id": "14504", "type": "0", "text": [ "by" ], "offsets": [ [ 235, 237 ] ], "normalized": [] }, { "id": "14505", "type": "0", "text": [ "stable" ], "offsets": [ [ 242, 248 ] ], "normalized": [] }, { "id": "14506", "type": "0", "text": [ "binding" ], "offsets": [ [ 250, 257 ] ], "normalized": [] }, { "id": "14507", "type": "0", "text": [ "of" ], "offsets": [ [ 253, 255 ] ], "normalized": [] }, { "id": "14508", "type": "9", "text": [ "specific" ], "offsets": [ [ 262, 270 ] ], "normalized": [] }, { "id": "14509", "type": "10", "text": [ "nuclear" ], "offsets": [ [ 270, 277 ] ], "normalized": [] }, { "id": "14510", "type": "10", "text": [ "factors" ], "offsets": [ [ 278, 285 ] ], "normalized": [] }, { "id": "14511", "type": "0", "text": [ "in" ], "offsets": [ [ 281, 283 ] ], "normalized": [] }, { "id": "14512", "type": "0", "text": [ "vivo" ], "offsets": [ [ 286, 290 ] ], "normalized": [] }, { "id": "14513", "type": "0", "text": [ "." ], "offsets": [ [ 288, 289 ] ], "normalized": [] } ]
[]
[]
[]
14514
NULL
[]
[ { "id": "14515", "type": "0", "text": [ "Nitric" ], "offsets": [ [ 7, 13 ] ], "normalized": [] }, { "id": "14516", "type": "0", "text": [ "oxide-stimulated" ], "offsets": [ [ 24, 40 ] ], "normalized": [] }, { "id": "14517", "type": "0", "text": [ "guanine" ], "offsets": [ [ 32, 39 ] ], "normalized": [] }, { "id": "14518", "type": "0", "text": [ "nucleotide" ], "offsets": [ [ 43, 53 ] ], "normalized": [] }, { "id": "14519", "type": "0", "text": [ "exchange" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "14520", "type": "0", "text": [ "on" ], "offsets": [ [ 55, 57 ] ], "normalized": [] }, { "id": "14521", "type": "9", "text": [ "p21ras" ], "offsets": [ [ 62, 68 ] ], "normalized": [] }, { "id": "14522", "type": "0", "text": [ "." ], "offsets": [ [ 64, 65 ] ], "normalized": [] } ]
[]
[]
[]
14523
NULL
[]
[ { "id": "14524", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "14525", "type": "1", "text": [ "protooncogene" ], "offsets": [ [ 18, 31 ] ], "normalized": [] }, { "id": "14526", "type": "2", "text": [ "p21ras" ], "offsets": [ [ 25, 31 ] ], "normalized": [] }, { "id": "14527", "type": "0", "text": [ "," ], "offsets": [ [ 27, 28 ] ], "normalized": [] }, { "id": "14528", "type": "0", "text": [ "a" ], "offsets": [ [ 29, 30 ] ], "normalized": [] }, { "id": "14529", "type": "9", "text": [ "monomeric" ], "offsets": [ [ 39, 48 ] ], "normalized": [] }, { "id": "14530", "type": "10", "text": [ "G" ], "offsets": [ [ 41, 42 ] ], "normalized": [] }, { "id": "14531", "type": "10", "text": [ "protein" ], "offsets": [ [ 49, 56 ] ], "normalized": [] }, { "id": "14532", "type": "10", "text": [ "family" ], "offsets": [ [ 56, 62 ] ], "normalized": [] }, { "id": "14533", "type": "10", "text": [ "member" ], "offsets": [ [ 63, 69 ] ], "normalized": [] }, { "id": "14534", "type": "0", "text": [ "," ], "offsets": [ [ 65, 66 ] ], "normalized": [] }, { "id": "14535", "type": "0", "text": [ "plays" ], "offsets": [ [ 71, 76 ] ], "normalized": [] }, { "id": "14536", "type": "0", "text": [ "a" ], "offsets": [ [ 73, 74 ] ], "normalized": [] }, { "id": "14537", "type": "0", "text": [ "critical" ], "offsets": [ [ 82, 90 ] ], "normalized": [] }, { "id": "14538", "type": "0", "text": [ "role" ], "offsets": [ [ 87, 91 ] ], "normalized": [] }, { "id": "14539", "type": "0", "text": [ "in" ], "offsets": [ [ 90, 92 ] ], "normalized": [] }, { "id": "14540", "type": "0", "text": [ "converting" ], "offsets": [ [ 101, 111 ] ], "normalized": [] }, { "id": "14541", "type": "0", "text": [ "extracellular" ], "offsets": [ [ 115, 128 ] ], "normalized": [] }, { "id": "14542", "type": "0", "text": [ "signals" ], "offsets": [ [ 123, 130 ] ], "normalized": [] }, { "id": "14543", "type": "0", "text": [ "into" ], "offsets": [ [ 128, 132 ] ], "normalized": [] }, { "id": "14544", "type": "0", "text": [ "intracellular" ], "offsets": [ [ 142, 155 ] ], "normalized": [] }, { "id": "14545", "type": "0", "text": [ "biochemical" ], "offsets": [ [ 154, 165 ] ], "normalized": [] }, { "id": "14546", "type": "0", "text": [ "events" ], "offsets": [ [ 161, 167 ] ], "normalized": [] }, { "id": "14547", "type": "0", "text": [ "." ], "offsets": [ [ 163, 164 ] ], "normalized": [] } ]
[]
[]
[]
14548
NULL
[]
[ { "id": "14549", "type": "0", "text": [ "Here" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "14550", "type": "0", "text": [ "," ], "offsets": [ [ 7, 8 ] ], "normalized": [] }, { "id": "14551", "type": "0", "text": [ "we" ], "offsets": [ [ 10, 12 ] ], "normalized": [] }, { "id": "14552", "type": "0", "text": [ "report" ], "offsets": [ [ 17, 23 ] ], "normalized": [] }, { "id": "14553", "type": "0", "text": [ "that" ], "offsets": [ [ 22, 26 ] ], "normalized": [] }, { "id": "14554", "type": "0", "text": [ "nitric" ], "offsets": [ [ 29, 35 ] ], "normalized": [] }, { "id": "14555", "type": "0", "text": [ "oxide" ], "offsets": [ [ 35, 40 ] ], "normalized": [] }, { "id": "14556", "type": "0", "text": [ "(" ], "offsets": [ [ 37, 38 ] ], "normalized": [] }, { "id": "14557", "type": "0", "text": [ "NO" ], "offsets": [ [ 40, 42 ] ], "normalized": [] }, { "id": "14558", "type": "0", "text": [ ")" ], "offsets": [ [ 42, 43 ] ], "normalized": [] }, { "id": "14559", "type": "0", "text": [ "activates" ], "offsets": [ [ 52, 61 ] ], "normalized": [] }, { "id": "14560", "type": "1", "text": [ "p21ras" ], "offsets": [ [ 59, 65 ] ], "normalized": [] }, { "id": "14561", "type": "0", "text": [ "in" ], "offsets": [ [ 62, 64 ] ], "normalized": [] }, { "id": "14562", "type": "7", "text": [ "human" ], "offsets": [ [ 68, 73 ] ], "normalized": [] }, { "id": "14563", "type": "8", "text": [ "T" ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "14564", "type": "8", "text": [ "cells" ], "offsets": [ [ 76, 81 ] ], "normalized": [] }, { "id": "14565", "type": "0", "text": [ "as" ], "offsets": [ [ 79, 81 ] ], "normalized": [] }, { "id": "14566", "type": "0", "text": [ "evidenced" ], "offsets": [ [ 89, 98 ] ], "normalized": [] }, { "id": "14567", "type": "0", "text": [ "by" ], "offsets": [ [ 92, 94 ] ], "normalized": [] }, { "id": "14568", "type": "0", "text": [ "an" ], "offsets": [ [ 95, 97 ] ], "normalized": [] }, { "id": "14569", "type": "0", "text": [ "increase" ], "offsets": [ [ 104, 112 ] ], "normalized": [] }, { "id": "14570", "type": "0", "text": [ "in" ], "offsets": [ [ 107, 109 ] ], "normalized": [] }, { "id": "14571", "type": "9", "text": [ "GTP-bound" ], "offsets": [ [ 117, 126 ] ], "normalized": [] }, { "id": "14572", "type": "10", "text": [ "p21ras" ], "offsets": [ [ 124, 130 ] ], "normalized": [] }, { "id": "14573", "type": "0", "text": [ "." ], "offsets": [ [ 126, 127 ] ], "normalized": [] } ]
[]
[]
[]
14574
NULL
[]
[ { "id": "14575", "type": "0", "text": [ "In" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14576", "type": "0", "text": [ "vitro" ], "offsets": [ [ 9, 14 ] ], "normalized": [] }, { "id": "14577", "type": "0", "text": [ "studies" ], "offsets": [ [ 17, 24 ] ], "normalized": [] }, { "id": "14578", "type": "0", "text": [ "using" ], "offsets": [ [ 23, 28 ] ], "normalized": [] }, { "id": "14579", "type": "9", "text": [ "pure" ], "offsets": [ [ 28, 32 ] ], "normalized": [] }, { "id": "14580", "type": "10", "text": [ "recombinant" ], "offsets": [ [ 40, 51 ] ], "normalized": [] }, { "id": "14581", "type": "10", "text": [ "p21ras" ], "offsets": [ [ 47, 53 ] ], "normalized": [] }, { "id": "14582", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 59, 70 ] ], "normalized": [] }, { "id": "14583", "type": "0", "text": [ "that" ], "offsets": [ [ 64, 68 ] ], "normalized": [] }, { "id": "14584", "type": "0", "text": [ "the" ], "offsets": [ [ 68, 71 ] ], "normalized": [] }, { "id": "14585", "type": "0", "text": [ "activation" ], "offsets": [ [ 79, 89 ] ], "normalized": [] }, { "id": "14586", "type": "0", "text": [ "is" ], "offsets": [ [ 82, 84 ] ], "normalized": [] }, { "id": "14587", "type": "0", "text": [ "direct" ], "offsets": [ [ 89, 95 ] ], "normalized": [] }, { "id": "14588", "type": "0", "text": [ "and" ], "offsets": [ [ 93, 96 ] ], "normalized": [] }, { "id": "14589", "type": "0", "text": [ "reversible" ], "offsets": [ [ 104, 114 ] ], "normalized": [] }, { "id": "14590", "type": "0", "text": [ "." ], "offsets": [ [ 106, 107 ] ], "normalized": [] } ]
[]
[]
[]
14591
NULL
[]
[ { "id": "14592", "type": "0", "text": [ "Circular" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "14593", "type": "0", "text": [ "dichroism" ], "offsets": [ [ 19, 28 ] ], "normalized": [] }, { "id": "14594", "type": "0", "text": [ "analysis" ], "offsets": [ [ 28, 36 ] ], "normalized": [] }, { "id": "14595", "type": "0", "text": [ "reveals" ], "offsets": [ [ 36, 43 ] ], "normalized": [] }, { "id": "14596", "type": "0", "text": [ "that" ], "offsets": [ [ 41, 45 ] ], "normalized": [] }, { "id": "14597", "type": "0", "text": [ "NO" ], "offsets": [ [ 44, 46 ] ], "normalized": [] }, { "id": "14598", "type": "0", "text": [ "induces" ], "offsets": [ [ 52, 59 ] ], "normalized": [] }, { "id": "14599", "type": "0", "text": [ "a" ], "offsets": [ [ 54, 55 ] ], "normalized": [] }, { "id": "14600", "type": "0", "text": [ "profound" ], "offsets": [ [ 63, 71 ] ], "normalized": [] }, { "id": "14601", "type": "0", "text": [ "conformational" ], "offsets": [ [ 78, 92 ] ], "normalized": [] }, { "id": "14602", "type": "0", "text": [ "change" ], "offsets": [ [ 85, 91 ] ], "normalized": [] }, { "id": "14603", "type": "0", "text": [ "in" ], "offsets": [ [ 88, 90 ] ], "normalized": [] }, { "id": "14604", "type": "1", "text": [ "p21ras" ], "offsets": [ [ 95, 101 ] ], "normalized": [] }, { "id": "14605", "type": "0", "text": [ "in" ], "offsets": [ [ 98, 100 ] ], "normalized": [] }, { "id": "14606", "type": "0", "text": [ "association" ], "offsets": [ [ 110, 121 ] ], "normalized": [] }, { "id": "14607", "type": "0", "text": [ "with" ], "offsets": [ [ 115, 119 ] ], "normalized": [] }, { "id": "14608", "type": "0", "text": [ "GDP/GTP" ], "offsets": [ [ 123, 130 ] ], "normalized": [] }, { "id": "14609", "type": "0", "text": [ "exchange" ], "offsets": [ [ 132, 140 ] ], "normalized": [] }, { "id": "14610", "type": "0", "text": [ "." ], "offsets": [ [ 134, 135 ] ], "normalized": [] } ]
[]
[]
[]
14611
NULL
[]
[ { "id": "14612", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "14613", "type": "0", "text": [ "mechanism" ], "offsets": [ [ 14, 23 ] ], "normalized": [] }, { "id": "14614", "type": "0", "text": [ "of" ], "offsets": [ [ 17, 19 ] ], "normalized": [] }, { "id": "14615", "type": "0", "text": [ "activation" ], "offsets": [ [ 28, 38 ] ], "normalized": [] }, { "id": "14616", "type": "0", "text": [ "is" ], "offsets": [ [ 31, 33 ] ], "normalized": [] }, { "id": "14617", "type": "0", "text": [ "due" ], "offsets": [ [ 35, 38 ] ], "normalized": [] }, { "id": "14618", "type": "0", "text": [ "to" ], "offsets": [ [ 38, 40 ] ], "normalized": [] }, { "id": "14619", "type": "0", "text": [ "S-nitrosylation" ], "offsets": [ [ 54, 69 ] ], "normalized": [] }, { "id": "14620", "type": "0", "text": [ "of" ], "offsets": [ [ 57, 59 ] ], "normalized": [] }, { "id": "14621", "type": "0", "text": [ "a" ], "offsets": [ [ 59, 60 ] ], "normalized": [] }, { "id": "14622", "type": "0", "text": [ "critical" ], "offsets": [ [ 68, 76 ] ], "normalized": [] }, { "id": "14623", "type": "0", "text": [ "cysteine" ], "offsets": [ [ 77, 85 ] ], "normalized": [] }, { "id": "14624", "type": "0", "text": [ "residue" ], "offsets": [ [ 85, 92 ] ], "normalized": [] }, { "id": "14625", "type": "0", "text": [ "which" ], "offsets": [ [ 91, 96 ] ], "normalized": [] }, { "id": "14626", "type": "0", "text": [ "stimulates" ], "offsets": [ [ 102, 112 ] ], "normalized": [] }, { "id": "14627", "type": "0", "text": [ "guanine" ], "offsets": [ [ 110, 117 ] ], "normalized": [] }, { "id": "14628", "type": "0", "text": [ "nucleotide" ], "offsets": [ [ 121, 131 ] ], "normalized": [] }, { "id": "14629", "type": "0", "text": [ "exchange" ], "offsets": [ [ 130, 138 ] ], "normalized": [] }, { "id": "14630", "type": "0", "text": [ "." ], "offsets": [ [ 132, 133 ] ], "normalized": [] } ]
[]
[]
[]
14631
NULL
[]
[ { "id": "14632", "type": "0", "text": [ "Furthermore" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "14633", "type": "0", "text": [ "," ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "14634", "type": "0", "text": [ "we" ], "offsets": [ [ 17, 19 ] ], "normalized": [] }, { "id": "14635", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 29, 40 ] ], "normalized": [] }, { "id": "14636", "type": "0", "text": [ "that" ], "offsets": [ [ 34, 38 ] ], "normalized": [] }, { "id": "14637", "type": "9", "text": [ "p21ras" ], "offsets": [ [ 41, 47 ] ], "normalized": [] }, { "id": "14638", "type": "0", "text": [ "is" ], "offsets": [ [ 44, 46 ] ], "normalized": [] }, { "id": "14639", "type": "0", "text": [ "essential" ], "offsets": [ [ 54, 63 ] ], "normalized": [] }, { "id": "14640", "type": "0", "text": [ "for" ], "offsets": [ [ 58, 61 ] ], "normalized": [] }, { "id": "14641", "type": "0", "text": [ "NO-induced" ], "offsets": [ [ 69, 79 ] ], "normalized": [] }, { "id": "14642", "type": "0", "text": [ "downstream" ], "offsets": [ [ 80, 90 ] ], "normalized": [] }, { "id": "14643", "type": "0", "text": [ "signaling" ], "offsets": [ [ 90, 99 ] ], "normalized": [] }, { "id": "14644", "type": "0", "text": [ "," ], "offsets": [ [ 92, 93 ] ], "normalized": [] }, { "id": "14645", "type": "0", "text": [ "such" ], "offsets": [ [ 97, 101 ] ], "normalized": [] }, { "id": "14646", "type": "0", "text": [ "as" ], "offsets": [ [ 100, 102 ] ], "normalized": [] }, { "id": "14647", "type": "9", "text": [ "NF-kappa" ], "offsets": [ [ 109, 117 ] ], "normalized": [] }, { "id": "14648", "type": "10", "text": [ "B" ], "offsets": [ [ 111, 112 ] ], "normalized": [] }, { "id": "14649", "type": "0", "text": [ "activation" ], "offsets": [ [ 122, 132 ] ], "normalized": [] }, { "id": "14650", "type": "0", "text": [ "," ], "offsets": [ [ 124, 125 ] ], "normalized": [] }, { "id": "14651", "type": "0", "text": [ "and" ], "offsets": [ [ 128, 131 ] ], "normalized": [] }, { "id": "14652", "type": "0", "text": [ "that" ], "offsets": [ [ 133, 137 ] ], "normalized": [] }, { "id": "14653", "type": "0", "text": [ "endogenous" ], "offsets": [ [ 144, 154 ] ], "normalized": [] }, { "id": "14654", "type": "0", "text": [ "NO" ], "offsets": [ [ 147, 149 ] ], "normalized": [] }, { "id": "14655", "type": "0", "text": [ "can" ], "offsets": [ [ 151, 154 ] ], "normalized": [] }, { "id": "14656", "type": "0", "text": [ "activate" ], "offsets": [ [ 160, 168 ] ], "normalized": [] }, { "id": "14657", "type": "9", "text": [ "p21ras" ], "offsets": [ [ 167, 173 ] ], "normalized": [] }, { "id": "14658", "type": "0", "text": [ "in" ], "offsets": [ [ 170, 172 ] ], "normalized": [] }, { "id": "14659", "type": "0", "text": [ "the" ], "offsets": [ [ 174, 177 ] ], "normalized": [] }, { "id": "14660", "type": "0", "text": [ "same" ], "offsets": [ [ 179, 183 ] ], "normalized": [] }, { "id": "14661", "type": "0", "text": [ "cell" ], "offsets": [ [ 184, 188 ] ], "normalized": [] }, { "id": "14662", "type": "0", "text": [ "." ], "offsets": [ [ 186, 187 ] ], "normalized": [] } ]
[]
[]
[]
14663
NULL
[]
[ { "id": "14664", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14665", "type": "0", "text": [ "studies" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "14666", "type": "0", "text": [ "identify" ], "offsets": [ [ 23, 31 ] ], "normalized": [] }, { "id": "14667", "type": "1", "text": [ "p21ras" ], "offsets": [ [ 30, 36 ] ], "normalized": [] }, { "id": "14668", "type": "0", "text": [ "as" ], "offsets": [ [ 33, 35 ] ], "normalized": [] }, { "id": "14669", "type": "0", "text": [ "a" ], "offsets": [ [ 35, 36 ] ], "normalized": [] }, { "id": "14670", "type": "0", "text": [ "target" ], "offsets": [ [ 42, 48 ] ], "normalized": [] }, { "id": "14671", "type": "0", "text": [ "of" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "14672", "type": "0", "text": [ "the" ], "offsets": [ [ 49, 52 ] ], "normalized": [] }, { "id": "14673", "type": "0", "text": [ "same" ], "offsets": [ [ 54, 58 ] ], "normalized": [] }, { "id": "14674", "type": "0", "text": [ "cell" ], "offsets": [ [ 59, 63 ] ], "normalized": [] }, { "id": "14675", "type": "0", "text": [ "." ], "offsets": [ [ 61, 62 ] ], "normalized": [] } ]
[]
[]
[]
14676
NULL
[]
[ { "id": "14677", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "14678", "type": "0", "text": [ "studies" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "14679", "type": "0", "text": [ "identify" ], "offsets": [ [ 23, 31 ] ], "normalized": [] }, { "id": "14680", "type": "1", "text": [ "p21ras" ], "offsets": [ [ 30, 36 ] ], "normalized": [] }, { "id": "14681", "type": "0", "text": [ "as" ], "offsets": [ [ 33, 35 ] ], "normalized": [] }, { "id": "14682", "type": "0", "text": [ "a" ], "offsets": [ [ 35, 36 ] ], "normalized": [] }, { "id": "14683", "type": "0", "text": [ "target" ], "offsets": [ [ 42, 48 ] ], "normalized": [] }, { "id": "14684", "type": "0", "text": [ "of" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "14685", "type": "0", "text": [ "NO" ], "offsets": [ [ 48, 50 ] ], "normalized": [] }, { "id": "14686", "type": "0", "text": [ "in" ], "offsets": [ [ 51, 53 ] ], "normalized": [] }, { "id": "14687", "type": "7", "text": [ "T" ], "offsets": [ [ 53, 54 ] ], "normalized": [] }, { "id": "14688", "type": "8", "text": [ "cells" ], "offsets": [ [ 59, 64 ] ], "normalized": [] }, { "id": "14689", "type": "0", "text": [ "and" ], "offsets": [ [ 63, 66 ] ], "normalized": [] }, { "id": "14690", "type": "0", "text": [ "suggest" ], "offsets": [ [ 71, 78 ] ], "normalized": [] }, { "id": "14691", "type": "0", "text": [ "that" ], "offsets": [ [ 76, 80 ] ], "normalized": [] }, { "id": "14692", "type": "0", "text": [ "NO" ], "offsets": [ [ 79, 81 ] ], "normalized": [] }, { "id": "14693", "type": "0", "text": [ "activates" ], "offsets": [ [ 89, 98 ] ], "normalized": [] }, { "id": "14694", "type": "1", "text": [ "p21ras" ], "offsets": [ [ 96, 102 ] ], "normalized": [] }, { "id": "14695", "type": "0", "text": [ "by" ], "offsets": [ [ 99, 101 ] ], "normalized": [] }, { "id": "14696", "type": "0", "text": [ "an" ], "offsets": [ [ 102, 104 ] ], "normalized": [] }, { "id": "14697", "type": "0", "text": [ "action" ], "offsets": [ [ 109, 115 ] ], "normalized": [] }, { "id": "14698", "type": "0", "text": [ "which" ], "offsets": [ [ 115, 120 ] ], "normalized": [] }, { "id": "14699", "type": "0", "text": [ "mimics" ], "offsets": [ [ 122, 128 ] ], "normalized": [] }, { "id": "14700", "type": "0", "text": [ "that" ], "offsets": [ [ 127, 131 ] ], "normalized": [] }, { "id": "14701", "type": "0", "text": [ "of" ], "offsets": [ [ 130, 132 ] ], "normalized": [] }, { "id": "14702", "type": "9", "text": [ "guanine" ], "offsets": [ [ 138, 145 ] ], "normalized": [] }, { "id": "14703", "type": "10", "text": [ "nucleotide" ], "offsets": [ [ 149, 159 ] ], "normalized": [] }, { "id": "14704", "type": "10", "text": [ "exchange" ], "offsets": [ [ 158, 166 ] ], "normalized": [] }, { "id": "14705", "type": "10", "text": [ "factors" ], "offsets": [ [ 166, 173 ] ], "normalized": [] }, { "id": "14706", "type": "0", "text": [ "." ], "offsets": [ [ 168, 169 ] ], "normalized": [] } ]
[]
[]
[]
14707
NULL
[]
[ { "id": "14708", "type": "1", "text": [ "Interleukin-2" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "14709", "type": "2", "text": [ "promoter" ], "offsets": [ [ 23, 31 ] ], "normalized": [] }, { "id": "14710", "type": "0", "text": [ "activity" ], "offsets": [ [ 32, 40 ] ], "normalized": [] }, { "id": "14711", "type": "0", "text": [ "in" ], "offsets": [ [ 35, 37 ] ], "normalized": [] }, { "id": "14712", "type": "5", "text": [ "Epstein-Barr" ], "offsets": [ [ 48, 60 ] ], "normalized": [] }, { "id": "14713", "type": "6", "text": [ "virus-transformed" ], "offsets": [ [ 66, 83 ] ], "normalized": [] }, { "id": "14714", "type": "6", "text": [ "B" ], "offsets": [ [ 68, 69 ] ], "normalized": [] }, { "id": "14715", "type": "6", "text": [ "lymphocytes" ], "offsets": [ [ 80, 91 ] ], "normalized": [] }, { "id": "14716", "type": "0", "text": [ "is" ], "offsets": [ [ 83, 85 ] ], "normalized": [] }, { "id": "14717", "type": "0", "text": [ "controlled" ], "offsets": [ [ 94, 104 ] ], "normalized": [] }, { "id": "14718", "type": "0", "text": [ "by" ], "offsets": [ [ 97, 99 ] ], "normalized": [] }, { "id": "14719", "type": "9", "text": [ "nuclear" ], "offsets": [ [ 105, 112 ] ], "normalized": [] }, { "id": "14720", "type": "10", "text": [ "factor-chi" ], "offsets": [ [ 116, 126 ] ], "normalized": [] }, { "id": "14721", "type": "10", "text": [ "B" ], "offsets": [ [ 118, 119 ] ], "normalized": [] }, { "id": "14722", "type": "0", "text": [ "." ], "offsets": [ [ 120, 121 ] ], "normalized": [] } ]
[]
[]
[]
14723
NULL
[]
[ { "id": "14724", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "14725", "type": "0", "text": [ "regulation" ], "offsets": [ [ 15, 25 ] ], "normalized": [] }, { "id": "14726", "type": "0", "text": [ "of" ], "offsets": [ [ 18, 20 ] ], "normalized": [] }, { "id": "14727", "type": "1", "text": [ "interleukin" ], "offsets": [ [ 30, 41 ] ], "normalized": [] }, { "id": "14728", "type": "2", "text": [ "(" ], "offsets": [ [ 32, 33 ] ], "normalized": [] }, { "id": "14729", "type": "2", "text": [ "IL" ], "offsets": [ [ 35, 37 ] ], "normalized": [] }, { "id": "14730", "type": "2", "text": [ ")" ], "offsets": [ [ 37, 38 ] ], "normalized": [] }, { "id": "14731", "type": "2", "text": [ "-2" ], "offsets": [ [ 40, 42 ] ], "normalized": [] }, { "id": "14732", "type": "2", "text": [ "gene" ], "offsets": [ [ 45, 49 ] ], "normalized": [] }, { "id": "14733", "type": "0", "text": [ "expression" ], "offsets": [ [ 56, 66 ] ], "normalized": [] }, { "id": "14734", "type": "0", "text": [ "has" ], "offsets": [ [ 60, 63 ] ], "normalized": [] }, { "id": "14735", "type": "0", "text": [ "been" ], "offsets": [ [ 65, 69 ] ], "normalized": [] }, { "id": "14736", "type": "0", "text": [ "investigated" ], "offsets": [ [ 78, 90 ] ], "normalized": [] }, { "id": "14737", "type": "0", "text": [ "mainly" ], "offsets": [ [ 85, 91 ] ], "normalized": [] }, { "id": "14738", "type": "0", "text": [ "in" ], "offsets": [ [ 88, 90 ] ], "normalized": [] }, { "id": "14739", "type": "7", "text": [ "T" ], "offsets": [ [ 90, 91 ] ], "normalized": [] }, { "id": "14740", "type": "8", "text": [ "lymphocytes" ], "offsets": [ [ 102, 113 ] ], "normalized": [] }, { "id": "14741", "type": "0", "text": [ "," ], "offsets": [ [ 104, 105 ] ], "normalized": [] }, { "id": "14742", "type": "0", "text": [ "the" ], "offsets": [ [ 108, 111 ] ], "normalized": [] }, { "id": "14743", "type": "0", "text": [ "predominant" ], "offsets": [ [ 120, 131 ] ], "normalized": [] }, { "id": "14744", "type": "0", "text": [ "producers" ], "offsets": [ [ 130, 139 ] ], "normalized": [] }, { "id": "14745", "type": "0", "text": [ "of" ], "offsets": [ [ 133, 135 ] ], "normalized": [] }, { "id": "14746", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 138, 142 ] ], "normalized": [] }, { "id": "14747", "type": "0", "text": [ "." ], "offsets": [ [ 140, 141 ] ], "normalized": [] } ]
[]
[]
[]
14748
NULL
[]
[ { "id": "14749", "type": "0", "text": [ "However" ], "offsets": [ [ 8, 15 ] ], "normalized": [] }, { "id": "14750", "type": "0", "text": [ "," ], "offsets": [ [ 10, 11 ] ], "normalized": [] }, { "id": "14751", "type": "7", "text": [ "B" ], "offsets": [ [ 12, 13 ] ], "normalized": [] }, { "id": "14752", "type": "8", "text": [ "cells" ], "offsets": [ [ 18, 23 ] ], "normalized": [] }, { "id": "14753", "type": "0", "text": [ "can" ], "offsets": [ [ 22, 25 ] ], "normalized": [] }, { "id": "14754", "type": "0", "text": [ "also" ], "offsets": [ [ 27, 31 ] ], "normalized": [] }, { "id": "14755", "type": "0", "text": [ "synthesize" ], "offsets": [ [ 38, 48 ] ], "normalized": [] }, { "id": "14756", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 43, 47 ] ], "normalized": [] }, { "id": "14757", "type": "0", "text": [ "." ], "offsets": [ [ 45, 46 ] ], "normalized": [] } ]
[]
[]
[]
14758
NULL
[]
[ { "id": "14759", "type": "0", "text": [ "In" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14760", "type": "0", "text": [ "the" ], "offsets": [ [ 7, 10 ] ], "normalized": [] }, { "id": "14761", "type": "0", "text": [ "present" ], "offsets": [ [ 15, 22 ] ], "normalized": [] }, { "id": "14762", "type": "0", "text": [ "study" ], "offsets": [ [ 21, 26 ] ], "normalized": [] }, { "id": "14763", "type": "0", "text": [ "we" ], "offsets": [ [ 24, 26 ] ], "normalized": [] }, { "id": "14764", "type": "0", "text": [ "analyzed" ], "offsets": [ [ 33, 41 ] ], "normalized": [] }, { "id": "14765", "type": "0", "text": [ "the" ], "offsets": [ [ 37, 40 ] ], "normalized": [] }, { "id": "14766", "type": "0", "text": [ "control" ], "offsets": [ [ 45, 52 ] ], "normalized": [] }, { "id": "14767", "type": "0", "text": [ "of" ], "offsets": [ [ 48, 50 ] ], "normalized": [] }, { "id": "14768", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 53, 57 ] ], "normalized": [] }, { "id": "14769", "type": "2", "text": [ "promoter" ], "offsets": [ [ 62, 70 ] ], "normalized": [] }, { "id": "14770", "type": "0", "text": [ "activity" ], "offsets": [ [ 71, 79 ] ], "normalized": [] }, { "id": "14771", "type": "0", "text": [ "in" ], "offsets": [ [ 74, 76 ] ], "normalized": [] }, { "id": "14772", "type": "5", "text": [ "Epstein-Barr" ], "offsets": [ [ 87, 99 ] ], "normalized": [] }, { "id": "14773", "type": "6", "text": [ "virus" ], "offsets": [ [ 93, 98 ] ], "normalized": [] }, { "id": "14774", "type": "6", "text": [ "(" ], "offsets": [ [ 95, 96 ] ], "normalized": [] }, { "id": "14775", "type": "6", "text": [ "EBV" ], "offsets": [ [ 99, 102 ] ], "normalized": [] }, { "id": "14776", "type": "6", "text": [ ")" ], "offsets": [ [ 101, 102 ] ], "normalized": [] }, { "id": "14777", "type": "6", "text": [ "-transformed" ], "offsets": [ [ 114, 126 ] ], "normalized": [] }, { "id": "14778", "type": "6", "text": [ "B" ], "offsets": [ [ 116, 117 ] ], "normalized": [] }, { "id": "14779", "type": "6", "text": [ "cell" ], "offsets": [ [ 121, 125 ] ], "normalized": [] }, { "id": "14780", "type": "6", "text": [ "clones" ], "offsets": [ [ 128, 134 ] ], "normalized": [] }, { "id": "14781", "type": "0", "text": [ "which" ], "offsets": [ [ 134, 139 ] ], "normalized": [] }, { "id": "14782", "type": "0", "text": [ "are" ], "offsets": [ [ 138, 141 ] ], "normalized": [] }, { "id": "14783", "type": "0", "text": [ "capable" ], "offsets": [ [ 146, 153 ] ], "normalized": [] }, { "id": "14784", "type": "0", "text": [ "of" ], "offsets": [ [ 149, 151 ] ], "normalized": [] }, { "id": "14785", "type": "0", "text": [ "secreting" ], "offsets": [ [ 159, 168 ] ], "normalized": [] }, { "id": "14786", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 164, 168 ] ], "normalized": [] }, { "id": "14787", "type": "0", "text": [ "at" ], "offsets": [ [ 167, 169 ] ], "normalized": [] }, { "id": "14788", "type": "0", "text": [ "a" ], "offsets": [ [ 169, 170 ] ], "normalized": [] }, { "id": "14789", "type": "0", "text": [ "low" ], "offsets": [ [ 173, 176 ] ], "normalized": [] }, { "id": "14790", "type": "0", "text": [ "level" ], "offsets": [ [ 179, 184 ] ], "normalized": [] }, { "id": "14791", "type": "0", "text": [ "after" ], "offsets": [ [ 185, 190 ] ], "normalized": [] }, { "id": "14792", "type": "0", "text": [ "stimulation" ], "offsets": [ [ 197, 208 ] ], "normalized": [] }, { "id": "14793", "type": "0", "text": [ "with" ], "offsets": [ [ 202, 206 ] ], "normalized": [] }, { "id": "14794", "type": "0", "text": [ "phorbol" ], "offsets": [ [ 210, 217 ] ], "normalized": [] }, { "id": "14795", "type": "0", "text": [ "12-myristate" ], "offsets": [ [ 223, 235 ] ], "normalized": [] }, { "id": "14796", "type": "0", "text": [ "13-acetate" ], "offsets": [ [ 234, 244 ] ], "normalized": [] }, { "id": "14797", "type": "0", "text": [ "and" ], "offsets": [ [ 238, 241 ] ], "normalized": [] }, { "id": "14798", "type": "0", "text": [ "the" ], "offsets": [ [ 242, 245 ] ], "normalized": [] }, { "id": "14799", "type": "0", "text": [ "Ca2+" ], "offsets": [ [ 247, 251 ] ], "normalized": [] }, { "id": "14800", "type": "0", "text": [ "ionophore" ], "offsets": [ [ 257, 266 ] ], "normalized": [] }, { "id": "14801", "type": "0", "text": [ "ionomycin" ], "offsets": [ [ 267, 276 ] ], "normalized": [] }, { "id": "14802", "type": "0", "text": [ "." ], "offsets": [ [ 269, 270 ] ], "normalized": [] } ]
[]
[]
[]
14803
NULL
[]
[ { "id": "14804", "type": "0", "text": [ "Transient" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "14805", "type": "0", "text": [ "transfections" ], "offsets": [ [ 24, 37 ] ], "normalized": [] }, { "id": "14806", "type": "0", "text": [ "using" ], "offsets": [ [ 30, 35 ] ], "normalized": [] }, { "id": "14807", "type": "1", "text": [ "reporter" ], "offsets": [ [ 39, 47 ] ], "normalized": [] }, { "id": "14808", "type": "2", "text": [ "constructs" ], "offsets": [ [ 50, 60 ] ], "normalized": [] }, { "id": "14809", "type": "0", "text": [ "with" ], "offsets": [ [ 55, 59 ] ], "normalized": [] }, { "id": "14810", "type": "0", "text": [ "multiples" ], "offsets": [ [ 65, 74 ] ], "normalized": [] }, { "id": "14811", "type": "0", "text": [ "of" ], "offsets": [ [ 68, 70 ] ], "normalized": [] }, { "id": "14812", "type": "1", "text": [ "transcription" ], "offsets": [ [ 82, 95 ] ], "normalized": [] }, { "id": "14813", "type": "2", "text": [ "factor" ], "offsets": [ [ 89, 95 ] ], "normalized": [] }, { "id": "14814", "type": "2", "text": [ "binding" ], "offsets": [ [ 97, 104 ] ], "normalized": [] }, { "id": "14815", "type": "2", "text": [ "sites" ], "offsets": [ [ 103, 108 ] ], "normalized": [] }, { "id": "14816", "type": "0", "text": [ "from" ], "offsets": [ [ 108, 112 ] ], "normalized": [] }, { "id": "14817", "type": "0", "text": [ "the" ], "offsets": [ [ 112, 115 ] ], "normalized": [] }, { "id": "14818", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 117, 121 ] ], "normalized": [] }, { "id": "14819", "type": "2", "text": [ "promoter" ], "offsets": [ [ 126, 134 ] ], "normalized": [] }, { "id": "14820", "type": "0", "text": [ "[" ], "offsets": [ [ 128, 129 ] ], "normalized": [] }, { "id": "14821", "type": "9", "text": [ "distal" ], "offsets": [ [ 135, 141 ] ], "normalized": [] }, { "id": "14822", "type": "10", "text": [ "nuclear" ], "offsets": [ [ 143, 150 ] ], "normalized": [] }, { "id": "14823", "type": "10", "text": [ "factor" ], "offsets": [ [ 150, 156 ] ], "normalized": [] }, { "id": "14824", "type": "10", "text": [ "(" ], "offsets": [ [ 152, 153 ] ], "normalized": [] }, { "id": "14825", "type": "10", "text": [ "NF" ], "offsets": [ [ 155, 157 ] ], "normalized": [] }, { "id": "14826", "type": "10", "text": [ ")" ], "offsets": [ [ 157, 158 ] ], "normalized": [] }, { "id": "14827", "type": "10", "text": [ "-AT" ], "offsets": [ [ 161, 164 ] ], "normalized": [] }, { "id": "14828", "type": "0", "text": [ "," ], "offsets": [ [ 163, 164 ] ], "normalized": [] }, { "id": "14829", "type": "9", "text": [ "proximal" ], "offsets": [ [ 172, 180 ] ], "normalized": [] }, { "id": "14830", "type": "10", "text": [ "NF-AT" ], "offsets": [ [ 178, 183 ] ], "normalized": [] }, { "id": "14831", "type": "0", "text": [ "," ], "offsets": [ [ 180, 181 ] ], "normalized": [] }, { "id": "14832", "type": "9", "text": [ "AP-1/Octamer" ], "offsets": [ [ 193, 205 ] ], "normalized": [] }, { "id": "14833", "type": "0", "text": [ "(" ], "offsets": [ [ 195, 196 ] ], "normalized": [] }, { "id": "14834", "type": "9", "text": [ "UPS" ], "offsets": [ [ 199, 202 ] ], "normalized": [] }, { "id": "14835", "type": "0", "text": [ ")" ], "offsets": [ [ 201, 202 ] ], "normalized": [] }, { "id": "14836", "type": "0", "text": [ "or" ], "offsets": [ [ 204, 206 ] ], "normalized": [] }, { "id": "14837", "type": "9", "text": [ "NF-chi" ], "offsets": [ [ 211, 217 ] ], "normalized": [] }, { "id": "14838", "type": "10", "text": [ "B" ], "offsets": [ [ 213, 214 ] ], "normalized": [] }, { "id": "14839", "type": "0", "text": [ "(" ], "offsets": [ [ 215, 216 ] ], "normalized": [] }, { "id": "14840", "type": "9", "text": [ "TCEd" ], "offsets": [ [ 220, 224 ] ], "normalized": [] }, { "id": "14841", "type": "0", "text": [ ")" ], "offsets": [ [ 222, 223 ] ], "normalized": [] }, { "id": "14842", "type": "0", "text": [ "sites" ], "offsets": [ [ 228, 233 ] ], "normalized": [] }, { "id": "14843", "type": "0", "text": [ "]" ], "offsets": [ [ 230, 231 ] ], "normalized": [] }, { "id": "14844", "type": "0", "text": [ "were" ], "offsets": [ [ 235, 239 ] ], "normalized": [] }, { "id": "14845", "type": "0", "text": [ "performed" ], "offsets": [ [ 245, 254 ] ], "normalized": [] }, { "id": "14846", "type": "0", "text": [ "." ], "offsets": [ [ 247, 248 ] ], "normalized": [] } ]
[]
[]
[]
14847
NULL
[]
[ { "id": "14848", "type": "0", "text": [ "In" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14849", "type": "5", "text": [ "EBV-transformed" ], "offsets": [ [ 19, 34 ] ], "normalized": [] }, { "id": "14850", "type": "6", "text": [ "B" ], "offsets": [ [ 21, 22 ] ], "normalized": [] }, { "id": "14851", "type": "6", "text": [ "clones" ], "offsets": [ [ 28, 34 ] ], "normalized": [] }, { "id": "14852", "type": "0", "text": [ "," ], "offsets": [ [ 30, 31 ] ], "normalized": [] }, { "id": "14853", "type": "0", "text": [ "the" ], "offsets": [ [ 34, 37 ] ], "normalized": [] }, { "id": "14854", "type": "1", "text": [ "chi" ], "offsets": [ [ 38, 41 ] ], "normalized": [] }, { "id": "14855", "type": "2", "text": [ "B" ], "offsets": [ [ 40, 41 ] ], "normalized": [] }, { "id": "14856", "type": "2", "text": [ "site" ], "offsets": [ [ 45, 49 ] ], "normalized": [] }, { "id": "14857", "type": "0", "text": [ "exerted" ], "offsets": [ [ 53, 60 ] ], "normalized": [] }, { "id": "14858", "type": "0", "text": [ "the" ], "offsets": [ [ 57, 60 ] ], "normalized": [] }, { "id": "14859", "type": "0", "text": [ "strongest" ], "offsets": [ [ 67, 76 ] ], "normalized": [] }, { "id": "14860", "type": "0", "text": [ "inducible" ], "offsets": [ [ 77, 86 ] ], "normalized": [] }, { "id": "14861", "type": "0", "text": [ "activity" ], "offsets": [ [ 86, 94 ] ], "normalized": [] }, { "id": "14862", "type": "0", "text": [ ";" ], "offsets": [ [ 88, 89 ] ], "normalized": [] }, { "id": "14863", "type": "0", "text": [ "the" ], "offsets": [ [ 92, 95 ] ], "normalized": [] }, { "id": "14864", "type": "1", "text": [ "NF-AT" ], "offsets": [ [ 98, 103 ] ], "normalized": [] }, { "id": "14865", "type": "2", "text": [ "binding" ], "offsets": [ [ 106, 113 ] ], "normalized": [] }, { "id": "14866", "type": "2", "text": [ "sites" ], "offsets": [ [ 112, 117 ] ], "normalized": [] }, { "id": "14867", "type": "0", "text": [ "showed" ], "offsets": [ [ 119, 125 ] ], "normalized": [] }, { "id": "14868", "type": "0", "text": [ "either" ], "offsets": [ [ 126, 132 ] ], "normalized": [] }, { "id": "14869", "type": "0", "text": [ "no" ], "offsets": [ [ 129, 131 ] ], "normalized": [] }, { "id": "14870", "type": "0", "text": [ "or" ], "offsets": [ [ 132, 134 ] ], "normalized": [] }, { "id": "14871", "type": "0", "text": [ "only" ], "offsets": [ [ 137, 141 ] ], "normalized": [] }, { "id": "14872", "type": "0", "text": [ "weak" ], "offsets": [ [ 142, 146 ] ], "normalized": [] }, { "id": "14873", "type": "0", "text": [ "activity" ], "offsets": [ [ 151, 159 ] ], "normalized": [] }, { "id": "14874", "type": "0", "text": [ "compared" ], "offsets": [ [ 160, 168 ] ], "normalized": [] }, { "id": "14875", "type": "0", "text": [ "to" ], "offsets": [ [ 163, 165 ] ], "normalized": [] }, { "id": "14876", "type": "5", "text": [ "Jurkat" ], "offsets": [ [ 170, 176 ] ], "normalized": [] }, { "id": "14877", "type": "6", "text": [ "T" ], "offsets": [ [ 172, 173 ] ], "normalized": [] }, { "id": "14878", "type": "6", "text": [ "cells" ], "offsets": [ [ 178, 183 ] ], "normalized": [] }, { "id": "14879", "type": "0", "text": [ "." ], "offsets": [ [ 180, 181 ] ], "normalized": [] } ]
[]
[]
[]
14880
NULL
[]
[ { "id": "14881", "type": "0", "text": [ "An" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14882", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 8, 12 ] ], "normalized": [] }, { "id": "14883", "type": "2", "text": [ "promoter" ], "offsets": [ [ 17, 25 ] ], "normalized": [] }, { "id": "14884", "type": "0", "text": [ "bearing" ], "offsets": [ [ 25, 32 ] ], "normalized": [] }, { "id": "14885", "type": "0", "text": [ "a" ], "offsets": [ [ 27, 28 ] ], "normalized": [] }, { "id": "14886", "type": "0", "text": [ "defective" ], "offsets": [ [ 37, 46 ] ], "normalized": [] }, { "id": "14887", "type": "1", "text": [ "NF-chi" ], "offsets": [ [ 44, 50 ] ], "normalized": [] }, { "id": "14888", "type": "2", "text": [ "B" ], "offsets": [ [ 46, 47 ] ], "normalized": [] }, { "id": "14889", "type": "2", "text": [ "site" ], "offsets": [ [ 51, 55 ] ], "normalized": [] }, { "id": "14890", "type": "0", "text": [ "was" ], "offsets": [ [ 55, 58 ] ], "normalized": [] }, { "id": "14891", "type": "0", "text": [ "completely" ], "offsets": [ [ 66, 76 ] ], "normalized": [] }, { "id": "14892", "type": "0", "text": [ "inactive" ], "offsets": [ [ 75, 83 ] ], "normalized": [] }, { "id": "14893", "type": "0", "text": [ "in" ], "offsets": [ [ 78, 80 ] ], "normalized": [] }, { "id": "14894", "type": "5", "text": [ "EBV-transformed" ], "offsets": [ [ 94, 109 ] ], "normalized": [] }, { "id": "14895", "type": "6", "text": [ "B" ], "offsets": [ [ 96, 97 ] ], "normalized": [] }, { "id": "14896", "type": "6", "text": [ "cells" ], "offsets": [ [ 102, 107 ] ], "normalized": [] }, { "id": "14897", "type": "0", "text": [ "," ], "offsets": [ [ 104, 105 ] ], "normalized": [] }, { "id": "14898", "type": "0", "text": [ "while" ], "offsets": [ [ 110, 115 ] ], "normalized": [] }, { "id": "14899", "type": "0", "text": [ "it" ], "offsets": [ [ 113, 115 ] ], "normalized": [] }, { "id": "14900", "type": "0", "text": [ "still" ], "offsets": [ [ 119, 124 ] ], "normalized": [] }, { "id": "14901", "type": "0", "text": [ "had" ], "offsets": [ [ 123, 126 ] ], "normalized": [] }, { "id": "14902", "type": "0", "text": [ "activity" ], "offsets": [ [ 132, 140 ] ], "normalized": [] }, { "id": "14903", "type": "0", "text": [ "in" ], "offsets": [ [ 135, 137 ] ], "normalized": [] }, { "id": "14904", "type": "5", "text": [ "Jurkat" ], "offsets": [ [ 142, 148 ] ], "normalized": [] }, { "id": "14905", "type": "6", "text": [ "T" ], "offsets": [ [ 144, 145 ] ], "normalized": [] }, { "id": "14906", "type": "6", "text": [ "cells" ], "offsets": [ [ 150, 155 ] ], "normalized": [] }, { "id": "14907", "type": "0", "text": [ "." ], "offsets": [ [ 152, 153 ] ], "normalized": [] } ]
[]
[]
[]
14908
NULL
[]
[ { "id": "14909", "type": "0", "text": [ "In" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "14910", "type": "0", "text": [ "seven" ], "offsets": [ [ 9, 14 ] ], "normalized": [] }, { "id": "14911", "type": "5", "text": [ "EBV-B" ], "offsets": [ [ 15, 20 ] ], "normalized": [] }, { "id": "14912", "type": "6", "text": [ "cell" ], "offsets": [ [ 20, 24 ] ], "normalized": [] }, { "id": "14913", "type": "6", "text": [ "clones" ], "offsets": [ [ 27, 33 ] ], "normalized": [] }, { "id": "14914", "type": "0", "text": [ "or" ], "offsets": [ [ 30, 32 ] ], "normalized": [] }, { "id": "14915", "type": "0", "text": [ "lines" ], "offsets": [ [ 36, 41 ] ], "normalized": [] }, { "id": "14916", "type": "0", "text": [ "differing" ], "offsets": [ [ 46, 55 ] ], "normalized": [] }, { "id": "14917", "type": "0", "text": [ "in" ], "offsets": [ [ 49, 51 ] ], "normalized": [] }, { "id": "14918", "type": "0", "text": [ "their" ], "offsets": [ [ 55, 60 ] ], "normalized": [] }, { "id": "14919", "type": "0", "text": [ "capacity" ], "offsets": [ [ 64, 72 ] ], "normalized": [] }, { "id": "14920", "type": "0", "text": [ "to" ], "offsets": [ [ 67, 69 ] ], "normalized": [] }, { "id": "14921", "type": "0", "text": [ "secrete" ], "offsets": [ [ 75, 82 ] ], "normalized": [] }, { "id": "14922", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 80, 84 ] ], "normalized": [] }, { "id": "14923", "type": "0", "text": [ "," ], "offsets": [ [ 82, 83 ] ], "normalized": [] }, { "id": "14924", "type": "0", "text": [ "the" ], "offsets": [ [ 86, 89 ] ], "normalized": [] }, { "id": "14925", "type": "0", "text": [ "activity" ], "offsets": [ [ 95, 103 ] ], "normalized": [] }, { "id": "14926", "type": "0", "text": [ "of" ], "offsets": [ [ 98, 100 ] ], "normalized": [] }, { "id": "14927", "type": "0", "text": [ "the" ], "offsets": [ [ 102, 105 ] ], "normalized": [] }, { "id": "14928", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 107, 111 ] ], "normalized": [] }, { "id": "14929", "type": "2", "text": [ "promoter" ], "offsets": [ [ 116, 124 ] ], "normalized": [] }, { "id": "14930", "type": "0", "text": [ "correlated" ], "offsets": [ [ 127, 137 ] ], "normalized": [] }, { "id": "14931", "type": "0", "text": [ "well" ], "offsets": [ [ 132, 136 ] ], "normalized": [] }, { "id": "14932", "type": "0", "text": [ "with" ], "offsets": [ [ 137, 141 ] ], "normalized": [] }, { "id": "14933", "type": "0", "text": [ "the" ], "offsets": [ [ 141, 144 ] ], "normalized": [] }, { "id": "14934", "type": "0", "text": [ "status" ], "offsets": [ [ 148, 154 ] ], "normalized": [] }, { "id": "14935", "type": "0", "text": [ "of" ], "offsets": [ [ 151, 153 ] ], "normalized": [] }, { "id": "14936", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 156, 160 ] ], "normalized": [] }, { "id": "14937", "type": "0", "text": [ "secretion" ], "offsets": [ [ 166, 175 ] ], "normalized": [] }, { "id": "14938", "type": "0", "text": [ "." ], "offsets": [ [ 168, 169 ] ], "normalized": [] } ]
[]
[]
[]
14939
NULL
[]
[ { "id": "14940", "type": "0", "text": [ "Similarly" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "14941", "type": "0", "text": [ "," ], "offsets": [ [ 12, 13 ] ], "normalized": [] }, { "id": "14942", "type": "0", "text": [ "a" ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "14943", "type": "1", "text": [ "human" ], "offsets": [ [ 20, 25 ] ], "normalized": [] }, { "id": "14944", "type": "2", "text": [ "immunodeficiency" ], "offsets": [ [ 37, 53 ] ], "normalized": [] }, { "id": "14945", "type": "2", "text": [ "virus" ], "offsets": [ [ 43, 48 ] ], "normalized": [] }, { "id": "14946", "type": "2", "text": [ "promoter" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "14947", "type": "0", "text": [ "," ], "offsets": [ [ 54, 55 ] ], "normalized": [] }, { "id": "14948", "type": "0", "text": [ "whose" ], "offsets": [ [ 60, 65 ] ], "normalized": [] }, { "id": "14949", "type": "0", "text": [ "activity" ], "offsets": [ [ 69, 77 ] ], "normalized": [] }, { "id": "14950", "type": "0", "text": [ "is" ], "offsets": [ [ 72, 74 ] ], "normalized": [] }, { "id": "14951", "type": "0", "text": [ "controlled" ], "offsets": [ [ 83, 93 ] ], "normalized": [] }, { "id": "14952", "type": "0", "text": [ "through" ], "offsets": [ [ 91, 98 ] ], "normalized": [] }, { "id": "14953", "type": "9", "text": [ "chi" ], "offsets": [ [ 95, 98 ] ], "normalized": [] }, { "id": "14954", "type": "10", "text": [ "B" ], "offsets": [ [ 97, 98 ] ], "normalized": [] }, { "id": "14955", "type": "10", "text": [ "factors" ], "offsets": [ [ 105, 112 ] ], "normalized": [] }, { "id": "14956", "type": "0", "text": [ "," ], "offsets": [ [ 107, 108 ] ], "normalized": [] }, { "id": "14957", "type": "0", "text": [ "was" ], "offsets": [ [ 111, 114 ] ], "normalized": [] }, { "id": "14958", "type": "0", "text": [ "found" ], "offsets": [ [ 117, 122 ] ], "normalized": [] }, { "id": "14959", "type": "0", "text": [ "to" ], "offsets": [ [ 120, 122 ] ], "normalized": [] }, { "id": "14960", "type": "0", "text": [ "be" ], "offsets": [ [ 123, 125 ] ], "normalized": [] }, { "id": "14961", "type": "0", "text": [ "active" ], "offsets": [ [ 130, 136 ] ], "normalized": [] }, { "id": "14962", "type": "0", "text": [ "in" ], "offsets": [ [ 133, 135 ] ], "normalized": [] }, { "id": "14963", "type": "0", "text": [ "the" ], "offsets": [ [ 137, 140 ] ], "normalized": [] }, { "id": "14964", "type": "5", "text": [ "IL-2" ], "offsets": [ [ 142, 146 ] ], "normalized": [] }, { "id": "14965", "type": "6", "text": [ "producing" ], "offsets": [ [ 152, 161 ] ], "normalized": [] }, { "id": "14966", "type": "6", "text": [ "EBV-B" ], "offsets": [ [ 158, 163 ] ], "normalized": [] }, { "id": "14967", "type": "6", "text": [ "cells" ], "offsets": [ [ 164, 169 ] ], "normalized": [] }, { "id": "14968", "type": "0", "text": [ "," ], "offsets": [ [ 166, 167 ] ], "normalized": [] }, { "id": "14969", "type": "0", "text": [ "but" ], "offsets": [ [ 170, 173 ] ], "normalized": [] }, { "id": "14970", "type": "0", "text": [ "inactive" ], "offsets": [ [ 179, 187 ] ], "normalized": [] }, { "id": "14971", "type": "0", "text": [ "in" ], "offsets": [ [ 182, 184 ] ], "normalized": [] }, { "id": "14972", "type": "0", "text": [ "the" ], "offsets": [ [ 186, 189 ] ], "normalized": [] }, { "id": "14973", "type": "5", "text": [ "non-IL-2-producing" ], "offsets": [ [ 205, 223 ] ], "normalized": [] }, { "id": "14974", "type": "6", "text": [ "cells" ], "offsets": [ [ 211, 216 ] ], "normalized": [] }, { "id": "14975", "type": "0", "text": [ "." ], "offsets": [ [ 213, 214 ] ], "normalized": [] } ]
[]
[]
[]
14976
NULL
[]
[ { "id": "14977", "type": "0", "text": [ "Electrophoretic" ], "offsets": [ [ 16, 31 ] ], "normalized": [] }, { "id": "14978", "type": "0", "text": [ "mobility" ], "offsets": [ [ 25, 33 ] ], "normalized": [] }, { "id": "14979", "type": "0", "text": [ "shift" ], "offsets": [ [ 31, 36 ] ], "normalized": [] }, { "id": "14980", "type": "0", "text": [ "assays" ], "offsets": [ [ 38, 44 ] ], "normalized": [] }, { "id": "14981", "type": "0", "text": [ "using" ], "offsets": [ [ 44, 49 ] ], "normalized": [] }, { "id": "14982", "type": "0", "text": [ "protein" ], "offsets": [ [ 52, 59 ] ], "normalized": [] }, { "id": "14983", "type": "0", "text": [ "extracts" ], "offsets": [ [ 61, 69 ] ], "normalized": [] }, { "id": "14984", "type": "0", "text": [ "from" ], "offsets": [ [ 66, 70 ] ], "normalized": [] }, { "id": "14985", "type": "5", "text": [ "EBV-B" ], "offsets": [ [ 72, 77 ] ], "normalized": [] }, { "id": "14986", "type": "6", "text": [ "cells" ], "offsets": [ [ 78, 83 ] ], "normalized": [] }, { "id": "14987", "type": "0", "text": [ "and" ], "offsets": [ [ 82, 85 ] ], "normalized": [] }, { "id": "14988", "type": "0", "text": [ "the" ], "offsets": [ [ 86, 89 ] ], "normalized": [] }, { "id": "14989", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 91, 95 ] ], "normalized": [] }, { "id": "14990", "type": "9", "text": [ "NF-chi" ], "offsets": [ [ 98, 104 ] ], "normalized": [] }, { "id": "14991", "type": "10", "text": [ "B" ], "offsets": [ [ 100, 101 ] ], "normalized": [] }, { "id": "14992", "type": "0", "text": [ "probe" ], "offsets": [ [ 106, 111 ] ], "normalized": [] }, { "id": "14993", "type": "0", "text": [ "revealed" ], "offsets": [ [ 115, 123 ] ], "normalized": [] }, { "id": "14994", "type": "0", "text": [ "the" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "14995", "type": "0", "text": [ "constitutive" ], "offsets": [ [ 132, 144 ] ], "normalized": [] }, { "id": "14996", "type": "0", "text": [ "generation" ], "offsets": [ [ 143, 153 ] ], "normalized": [] }, { "id": "14997", "type": "0", "text": [ "of" ], "offsets": [ [ 146, 148 ] ], "normalized": [] }, { "id": "14998", "type": "9", "text": [ "chi" ], "offsets": [ [ 150, 153 ] ], "normalized": [] }, { "id": "14999", "type": "10", "text": [ "B" ], "offsets": [ [ 152, 153 ] ], "normalized": [] }, { "id": "15000", "type": "10", "text": [ "complexes" ], "offsets": [ [ 162, 171 ] ], "normalized": [] }, { "id": "15001", "type": "0", "text": [ "in" ], "offsets": [ [ 165, 167 ] ], "normalized": [] }, { "id": "15002", "type": "5", "text": [ "IL-2-secreting" ], "offsets": [ [ 180, 194 ] ], "normalized": [] }, { "id": "15003", "type": "6", "text": [ "cells" ], "offsets": [ [ 186, 191 ] ], "normalized": [] }, { "id": "15004", "type": "0", "text": [ "consisting" ], "offsets": [ [ 197, 207 ] ], "normalized": [] }, { "id": "15005", "type": "0", "text": [ "mainly" ], "offsets": [ [ 204, 210 ] ], "normalized": [] }, { "id": "15006", "type": "0", "text": [ "of" ], "offsets": [ [ 207, 209 ] ], "normalized": [] }, { "id": "15007", "type": "9", "text": [ "heterodimeric" ], "offsets": [ [ 221, 234 ] ], "normalized": [] }, { "id": "15008", "type": "10", "text": [ "p50/p65" ], "offsets": [ [ 229, 236 ] ], "normalized": [] }, { "id": "15009", "type": "10", "text": [ "complexes" ], "offsets": [ [ 239, 248 ] ], "normalized": [] }, { "id": "15010", "type": "0", "text": [ "." ], "offsets": [ [ 241, 242 ] ], "normalized": [] } ]
[]
[]
[]
15011
NULL
[]
[ { "id": "15012", "type": "0", "text": [ "A" ], "offsets": [ [ 2, 3 ] ], "normalized": [] }, { "id": "15013", "type": "0", "text": [ "weaker" ], "offsets": [ [ 9, 15 ] ], "normalized": [] }, { "id": "15014", "type": "1", "text": [ "chi" ], "offsets": [ [ 13, 16 ] ], "normalized": [] }, { "id": "15015", "type": "2", "text": [ "B" ], "offsets": [ [ 15, 16 ] ], "normalized": [] }, { "id": "15016", "type": "0", "text": [ "complex" ], "offsets": [ [ 23, 30 ] ], "normalized": [] }, { "id": "15017", "type": "0", "text": [ "formation" ], "offsets": [ [ 33, 42 ] ], "normalized": [] }, { "id": "15018", "type": "0", "text": [ "and" ], "offsets": [ [ 37, 40 ] ], "normalized": [] }, { "id": "15019", "type": "0", "text": [ "faster-migrating" ], "offsets": [ [ 54, 70 ] ], "normalized": [] }, { "id": "15020", "type": "0", "text": [ "complexes" ], "offsets": [ [ 64, 73 ] ], "normalized": [] }, { "id": "15021", "type": "0", "text": [ "were" ], "offsets": [ [ 69, 73 ] ], "normalized": [] }, { "id": "15022", "type": "0", "text": [ "detected" ], "offsets": [ [ 78, 86 ] ], "normalized": [] }, { "id": "15023", "type": "0", "text": [ "in" ], "offsets": [ [ 81, 83 ] ], "normalized": [] }, { "id": "15024", "type": "5", "text": [ "non-IL-2-secreting" ], "offsets": [ [ 100, 118 ] ], "normalized": [] }, { "id": "15025", "type": "6", "text": [ "cells" ], "offsets": [ [ 106, 111 ] ], "normalized": [] }, { "id": "15026", "type": "0", "text": [ "." ], "offsets": [ [ 108, 109 ] ], "normalized": [] } ]
[]
[]
[]
15027
NULL
[]
[ { "id": "15028", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "15029", "type": "0", "text": [ "results" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "15030", "type": "0", "text": [ "demonstrate" ], "offsets": [ [ 26, 37 ] ], "normalized": [] }, { "id": "15031", "type": "0", "text": [ "that" ], "offsets": [ [ 31, 35 ] ], "normalized": [] }, { "id": "15032", "type": "0", "text": [ "the" ], "offsets": [ [ 35, 38 ] ], "normalized": [] }, { "id": "15033", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 40, 44 ] ], "normalized": [] }, { "id": "15034", "type": "2", "text": [ "NF-chi" ], "offsets": [ [ 47, 53 ] ], "normalized": [] }, { "id": "15035", "type": "2", "text": [ "B" ], "offsets": [ [ 49, 50 ] ], "normalized": [] }, { "id": "15036", "type": "2", "text": [ "site" ], "offsets": [ [ 54, 58 ] ], "normalized": [] }, { "id": "15037", "type": "0", "text": [ "is" ], "offsets": [ [ 57, 59 ] ], "normalized": [] }, { "id": "15038", "type": "0", "text": [ "indispensable" ], "offsets": [ [ 71, 84 ] ], "normalized": [] }, { "id": "15039", "type": "0", "text": [ "for" ], "offsets": [ [ 75, 78 ] ], "normalized": [] }, { "id": "15040", "type": "0", "text": [ "the" ], "offsets": [ [ 79, 82 ] ], "normalized": [] }, { "id": "15041", "type": "0", "text": [ "activity" ], "offsets": [ [ 88, 96 ] ], "normalized": [] }, { "id": "15042", "type": "0", "text": [ "of" ], "offsets": [ [ 91, 93 ] ], "normalized": [] }, { "id": "15043", "type": "0", "text": [ "the" ], "offsets": [ [ 95, 98 ] ], "normalized": [] }, { "id": "15044", "type": "1", "text": [ "IL-2" ], "offsets": [ [ 100, 104 ] ], "normalized": [] }, { "id": "15045", "type": "2", "text": [ "promoter" ], "offsets": [ [ 109, 117 ] ], "normalized": [] }, { "id": "15046", "type": "0", "text": [ "in" ], "offsets": [ [ 112, 114 ] ], "normalized": [] }, { "id": "15047", "type": "5", "text": [ "EBV-transformed" ], "offsets": [ [ 128, 143 ] ], "normalized": [] }, { "id": "15048", "type": "6", "text": [ "B" ], "offsets": [ [ 130, 131 ] ], "normalized": [] }, { "id": "15049", "type": "6", "text": [ "cells" ], "offsets": [ [ 136, 141 ] ], "normalized": [] }, { "id": "15050", "type": "0", "text": [ "," ], "offsets": [ [ 138, 139 ] ], "normalized": [] }, { "id": "15051", "type": "0", "text": [ "whereas" ], "offsets": [ [ 146, 153 ] ], "normalized": [] }, { "id": "15052", "type": "0", "text": [ "other" ], "offsets": [ [ 152, 157 ] ], "normalized": [] }, { "id": "15053", "type": "9", "text": [ "transcription" ], "offsets": [ [ 166, 179 ] ], "normalized": [] }, { "id": "15054", "type": "10", "text": [ "factors" ], "offsets": [ [ 174, 181 ] ], "normalized": [] }, { "id": "15055", "type": "0", "text": [ "appear" ], "offsets": [ [ 181, 187 ] ], "normalized": [] }, { "id": "15056", "type": "0", "text": [ "to" ], "offsets": [ [ 184, 186 ] ], "normalized": [] }, { "id": "15057", "type": "0", "text": [ "be" ], "offsets": [ [ 187, 189 ] ], "normalized": [] }, { "id": "15058", "type": "0", "text": [ "less" ], "offsets": [ [ 192, 196 ] ], "normalized": [] }, { "id": "15059", "type": "0", "text": [ "important" ], "offsets": [ [ 202, 211 ] ], "normalized": [] }, { "id": "15060", "type": "0", "text": [ "for" ], "offsets": [ [ 206, 209 ] ], "normalized": [] }, { "id": "15061", "type": "9", "text": [ "IL-2" ], "offsets": [ [ 211, 215 ] ], "normalized": [] }, { "id": "15062", "type": "0", "text": [ "expression" ], "offsets": [ [ 222, 232 ] ], "normalized": [] }, { "id": "15063", "type": "0", "text": [ "in" ], "offsets": [ [ 225, 227 ] ], "normalized": [] }, { "id": "15064", "type": "0", "text": [ "these" ], "offsets": [ [ 231, 236 ] ], "normalized": [] }, { "id": "15065", "type": "0", "text": [ "cells" ], "offsets": [ [ 237, 242 ] ], "normalized": [] }, { "id": "15066", "type": "0", "text": [ "." ], "offsets": [ [ 239, 240 ] ], "normalized": [] } ]
[]
[]
[]
15067
NULL
[]
[ { "id": "15068", "type": "9", "text": [ "Latent" ], "offsets": [ [ 7, 13 ] ], "normalized": [] }, { "id": "15069", "type": "10", "text": [ "membrane" ], "offsets": [ [ 16, 24 ] ], "normalized": [] }, { "id": "15070", "type": "10", "text": [ "protein-1" ], "offsets": [ [ 26, 35 ] ], "normalized": [] }, { "id": "15071", "type": "0", "text": [ "induces" ], "offsets": [ [ 34, 41 ] ], "normalized": [] }, { "id": "15072", "type": "9", "text": [ "cyclin" ], "offsets": [ [ 41, 47 ] ], "normalized": [] }, { "id": "15073", "type": "10", "text": [ "D2" ], "offsets": [ [ 44, 46 ] ], "normalized": [] }, { "id": "15074", "type": "0", "text": [ "expression" ], "offsets": [ [ 55, 65 ] ], "normalized": [] }, { "id": "15075", "type": "0", "text": [ "," ], "offsets": [ [ 57, 58 ] ], "normalized": [] }, { "id": "15076", "type": "9", "text": [ "pRb" ], "offsets": [ [ 61, 64 ] ], "normalized": [] }, { "id": "15077", "type": "0", "text": [ "hyperphosphorylation" ], "offsets": [ [ 82, 102 ] ], "normalized": [] }, { "id": "15078", "type": "0", "text": [ "," ], "offsets": [ [ 84, 85 ] ], "normalized": [] }, { "id": "15079", "type": "0", "text": [ "and" ], "offsets": [ [ 88, 91 ] ], "normalized": [] }, { "id": "15080", "type": "0", "text": [ "loss" ], "offsets": [ [ 93, 97 ] ], "normalized": [] }, { "id": "15081", "type": "0", "text": [ "of" ], "offsets": [ [ 96, 98 ] ], "normalized": [] }, { "id": "15082", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 105, 113 ] ], "normalized": [] }, { "id": "15083", "type": "10", "text": [ "1" ], "offsets": [ [ 107, 108 ] ], "normalized": [] }, { "id": "15084", "type": "0", "text": [ "-mediated" ], "offsets": [ [ 117, 126 ] ], "normalized": [] }, { "id": "15085", "type": "0", "text": [ "growth" ], "offsets": [ [ 124, 130 ] ], "normalized": [] }, { "id": "15086", "type": "0", "text": [ "inhibition" ], "offsets": [ [ 135, 145 ] ], "normalized": [] }, { "id": "15087", "type": "0", "text": [ "in" ], "offsets": [ [ 138, 140 ] ], "normalized": [] }, { "id": "15088", "type": "7", "text": [ "EBV-positive" ], "offsets": [ [ 151, 163 ] ], "normalized": [] }, { "id": "15089", "type": "8", "text": [ "B" ], "offsets": [ [ 153, 154 ] ], "normalized": [] }, { "id": "15090", "type": "8", "text": [ "cells" ], "offsets": [ [ 159, 164 ] ], "normalized": [] }, { "id": "15091", "type": "0", "text": [ "." ], "offsets": [ [ 161, 162 ] ], "normalized": [] } ]
[]
[]
[]
15092
NULL
[]
[ { "id": "15093", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15094", "type": "0", "text": [ "normal" ], "offsets": [ [ 11, 17 ] ], "normalized": [] }, { "id": "15095", "type": "0", "text": [ "cell" ], "offsets": [ [ 16, 20 ] ], "normalized": [] }, { "id": "15096", "type": "0", "text": [ "cycle" ], "offsets": [ [ 22, 27 ] ], "normalized": [] }, { "id": "15097", "type": "0", "text": [ "is" ], "offsets": [ [ 25, 27 ] ], "normalized": [] }, { "id": "15098", "type": "0", "text": [ "regulated" ], "offsets": [ [ 35, 44 ] ], "normalized": [] }, { "id": "15099", "type": "0", "text": [ "by" ], "offsets": [ [ 38, 40 ] ], "normalized": [] }, { "id": "15100", "type": "0", "text": [ "several" ], "offsets": [ [ 46, 53 ] ], "normalized": [] }, { "id": "15101", "type": "0", "text": [ "molecules" ], "offsets": [ [ 56, 65 ] ], "normalized": [] }, { "id": "15102", "type": "0", "text": [ "," ], "offsets": [ [ 58, 59 ] ], "normalized": [] }, { "id": "15103", "type": "0", "text": [ "such" ], "offsets": [ [ 63, 67 ] ], "normalized": [] }, { "id": "15104", "type": "0", "text": [ "as" ], "offsets": [ [ 66, 68 ] ], "normalized": [] }, { "id": "15105", "type": "0", "text": [ "the" ], "offsets": [ [ 70, 73 ] ], "normalized": [] }, { "id": "15106", "type": "9", "text": [ "tumor-suppressor" ], "offsets": [ [ 87, 103 ] ], "normalized": [] }, { "id": "15107", "type": "10", "text": [ "protein" ], "offsets": [ [ 95, 102 ] ], "normalized": [] }, { "id": "15108", "type": "10", "text": [ "pRb" ], "offsets": [ [ 99, 102 ] ], "normalized": [] }, { "id": "15109", "type": "0", "text": [ "," ], "offsets": [ [ 101, 102 ] ], "normalized": [] }, { "id": "15110", "type": "0", "text": [ "the" ], "offsets": [ [ 105, 108 ] ], "normalized": [] }, { "id": "15111", "type": "9", "text": [ "G1" ], "offsets": [ [ 108, 110 ] ], "normalized": [] }, { "id": "15112", "type": "10", "text": [ "cyclins" ], "offsets": [ [ 116, 123 ] ], "normalized": [] }, { "id": "15113", "type": "0", "text": [ "," ], "offsets": [ [ 118, 119 ] ], "normalized": [] }, { "id": "15114", "type": "0", "text": [ "the" ], "offsets": [ [ 122, 125 ] ], "normalized": [] }, { "id": "15115", "type": "9", "text": [ "cyclin-dependent" ], "offsets": [ [ 139, 155 ] ], "normalized": [] }, { "id": "15116", "type": "10", "text": [ "kinases" ], "offsets": [ [ 147, 154 ] ], "normalized": [] }, { "id": "15117", "type": "0", "text": [ "," ], "offsets": [ [ 149, 150 ] ], "normalized": [] }, { "id": "15118", "type": "0", "text": [ "and" ], "offsets": [ [ 153, 156 ] ], "normalized": [] }, { "id": "15119", "type": "0", "text": [ "their" ], "offsets": [ [ 159, 164 ] ], "normalized": [] }, { "id": "15120", "type": "0", "text": [ "inhibitors" ], "offsets": [ [ 170, 180 ] ], "normalized": [] }, { "id": "15121", "type": "0", "text": [ "." ], "offsets": [ [ 172, 173 ] ], "normalized": [] } ]
[]
[]
[]
15122
NULL
[]
[ { "id": "15123", "type": "0", "text": [ "These" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "15124", "type": "0", "text": [ "regulators" ], "offsets": [ [ 17, 27 ] ], "normalized": [] }, { "id": "15125", "type": "0", "text": [ "are" ], "offsets": [ [ 21, 24 ] ], "normalized": [] }, { "id": "15126", "type": "0", "text": [ "targeted" ], "offsets": [ [ 30, 38 ] ], "normalized": [] }, { "id": "15127", "type": "0", "text": [ "by" ], "offsets": [ [ 33, 35 ] ], "normalized": [] }, { "id": "15128", "type": "0", "text": [ "negative" ], "offsets": [ [ 42, 50 ] ], "normalized": [] }, { "id": "15129", "type": "0", "text": [ "growth" ], "offsets": [ [ 49, 55 ] ], "normalized": [] }, { "id": "15130", "type": "0", "text": [ "regulatory" ], "offsets": [ [ 60, 70 ] ], "normalized": [] }, { "id": "15131", "type": "0", "text": [ "signals" ], "offsets": [ [ 68, 75 ] ], "normalized": [] }, { "id": "15132", "type": "0", "text": [ "," ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "15133", "type": "0", "text": [ "such" ], "offsets": [ [ 75, 79 ] ], "normalized": [] }, { "id": "15134", "type": "0", "text": [ "as" ], "offsets": [ [ 78, 80 ] ], "normalized": [] }, { "id": "15135", "type": "0", "text": [ "that" ], "offsets": [ [ 83, 87 ] ], "normalized": [] }, { "id": "15136", "type": "0", "text": [ "provided" ], "offsets": [ [ 92, 100 ] ], "normalized": [] }, { "id": "15137", "type": "0", "text": [ "by" ], "offsets": [ [ 95, 97 ] ], "normalized": [] }, { "id": "15138", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 104, 112 ] ], "normalized": [] }, { "id": "15139", "type": "0", "text": [ "." ], "offsets": [ [ 106, 107 ] ], "normalized": [] } ]
[]
[]
[]
15140
NULL
[]
[ { "id": "15141", "type": "0", "text": [ "Here" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "15142", "type": "0", "text": [ "," ], "offsets": [ [ 7, 8 ] ], "normalized": [] }, { "id": "15143", "type": "0", "text": [ "we" ], "offsets": [ [ 10, 12 ] ], "normalized": [] }, { "id": "15144", "type": "0", "text": [ "show" ], "offsets": [ [ 15, 19 ] ], "normalized": [] }, { "id": "15145", "type": "0", "text": [ "that" ], "offsets": [ [ 20, 24 ] ], "normalized": [] }, { "id": "15146", "type": "0", "text": [ "the" ], "offsets": [ [ 24, 27 ] ], "normalized": [] }, { "id": "15147", "type": "0", "text": [ "presence" ], "offsets": [ [ 33, 41 ] ], "normalized": [] }, { "id": "15148", "type": "0", "text": [ "of" ], "offsets": [ [ 36, 38 ] ], "normalized": [] }, { "id": "15149", "type": "0", "text": [ "either" ], "offsets": [ [ 43, 49 ] ], "normalized": [] }, { "id": "15150", "type": "0", "text": [ "wild-type" ], "offsets": [ [ 53, 62 ] ], "normalized": [] }, { "id": "15151", "type": "0", "text": [ "EBV" ], "offsets": [ [ 57, 60 ] ], "normalized": [] }, { "id": "15152", "type": "0", "text": [ "or" ], "offsets": [ [ 60, 62 ] ], "normalized": [] }, { "id": "15153", "type": "0", "text": [ "its" ], "offsets": [ [ 64, 67 ] ], "normalized": [] }, { "id": "15154", "type": "9", "text": [ "transforming" ], "offsets": [ [ 77, 89 ] ], "normalized": [] }, { "id": "15155", "type": "10", "text": [ "latent" ], "offsets": [ [ 84, 90 ] ], "normalized": [] }, { "id": "15156", "type": "10", "text": [ "membrane" ], "offsets": [ [ 93, 101 ] ], "normalized": [] }, { "id": "15157", "type": "10", "text": [ "protein-1" ], "offsets": [ [ 103, 112 ] ], "normalized": [] }, { "id": "15158", "type": "0", "text": [ "(" ], "offsets": [ [ 105, 106 ] ], "normalized": [] }, { "id": "15159", "type": "9", "text": [ "LMP-1" ], "offsets": [ [ 111, 116 ] ], "normalized": [] }, { "id": "15160", "type": "0", "text": [ ")" ], "offsets": [ [ 113, 114 ] ], "normalized": [] }, { "id": "15161", "type": "0", "text": [ "results" ], "offsets": [ [ 121, 128 ] ], "normalized": [] }, { "id": "15162", "type": "0", "text": [ "in" ], "offsets": [ [ 124, 126 ] ], "normalized": [] }, { "id": "15163", "type": "0", "text": [ "the" ], "offsets": [ [ 128, 131 ] ], "normalized": [] }, { "id": "15164", "type": "0", "text": [ "loss" ], "offsets": [ [ 133, 137 ] ], "normalized": [] }, { "id": "15165", "type": "0", "text": [ "of" ], "offsets": [ [ 136, 138 ] ], "normalized": [] }, { "id": "15166", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 145, 153 ] ], "normalized": [] }, { "id": "15167", "type": "10", "text": [ "1" ], "offsets": [ [ 147, 148 ] ], "normalized": [] }, { "id": "15168", "type": "0", "text": [ "-mediated" ], "offsets": [ [ 157, 166 ] ], "normalized": [] }, { "id": "15169", "type": "0", "text": [ "growth" ], "offsets": [ [ 164, 170 ] ], "normalized": [] }, { "id": "15170", "type": "0", "text": [ "inhibition" ], "offsets": [ [ 175, 185 ] ], "normalized": [] }, { "id": "15171", "type": "0", "text": [ "in" ], "offsets": [ [ 178, 180 ] ], "normalized": [] }, { "id": "15172", "type": "7", "text": [ "human" ], "offsets": [ [ 184, 189 ] ], "normalized": [] }, { "id": "15173", "type": "8", "text": [ "B" ], "offsets": [ [ 186, 187 ] ], "normalized": [] }, { "id": "15174", "type": "8", "text": [ "cells" ], "offsets": [ [ 192, 197 ] ], "normalized": [] }, { "id": "15175", "type": "0", "text": [ "." ], "offsets": [ [ 194, 195 ] ], "normalized": [] } ]
[]
[]
[]
15176
NULL
[]
[ { "id": "15177", "type": "0", "text": [ "Chemical" ], "offsets": [ [ 9, 17 ] ], "normalized": [] }, { "id": "15178", "type": "0", "text": [ "cross-linking" ], "offsets": [ [ 23, 36 ] ], "normalized": [] }, { "id": "15179", "type": "0", "text": [ "with" ], "offsets": [ [ 28, 32 ] ], "normalized": [] }, { "id": "15180", "type": "9", "text": [ "125I-labeled" ], "offsets": [ [ 41, 53 ] ], "normalized": [] }, { "id": "15181", "type": "10", "text": [ "TGF-beta" ], "offsets": [ [ 50, 58 ] ], "normalized": [] }, { "id": "15182", "type": "10", "text": [ "1" ], "offsets": [ [ 52, 53 ] ], "normalized": [] }, { "id": "15183", "type": "0", "text": [ "showed" ], "offsets": [ [ 59, 65 ] ], "normalized": [] }, { "id": "15184", "type": "0", "text": [ "an" ], "offsets": [ [ 62, 64 ] ], "normalized": [] }, { "id": "15185", "type": "0", "text": [ "essentially" ], "offsets": [ [ 74, 85 ] ], "normalized": [] }, { "id": "15186", "type": "0", "text": [ "normal" ], "offsets": [ [ 81, 87 ] ], "normalized": [] }, { "id": "15187", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 90, 98 ] ], "normalized": [] }, { "id": "15188", "type": "10", "text": [ "receptor" ], "offsets": [ [ 99, 107 ] ], "normalized": [] }, { "id": "15189", "type": "0", "text": [ "profile" ], "offsets": [ [ 107, 114 ] ], "normalized": [] }, { "id": "15190", "type": "0", "text": [ "in" ], "offsets": [ [ 110, 112 ] ], "normalized": [] }, { "id": "15191", "type": "5", "text": [ "EBV-positive" ], "offsets": [ [ 123, 135 ] ], "normalized": [] }, { "id": "15192", "type": "6", "text": [ "and" ], "offsets": [ [ 127, 130 ] ], "normalized": [] }, { "id": "15193", "type": "6", "text": [ "EBV-negative" ], "offsets": [ [ 140, 152 ] ], "normalized": [] }, { "id": "15194", "type": "6", "text": [ "Burkitt" ], "offsets": [ [ 148, 155 ] ], "normalized": [] }, { "id": "15195", "type": "6", "text": [ "'s" ], "offsets": [ [ 151, 153 ] ], "normalized": [] }, { "id": "15196", "type": "6", "text": [ "lymphoma" ], "offsets": [ [ 160, 168 ] ], "normalized": [] }, { "id": "15197", "type": "6", "text": [ "cell" ], "offsets": [ [ 165, 169 ] ], "normalized": [] }, { "id": "15198", "type": "6", "text": [ "lines" ], "offsets": [ [ 171, 176 ] ], "normalized": [] }, { "id": "15199", "type": "0", "text": [ "," ], "offsets": [ [ 173, 174 ] ], "normalized": [] }, { "id": "15200", "type": "0", "text": [ "and" ], "offsets": [ [ 177, 180 ] ], "normalized": [] }, { "id": "15201", "type": "0", "text": [ "these" ], "offsets": [ [ 183, 188 ] ], "normalized": [] }, { "id": "15202", "type": "0", "text": [ "receptors" ], "offsets": [ [ 193, 202 ] ], "normalized": [] }, { "id": "15203", "type": "0", "text": [ "were" ], "offsets": [ [ 198, 202 ] ], "normalized": [] }, { "id": "15204", "type": "0", "text": [ "shown" ], "offsets": [ [ 204, 209 ] ], "normalized": [] }, { "id": "15205", "type": "0", "text": [ "to" ], "offsets": [ [ 207, 209 ] ], "normalized": [] }, { "id": "15206", "type": "0", "text": [ "be" ], "offsets": [ [ 210, 212 ] ], "normalized": [] }, { "id": "15207", "type": "0", "text": [ "functional" ], "offsets": [ [ 221, 231 ] ], "normalized": [] }, { "id": "15208", "type": "0", "text": [ "in" ], "offsets": [ [ 224, 226 ] ], "normalized": [] }, { "id": "15209", "type": "0", "text": [ "transducing" ], "offsets": [ [ 236, 247 ] ], "normalized": [] }, { "id": "15210", "type": "0", "text": [ "signals" ], "offsets": [ [ 244, 251 ] ], "normalized": [] }, { "id": "15211", "type": "0", "text": [ "," ], "offsets": [ [ 246, 247 ] ], "normalized": [] }, { "id": "15212", "type": "0", "text": [ "as" ], "offsets": [ [ 249, 251 ] ], "normalized": [] }, { "id": "15213", "type": "0", "text": [ "evidenced" ], "offsets": [ [ 259, 268 ] ], "normalized": [] }, { "id": "15214", "type": "0", "text": [ "by" ], "offsets": [ [ 262, 264 ] ], "normalized": [] }, { "id": "15215", "type": "0", "text": [ "the" ], "offsets": [ [ 266, 269 ] ], "normalized": [] }, { "id": "15216", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 275, 283 ] ], "normalized": [] }, { "id": "15217", "type": "10", "text": [ "1" ], "offsets": [ [ 277, 278 ] ], "normalized": [] }, { "id": "15218", "type": "0", "text": [ "-mediated" ], "offsets": [ [ 287, 296 ] ], "normalized": [] }, { "id": "15219", "type": "0", "text": [ "modulation" ], "offsets": [ [ 298, 308 ] ], "normalized": [] }, { "id": "15220", "type": "0", "text": [ "of" ], "offsets": [ [ 301, 303 ] ], "normalized": [] }, { "id": "15221", "type": "1", "text": [ "junB" ], "offsets": [ [ 306, 310 ] ], "normalized": [] }, { "id": "15222", "type": "2", "text": [ "gene" ], "offsets": [ [ 311, 315 ] ], "normalized": [] }, { "id": "15223", "type": "0", "text": [ "expression" ], "offsets": [ [ 322, 332 ] ], "normalized": [] }, { "id": "15224", "type": "0", "text": [ "." ], "offsets": [ [ 324, 325 ] ], "normalized": [] } ]
[]
[]
[]
15225
NULL
[]
[ { "id": "15226", "type": "0", "text": [ "However" ], "offsets": [ [ 8, 15 ] ], "normalized": [] }, { "id": "15227", "type": "0", "text": [ "," ], "offsets": [ [ 10, 11 ] ], "normalized": [] }, { "id": "15228", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 19, 27 ] ], "normalized": [] }, { "id": "15229", "type": "10", "text": [ "1" ], "offsets": [ [ 21, 22 ] ], "normalized": [] }, { "id": "15230", "type": "0", "text": [ "did" ], "offsets": [ [ 25, 28 ] ], "normalized": [] }, { "id": "15231", "type": "0", "text": [ "not" ], "offsets": [ [ 29, 32 ] ], "normalized": [] }, { "id": "15232", "type": "0", "text": [ "induce" ], "offsets": [ [ 36, 42 ] ], "normalized": [] }, { "id": "15233", "type": "0", "text": [ "dephosphorylation" ], "offsets": [ [ 54, 71 ] ], "normalized": [] }, { "id": "15234", "type": "0", "text": [ "of" ], "offsets": [ [ 57, 59 ] ], "normalized": [] }, { "id": "15235", "type": "9", "text": [ "pRb" ], "offsets": [ [ 61, 64 ] ], "normalized": [] }, { "id": "15236", "type": "0", "text": [ "in" ], "offsets": [ [ 64, 66 ] ], "normalized": [] }, { "id": "15237", "type": "5", "text": [ "EBV" ], "offsets": [ [ 68, 71 ] ], "normalized": [] }, { "id": "15238", "type": "6", "text": [ "(" ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "15239", "type": "6", "text": [ "or" ], "offsets": [ [ 73, 75 ] ], "normalized": [] }, { "id": "15240", "type": "6", "text": [ "LMP-1" ], "offsets": [ [ 79, 84 ] ], "normalized": [] }, { "id": "15241", "type": "6", "text": [ ")" ], "offsets": [ [ 81, 82 ] ], "normalized": [] }, { "id": "15242", "type": "6", "text": [ "-positive" ], "offsets": [ [ 91, 100 ] ], "normalized": [] }, { "id": "15243", "type": "6", "text": [ "cells" ], "offsets": [ [ 97, 102 ] ], "normalized": [] }, { "id": "15244", "type": "0", "text": [ "as" ], "offsets": [ [ 100, 102 ] ], "normalized": [] }, { "id": "15245", "type": "0", "text": [ "opposed" ], "offsets": [ [ 108, 115 ] ], "normalized": [] }, { "id": "15246", "type": "0", "text": [ "to" ], "offsets": [ [ 111, 113 ] ], "normalized": [] }, { "id": "15247", "type": "5", "text": [ "EBV-negative" ], "offsets": [ [ 124, 136 ] ], "normalized": [] }, { "id": "15248", "type": "6", "text": [ "cells" ], "offsets": [ [ 130, 135 ] ], "normalized": [] }, { "id": "15249", "type": "0", "text": [ "," ], "offsets": [ [ 132, 133 ] ], "normalized": [] }, { "id": "15250", "type": "0", "text": [ "suggesting" ], "offsets": [ [ 143, 153 ] ], "normalized": [] }, { "id": "15251", "type": "0", "text": [ "a" ], "offsets": [ [ 145, 146 ] ], "normalized": [] }, { "id": "15252", "type": "0", "text": [ "dichotomy" ], "offsets": [ [ 155, 164 ] ], "normalized": [] }, { "id": "15253", "type": "0", "text": [ "in" ], "offsets": [ [ 158, 160 ] ], "normalized": [] }, { "id": "15254", "type": "0", "text": [ "the" ], "offsets": [ [ 162, 165 ] ], "normalized": [] }, { "id": "15255", "type": "9", "text": [ "TGF-beta" ], "offsets": [ [ 171, 179 ] ], "normalized": [] }, { "id": "15256", "type": "10", "text": [ "1" ], "offsets": [ [ 173, 174 ] ], "normalized": [] }, { "id": "15257", "type": "0", "text": [ "signaling" ], "offsets": [ [ 183, 192 ] ], "normalized": [] }, { "id": "15258", "type": "0", "text": [ "pathway" ], "offsets": [ [ 191, 198 ] ], "normalized": [] }, { "id": "15259", "type": "0", "text": [ "leading" ], "offsets": [ [ 199, 206 ] ], "normalized": [] }, { "id": "15260", "type": "0", "text": [ "to" ], "offsets": [ [ 202, 204 ] ], "normalized": [] }, { "id": "15261", "type": "0", "text": [ "separable" ], "offsets": [ [ 212, 221 ] ], "normalized": [] }, { "id": "15262", "type": "0", "text": [ "gene" ], "offsets": [ [ 217, 221 ] ], "normalized": [] }, { "id": "15263", "type": "0", "text": [ "regulatory" ], "offsets": [ [ 228, 238 ] ], "normalized": [] }, { "id": "15264", "type": "0", "text": [ "and" ], "offsets": [ [ 232, 235 ] ], "normalized": [] }, { "id": "15265", "type": "0", "text": [ "growth" ], "offsets": [ [ 239, 245 ] ], "normalized": [] }, { "id": "15266", "type": "0", "text": [ "inhibitory" ], "offsets": [ [ 250, 260 ] ], "normalized": [] }, { "id": "15267", "type": "0", "text": [ "responses" ], "offsets": [ [ 260, 269 ] ], "normalized": [] }, { "id": "15268", "type": "0", "text": [ "." ], "offsets": [ [ 262, 263 ] ], "normalized": [] } ]
[]
[]
[]
15269
NULL
[]
[ { "id": "15270", "type": "0", "text": [ "Furthermore" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "15271", "type": "0", "text": [ "," ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "15272", "type": "9", "text": [ "LMP-1" ], "offsets": [ [ 20, 25 ] ], "normalized": [] }, { "id": "15273", "type": "0", "text": [ "was" ], "offsets": [ [ 24, 27 ] ], "normalized": [] }, { "id": "15274", "type": "0", "text": [ "found" ], "offsets": [ [ 30, 35 ] ], "normalized": [] }, { "id": "15275", "type": "0", "text": [ "to" ], "offsets": [ [ 33, 35 ] ], "normalized": [] }, { "id": "15276", "type": "0", "text": [ "induce" ], "offsets": [ [ 40, 46 ] ], "normalized": [] }, { "id": "15277", "type": "0", "text": [ "the" ], "offsets": [ [ 44, 47 ] ], "normalized": [] }, { "id": "15278", "type": "0", "text": [ "expression" ], "offsets": [ [ 55, 65 ] ], "normalized": [] }, { "id": "15279", "type": "0", "text": [ "of" ], "offsets": [ [ 58, 60 ] ], "normalized": [] }, { "id": "15280", "type": "9", "text": [ "cyclin" ], "offsets": [ [ 65, 71 ] ], "normalized": [] }, { "id": "15281", "type": "10", "text": [ "D2" ], "offsets": [ [ 68, 70 ] ], "normalized": [] }, { "id": "15282", "type": "0", "text": [ ";" ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "15283", "type": "0", "text": [ "normal" ], "offsets": [ [ 77, 83 ] ], "normalized": [] }, { "id": "15284", "type": "7", "text": [ "B" ], "offsets": [ [ 79, 80 ] ], "normalized": [] }, { "id": "15285", "type": "8", "text": [ "cells" ], "offsets": [ [ 85, 90 ] ], "normalized": [] }, { "id": "15286", "type": "0", "text": [ "or" ], "offsets": [ [ 88, 90 ] ], "normalized": [] }, { "id": "15287", "type": "5", "text": [ "EBV-negative" ], "offsets": [ [ 101, 113 ] ], "normalized": [] }, { "id": "15288", "type": "6", "text": [ "Burkitt" ], "offsets": [ [ 109, 116 ] ], "normalized": [] }, { "id": "15289", "type": "6", "text": [ "'s" ], "offsets": [ [ 112, 114 ] ], "normalized": [] }, { "id": "15290", "type": "6", "text": [ "lymphoma" ], "offsets": [ [ 121, 129 ] ], "normalized": [] }, { "id": "15291", "type": "6", "text": [ "cells" ], "offsets": [ [ 127, 132 ] ], "normalized": [] }, { "id": "15292", "type": "0", "text": [ "do" ], "offsets": [ [ 130, 132 ] ], "normalized": [] }, { "id": "15293", "type": "0", "text": [ "not" ], "offsets": [ [ 134, 137 ] ], "normalized": [] }, { "id": "15294", "type": "0", "text": [ "express" ], "offsets": [ [ 142, 149 ] ], "normalized": [] }, { "id": "15295", "type": "9", "text": [ "D-type" ], "offsets": [ [ 149, 155 ] ], "normalized": [] }, { "id": "15296", "type": "10", "text": [ "cyclins" ], "offsets": [ [ 157, 164 ] ], "normalized": [] }, { "id": "15297", "type": "0", "text": [ "." ], "offsets": [ [ 159, 160 ] ], "normalized": [] } ]
[]
[]
[]
15298
NULL
[]
[ { "id": "15299", "type": "0", "text": [ "Taken" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "15300", "type": "0", "text": [ "together" ], "offsets": [ [ 15, 23 ] ], "normalized": [] }, { "id": "15301", "type": "0", "text": [ "," ], "offsets": [ [ 17, 18 ] ], "normalized": [] }, { "id": "15302", "type": "0", "text": [ "these" ], "offsets": [ [ 23, 28 ] ], "normalized": [] }, { "id": "15303", "type": "0", "text": [ "data" ], "offsets": [ [ 28, 32 ] ], "normalized": [] }, { "id": "15304", "type": "0", "text": [ "point" ], "offsets": [ [ 34, 39 ] ], "normalized": [] }, { "id": "15305", "type": "0", "text": [ "to" ], "offsets": [ [ 37, 39 ] ], "normalized": [] }, { "id": "15306", "type": "0", "text": [ "a" ], "offsets": [ [ 39, 40 ] ], "normalized": [] }, { "id": "15307", "type": "0", "text": [ "potential" ], "offsets": [ [ 49, 58 ] ], "normalized": [] }, { "id": "15308", "type": "0", "text": [ "mechanism" ], "offsets": [ [ 59, 68 ] ], "normalized": [] }, { "id": "15309", "type": "0", "text": [ "underlying" ], "offsets": [ [ 70, 80 ] ], "normalized": [] }, { "id": "15310", "type": "0", "text": [ "EBV-mediated" ], "offsets": [ [ 83, 95 ] ], "normalized": [] }, { "id": "15311", "type": "0", "text": [ "B" ], "offsets": [ [ 85, 86 ] ], "normalized": [] }, { "id": "15312", "type": "0", "text": [ "cell" ], "offsets": [ [ 90, 94 ] ], "normalized": [] }, { "id": "15313", "type": "0", "text": [ "transformation" ], "offsets": [ [ 105, 119 ] ], "normalized": [] }, { "id": "15314", "type": "0", "text": [ "whereby" ], "offsets": [ [ 113, 120 ] ], "normalized": [] }, { "id": "15315", "type": "0", "text": [ "constitutive" ], "offsets": [ [ 126, 138 ] ], "normalized": [] }, { "id": "15316", "type": "0", "text": [ "induction" ], "offsets": [ [ 136, 145 ] ], "normalized": [] }, { "id": "15317", "type": "0", "text": [ "of" ], "offsets": [ [ 139, 141 ] ], "normalized": [] }, { "id": "15318", "type": "9", "text": [ "key" ], "offsets": [ [ 143, 146 ] ], "normalized": [] }, { "id": "15319", "type": "10", "text": [ "cell" ], "offsets": [ [ 148, 152 ] ], "normalized": [] }, { "id": "15320", "type": "10", "text": [ "cycle" ], "offsets": [ [ 154, 159 ] ], "normalized": [] }, { "id": "15321", "type": "10", "text": [ "regulators" ], "offsets": [ [ 165, 175 ] ], "normalized": [] }, { "id": "15322", "type": "0", "text": [ "by" ], "offsets": [ [ 168, 170 ] ], "normalized": [] }, { "id": "15323", "type": "9", "text": [ "LMP-1" ], "offsets": [ [ 174, 179 ] ], "normalized": [] }, { "id": "15324", "type": "0", "text": [ "can" ], "offsets": [ [ 178, 181 ] ], "normalized": [] }, { "id": "15325", "type": "0", "text": [ "lead" ], "offsets": [ [ 183, 187 ] ], "normalized": [] }, { "id": "15326", "type": "0", "text": [ "to" ], "offsets": [ [ 186, 188 ] ], "normalized": [] }, { "id": "15327", "type": "9", "text": [ "pRb" ], "offsets": [ [ 190, 193 ] ], "normalized": [] }, { "id": "15328", "type": "0", "text": [ "hyperphosphorylation" ], "offsets": [ [ 211, 231 ] ], "normalized": [] }, { "id": "15329", "type": "0", "text": [ "and" ], "offsets": [ [ 215, 218 ] ], "normalized": [] }, { "id": "15330", "type": "0", "text": [ "uncontrolled" ], "offsets": [ [ 228, 240 ] ], "normalized": [] }, { "id": "15331", "type": "0", "text": [ "cell" ], "offsets": [ [ 233, 237 ] ], "normalized": [] }, { "id": "15332", "type": "0", "text": [ "proliferation" ], "offsets": [ [ 247, 260 ] ], "normalized": [] }, { "id": "15333", "type": "0", "text": [ "." ], "offsets": [ [ 249, 250 ] ], "normalized": [] } ]
[]
[]
[]
15334
NULL
[]
[ { "id": "15335", "type": "0", "text": [ "Does" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "15336", "type": "0", "text": [ "thyroidectomy" ], "offsets": [ [ 19, 32 ] ], "normalized": [] }, { "id": "15337", "type": "0", "text": [ "," ], "offsets": [ [ 21, 22 ] ], "normalized": [] }, { "id": "15338", "type": "0", "text": [ "radioactive" ], "offsets": [ [ 33, 44 ] ], "normalized": [] }, { "id": "15339", "type": "0", "text": [ "iodine" ], "offsets": [ [ 40, 46 ] ], "normalized": [] }, { "id": "15340", "type": "0", "text": [ "therapy" ], "offsets": [ [ 48, 55 ] ], "normalized": [] }, { "id": "15341", "type": "0", "text": [ "," ], "offsets": [ [ 50, 51 ] ], "normalized": [] }, { "id": "15342", "type": "0", "text": [ "or" ], "offsets": [ [ 53, 55 ] ], "normalized": [] }, { "id": "15343", "type": "0", "text": [ "antithyroid" ], "offsets": [ [ 65, 76 ] ], "normalized": [] }, { "id": "15344", "type": "0", "text": [ "drug" ], "offsets": [ [ 70, 74 ] ], "normalized": [] }, { "id": "15345", "type": "0", "text": [ "treatment" ], "offsets": [ [ 80, 89 ] ], "normalized": [] }, { "id": "15346", "type": "0", "text": [ "alter" ], "offsets": [ [ 86, 91 ] ], "normalized": [] }, { "id": "15347", "type": "0", "text": [ "reactivity" ], "offsets": [ [ 97, 107 ] ], "normalized": [] }, { "id": "15348", "type": "0", "text": [ "of" ], "offsets": [ [ 100, 102 ] ], "normalized": [] }, { "id": "15349", "type": "0", "text": [ "patients" ], "offsets": [ [ 109, 117 ] ], "normalized": [] }, { "id": "15350", "type": "0", "text": [ "'" ], "offsets": [ [ 111, 112 ] ], "normalized": [] }, { "id": "15351", "type": "7", "text": [ "T" ], "offsets": [ [ 113, 114 ] ], "normalized": [] }, { "id": "15352", "type": "8", "text": [ "cells" ], "offsets": [ [ 119, 124 ] ], "normalized": [] }, { "id": "15353", "type": "0", "text": [ "to" ], "offsets": [ [ 122, 124 ] ], "normalized": [] }, { "id": "15354", "type": "0", "text": [ "epitopes" ], "offsets": [ [ 131, 139 ] ], "normalized": [] }, { "id": "15355", "type": "0", "text": [ "of" ], "offsets": [ [ 134, 136 ] ], "normalized": [] }, { "id": "15356", "type": "9", "text": [ "thyrotropin" ], "offsets": [ [ 146, 157 ] ], "normalized": [] }, { "id": "15357", "type": "10", "text": [ "receptor" ], "offsets": [ [ 155, 163 ] ], "normalized": [] }, { "id": "15358", "type": "0", "text": [ "in" ], "offsets": [ [ 158, 160 ] ], "normalized": [] }, { "id": "15359", "type": "0", "text": [ "autoimmune" ], "offsets": [ [ 169, 179 ] ], "normalized": [] }, { "id": "15360", "type": "0", "text": [ "thyroid" ], "offsets": [ [ 177, 184 ] ], "normalized": [] }, { "id": "15361", "type": "0", "text": [ "diseases" ], "offsets": [ [ 186, 194 ] ], "normalized": [] }, { "id": "15362", "type": "0", "text": [ "?" ], "offsets": [ [ 188, 189 ] ], "normalized": [] } ]
[]
[]
[]
15363
NULL
[]
[ { "id": "15364", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15365", "type": "0", "text": [ "effect" ], "offsets": [ [ 11, 17 ] ], "normalized": [] }, { "id": "15366", "type": "0", "text": [ "of" ], "offsets": [ [ 14, 16 ] ], "normalized": [] }, { "id": "15367", "type": "0", "text": [ "treatment" ], "offsets": [ [ 24, 33 ] ], "normalized": [] }, { "id": "15368", "type": "0", "text": [ "on" ], "offsets": [ [ 27, 29 ] ], "normalized": [] }, { "id": "15369", "type": "0", "text": [ "thyroid" ], "offsets": [ [ 35, 42 ] ], "normalized": [] }, { "id": "15370", "type": "0", "text": [ "antibody" ], "offsets": [ [ 44, 52 ] ], "normalized": [] }, { "id": "15371", "type": "0", "text": [ "production" ], "offsets": [ [ 55, 65 ] ], "normalized": [] }, { "id": "15372", "type": "0", "text": [ "and" ], "offsets": [ [ 59, 62 ] ], "normalized": [] }, { "id": "15373", "type": "0", "text": [ "T" ], "offsets": [ [ 61, 62 ] ], "normalized": [] }, { "id": "15374", "type": "0", "text": [ "cell" ], "offsets": [ [ 66, 70 ] ], "normalized": [] }, { "id": "15375", "type": "0", "text": [ "reactivity" ], "offsets": [ [ 77, 87 ] ], "normalized": [] }, { "id": "15376", "type": "0", "text": [ "to" ], "offsets": [ [ 80, 82 ] ], "normalized": [] }, { "id": "15377", "type": "0", "text": [ "thyroid" ], "offsets": [ [ 88, 95 ] ], "normalized": [] }, { "id": "15378", "type": "0", "text": [ "antigens" ], "offsets": [ [ 97, 105 ] ], "normalized": [] }, { "id": "15379", "type": "0", "text": [ "was" ], "offsets": [ [ 101, 104 ] ], "normalized": [] }, { "id": "15380", "type": "0", "text": [ "studied" ], "offsets": [ [ 109, 116 ] ], "normalized": [] }, { "id": "15381", "type": "0", "text": [ "in" ], "offsets": [ [ 112, 114 ] ], "normalized": [] }, { "id": "15382", "type": "0", "text": [ "15" ], "offsets": [ [ 115, 117 ] ], "normalized": [] }, { "id": "15383", "type": "0", "text": [ "patients" ], "offsets": [ [ 124, 132 ] ], "normalized": [] }, { "id": "15384", "type": "0", "text": [ "with" ], "offsets": [ [ 129, 133 ] ], "normalized": [] }, { "id": "15385", "type": "0", "text": [ "Graves" ], "offsets": [ [ 136, 142 ] ], "normalized": [] }, { "id": "15386", "type": "0", "text": [ "'" ], "offsets": [ [ 138, 139 ] ], "normalized": [] }, { "id": "15387", "type": "0", "text": [ "disease" ], "offsets": [ [ 146, 153 ] ], "normalized": [] }, { "id": "15388", "type": "0", "text": [ "(" ], "offsets": [ [ 148, 149 ] ], "normalized": [] }, { "id": "15389", "type": "0", "text": [ "GD" ], "offsets": [ [ 151, 153 ] ], "normalized": [] }, { "id": "15390", "type": "0", "text": [ ")" ], "offsets": [ [ 153, 154 ] ], "normalized": [] }, { "id": "15391", "type": "0", "text": [ "before" ], "offsets": [ [ 160, 166 ] ], "normalized": [] }, { "id": "15392", "type": "0", "text": [ "and" ], "offsets": [ [ 164, 167 ] ], "normalized": [] }, { "id": "15393", "type": "0", "text": [ "after" ], "offsets": [ [ 170, 175 ] ], "normalized": [] }, { "id": "15394", "type": "0", "text": [ "thyroidectomy" ], "offsets": [ [ 184, 197 ] ], "normalized": [] }, { "id": "15395", "type": "0", "text": [ "," ], "offsets": [ [ 186, 187 ] ], "normalized": [] }, { "id": "15396", "type": "0", "text": [ "19" ], "offsets": [ [ 189, 191 ] ], "normalized": [] }, { "id": "15397", "type": "0", "text": [ "patients" ], "offsets": [ [ 198, 206 ] ], "normalized": [] }, { "id": "15398", "type": "0", "text": [ "with" ], "offsets": [ [ 203, 207 ] ], "normalized": [] }, { "id": "15399", "type": "0", "text": [ "GD" ], "offsets": [ [ 206, 208 ] ], "normalized": [] }, { "id": "15400", "type": "0", "text": [ "before" ], "offsets": [ [ 213, 219 ] ], "normalized": [] }, { "id": "15401", "type": "0", "text": [ "and" ], "offsets": [ [ 217, 220 ] ], "normalized": [] }, { "id": "15402", "type": "0", "text": [ "after" ], "offsets": [ [ 223, 228 ] ], "normalized": [] }, { "id": "15403", "type": "0", "text": [ "radioactive" ], "offsets": [ [ 235, 246 ] ], "normalized": [] }, { "id": "15404", "type": "0", "text": [ "iodine" ], "offsets": [ [ 242, 248 ] ], "normalized": [] }, { "id": "15405", "type": "0", "text": [ "(" ], "offsets": [ [ 244, 245 ] ], "normalized": [] }, { "id": "15406", "type": "0", "text": [ "RAI" ], "offsets": [ [ 248, 251 ] ], "normalized": [] }, { "id": "15407", "type": "0", "text": [ ")" ], "offsets": [ [ 250, 251 ] ], "normalized": [] }, { "id": "15408", "type": "0", "text": [ "therapy" ], "offsets": [ [ 258, 265 ] ], "normalized": [] }, { "id": "15409", "type": "0", "text": [ "," ], "offsets": [ [ 260, 261 ] ], "normalized": [] }, { "id": "15410", "type": "0", "text": [ "and" ], "offsets": [ [ 264, 267 ] ], "normalized": [] }, { "id": "15411", "type": "0", "text": [ "9" ], "offsets": [ [ 266, 267 ] ], "normalized": [] }, { "id": "15412", "type": "0", "text": [ "patients" ], "offsets": [ [ 275, 283 ] ], "normalized": [] }, { "id": "15413", "type": "0", "text": [ "maintained" ], "offsets": [ [ 286, 296 ] ], "normalized": [] }, { "id": "15414", "type": "0", "text": [ "euthyroid" ], "offsets": [ [ 296, 305 ] ], "normalized": [] }, { "id": "15415", "type": "0", "text": [ "on" ], "offsets": [ [ 299, 301 ] ], "normalized": [] }, { "id": "15416", "type": "0", "text": [ "antithyroid" ], "offsets": [ [ 311, 322 ] ], "normalized": [] }, { "id": "15417", "type": "0", "text": [ "drugs" ], "offsets": [ [ 317, 322 ] ], "normalized": [] }, { "id": "15418", "type": "0", "text": [ "(" ], "offsets": [ [ 319, 320 ] ], "normalized": [] }, { "id": "15419", "type": "0", "text": [ "ATD" ], "offsets": [ [ 323, 326 ] ], "normalized": [] }, { "id": "15420", "type": "0", "text": [ ")" ], "offsets": [ [ 325, 326 ] ], "normalized": [] }, { "id": "15421", "type": "0", "text": [ "." ], "offsets": [ [ 327, 328 ] ], "normalized": [] } ]
[]
[]
[]
15422
NULL
[]
[ { "id": "15423", "type": "0", "text": [ "Twenty" ], "offsets": [ [ 7, 13 ] ], "normalized": [] }, { "id": "15424", "type": "0", "text": [ "subjects" ], "offsets": [ [ 16, 24 ] ], "normalized": [] }, { "id": "15425", "type": "0", "text": [ "matched" ], "offsets": [ [ 24, 31 ] ], "normalized": [] }, { "id": "15426", "type": "0", "text": [ "for" ], "offsets": [ [ 28, 31 ] ], "normalized": [] }, { "id": "15427", "type": "0", "text": [ "age" ], "offsets": [ [ 32, 35 ] ], "normalized": [] }, { "id": "15428", "type": "0", "text": [ "and" ], "offsets": [ [ 36, 39 ] ], "normalized": [] }, { "id": "15429", "type": "0", "text": [ "sex" ], "offsets": [ [ 40, 43 ] ], "normalized": [] }, { "id": "15430", "type": "0", "text": [ "without" ], "offsets": [ [ 48, 55 ] ], "normalized": [] }, { "id": "15431", "type": "0", "text": [ "known" ], "offsets": [ [ 54, 59 ] ], "normalized": [] }, { "id": "15432", "type": "0", "text": [ "thyroid" ], "offsets": [ [ 62, 69 ] ], "normalized": [] }, { "id": "15433", "type": "0", "text": [ "disease" ], "offsets": [ [ 70, 77 ] ], "normalized": [] }, { "id": "15434", "type": "0", "text": [ "served" ], "offsets": [ [ 77, 83 ] ], "normalized": [] }, { "id": "15435", "type": "0", "text": [ "as" ], "offsets": [ [ 80, 82 ] ], "normalized": [] }, { "id": "15436", "type": "0", "text": [ "controls" ], "offsets": [ [ 89, 97 ] ], "normalized": [] }, { "id": "15437", "type": "0", "text": [ "." ], "offsets": [ [ 91, 92 ] ], "normalized": [] } ]
[]
[]
[]
15438
NULL
[]
[ { "id": "15439", "type": "0", "text": [ "In" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "15440", "type": "0", "text": [ "GD" ], "offsets": [ [ 6, 8 ] ], "normalized": [] }, { "id": "15441", "type": "0", "text": [ "patients" ], "offsets": [ [ 15, 23 ] ], "normalized": [] }, { "id": "15442", "type": "0", "text": [ "," ], "offsets": [ [ 17, 18 ] ], "normalized": [] }, { "id": "15443", "type": "0", "text": [ "the" ], "offsets": [ [ 21, 24 ] ], "normalized": [] }, { "id": "15444", "type": "0", "text": [ "responses" ], "offsets": [ [ 31, 40 ] ], "normalized": [] }, { "id": "15445", "type": "0", "text": [ "of" ], "offsets": [ [ 34, 36 ] ], "normalized": [] }, { "id": "15446", "type": "7", "text": [ "peripheral" ], "offsets": [ [ 45, 55 ] ], "normalized": [] }, { "id": "15447", "type": "8", "text": [ "blood" ], "offsets": [ [ 51, 56 ] ], "normalized": [] }, { "id": "15448", "type": "8", "text": [ "mononuclear" ], "offsets": [ [ 63, 74 ] ], "normalized": [] }, { "id": "15449", "type": "8", "text": [ "cells" ], "offsets": [ [ 69, 74 ] ], "normalized": [] }, { "id": "15450", "type": "0", "text": [ "(" ], "offsets": [ [ 71, 72 ] ], "normalized": [] }, { "id": "15451", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 76, 80 ] ], "normalized": [] }, { "id": "15452", "type": "0", "text": [ ")" ], "offsets": [ [ 78, 79 ] ], "normalized": [] }, { "id": "15453", "type": "0", "text": [ "and" ], "offsets": [ [ 82, 85 ] ], "normalized": [] }, { "id": "15454", "type": "5", "text": [ "TSH" ], "offsets": [ [ 86, 89 ] ], "normalized": [] }, { "id": "15455", "type": "6", "text": [ "receptor" ], "offsets": [ [ 95, 103 ] ], "normalized": [] }, { "id": "15456", "type": "6", "text": [ "(" ], "offsets": [ [ 97, 98 ] ], "normalized": [] }, { "id": "15457", "type": "6", "text": [ "TSHR" ], "offsets": [ [ 102, 106 ] ], "normalized": [] }, { "id": "15458", "type": "6", "text": [ ")" ], "offsets": [ [ 104, 105 ] ], "normalized": [] }, { "id": "15459", "type": "6", "text": [ "-specific" ], "offsets": [ [ 114, 123 ] ], "normalized": [] }, { "id": "15460", "type": "6", "text": [ "T" ], "offsets": [ [ 116, 117 ] ], "normalized": [] }, { "id": "15461", "type": "6", "text": [ "cell" ], "offsets": [ [ 121, 125 ] ], "normalized": [] }, { "id": "15462", "type": "6", "text": [ "lines" ], "offsets": [ [ 127, 132 ] ], "normalized": [] }, { "id": "15463", "type": "0", "text": [ "to" ], "offsets": [ [ 130, 132 ] ], "normalized": [] }, { "id": "15464", "type": "9", "text": [ "recombinant" ], "offsets": [ [ 142, 153 ] ], "normalized": [] }, { "id": "15465", "type": "10", "text": [ "human" ], "offsets": [ [ 148, 153 ] ], "normalized": [] }, { "id": "15466", "type": "10", "text": [ "TSHR" ], "offsets": [ [ 153, 157 ] ], "normalized": [] }, { "id": "15467", "type": "10", "text": [ "extracellular" ], "offsets": [ [ 167, 180 ] ], "normalized": [] }, { "id": "15468", "type": "10", "text": [ "domain" ], "offsets": [ [ 174, 180 ] ], "normalized": [] }, { "id": "15469", "type": "0", "text": [ "," ], "offsets": [ [ 176, 177 ] ], "normalized": [] }, { "id": "15470", "type": "9", "text": [ "thyroglobulin" ], "offsets": [ [ 190, 203 ] ], "normalized": [] }, { "id": "15471", "type": "0", "text": [ "," ], "offsets": [ [ 192, 193 ] ], "normalized": [] }, { "id": "15472", "type": "0", "text": [ "and" ], "offsets": [ [ 196, 199 ] ], "normalized": [] }, { "id": "15473", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 201, 205 ] ], "normalized": [] }, { "id": "15474", "type": "0", "text": [ "peptides" ], "offsets": [ [ 210, 218 ] ], "normalized": [] }, { "id": "15475", "type": "0", "text": [ "were" ], "offsets": [ [ 215, 219 ] ], "normalized": [] }, { "id": "15476", "type": "0", "text": [ "examined" ], "offsets": [ [ 224, 232 ] ], "normalized": [] }, { "id": "15477", "type": "0", "text": [ "on" ], "offsets": [ [ 227, 229 ] ], "normalized": [] }, { "id": "15478", "type": "0", "text": [ "the" ], "offsets": [ [ 231, 234 ] ], "normalized": [] }, { "id": "15479", "type": "0", "text": [ "day" ], "offsets": [ [ 235, 238 ] ], "normalized": [] }, { "id": "15480", "type": "0", "text": [ "of" ], "offsets": [ [ 238, 240 ] ], "normalized": [] }, { "id": "15481", "type": "0", "text": [ "surgery" ], "offsets": [ [ 246, 253 ] ], "normalized": [] }, { "id": "15482", "type": "0", "text": [ "or" ], "offsets": [ [ 249, 251 ] ], "normalized": [] }, { "id": "15483", "type": "0", "text": [ "RAI" ], "offsets": [ [ 253, 256 ] ], "normalized": [] }, { "id": "15484", "type": "0", "text": [ "therapy" ], "offsets": [ [ 261, 268 ] ], "normalized": [] }, { "id": "15485", "type": "0", "text": [ "(" ], "offsets": [ [ 263, 264 ] ], "normalized": [] }, { "id": "15486", "type": "0", "text": [ "day" ], "offsets": [ [ 267, 270 ] ], "normalized": [] }, { "id": "15487", "type": "0", "text": [ "0" ], "offsets": [ [ 269, 270 ] ], "normalized": [] }, { "id": "15488", "type": "0", "text": [ ")" ], "offsets": [ [ 271, 272 ] ], "normalized": [] }, { "id": "15489", "type": "0", "text": [ "and" ], "offsets": [ [ 275, 278 ] ], "normalized": [] }, { "id": "15490", "type": "0", "text": [ "also" ], "offsets": [ [ 280, 284 ] ], "normalized": [] }, { "id": "15491", "type": "0", "text": [ "6-8" ], "offsets": [ [ 284, 287 ] ], "normalized": [] }, { "id": "15492", "type": "0", "text": [ "weeks" ], "offsets": [ [ 290, 295 ] ], "normalized": [] }, { "id": "15493", "type": "0", "text": [ "and" ], "offsets": [ [ 294, 297 ] ], "normalized": [] }, { "id": "15494", "type": "0", "text": [ "3-6" ], "offsets": [ [ 298, 301 ] ], "normalized": [] }, { "id": "15495", "type": "0", "text": [ "months" ], "offsets": [ [ 305, 311 ] ], "normalized": [] }, { "id": "15496", "type": "0", "text": [ "thereafter" ], "offsets": [ [ 316, 326 ] ], "normalized": [] }, { "id": "15497", "type": "0", "text": [ "." ], "offsets": [ [ 318, 319 ] ], "normalized": [] } ]
[]
[]
[]
15498
NULL
[]
[ { "id": "15499", "type": "0", "text": [ "Reactivity" ], "offsets": [ [ 11, 21 ] ], "normalized": [] }, { "id": "15500", "type": "0", "text": [ "to" ], "offsets": [ [ 14, 16 ] ], "normalized": [] }, { "id": "15501", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 19, 23 ] ], "normalized": [] }, { "id": "15502", "type": "0", "text": [ "peptides" ], "offsets": [ [ 28, 36 ] ], "normalized": [] }, { "id": "15503", "type": "0", "text": [ "before" ], "offsets": [ [ 35, 41 ] ], "normalized": [] }, { "id": "15504", "type": "0", "text": [ "surgery" ], "offsets": [ [ 43, 50 ] ], "normalized": [] }, { "id": "15505", "type": "0", "text": [ "was" ], "offsets": [ [ 47, 50 ] ], "normalized": [] }, { "id": "15506", "type": "0", "text": [ "heterogeneous" ], "offsets": [ [ 61, 74 ] ], "normalized": [] }, { "id": "15507", "type": "0", "text": [ "and" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "15508", "type": "0", "text": [ "spanned" ], "offsets": [ [ 73, 80 ] ], "normalized": [] }, { "id": "15509", "type": "0", "text": [ "the" ], "offsets": [ [ 77, 80 ] ], "normalized": [] }, { "id": "15510", "type": "0", "text": [ "entire" ], "offsets": [ [ 84, 90 ] ], "normalized": [] }, { "id": "15511", "type": "9", "text": [ "extracellular" ], "offsets": [ [ 98, 111 ] ], "normalized": [] }, { "id": "15512", "type": "10", "text": [ "domain" ], "offsets": [ [ 105, 111 ] ], "normalized": [] }, { "id": "15513", "type": "0", "text": [ "." ], "offsets": [ [ 107, 108 ] ], "normalized": [] } ]
[]
[]
[]
15514
NULL
[]
[ { "id": "15515", "type": "0", "text": [ "Six" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15516", "type": "0", "text": [ "to" ], "offsets": [ [ 7, 9 ] ], "normalized": [] }, { "id": "15517", "type": "0", "text": [ "8" ], "offsets": [ [ 9, 10 ] ], "normalized": [] }, { "id": "15518", "type": "0", "text": [ "weeks" ], "offsets": [ [ 15, 20 ] ], "normalized": [] }, { "id": "15519", "type": "0", "text": [ "after" ], "offsets": [ [ 21, 26 ] ], "normalized": [] }, { "id": "15520", "type": "0", "text": [ "subtotal" ], "offsets": [ [ 30, 38 ] ], "normalized": [] }, { "id": "15521", "type": "0", "text": [ "thyroidectomy" ], "offsets": [ [ 44, 57 ] ], "normalized": [] }, { "id": "15522", "type": "0", "text": [ "," ], "offsets": [ [ 46, 47 ] ], "normalized": [] }, { "id": "15523", "type": "0", "text": [ "the" ], "offsets": [ [ 50, 53 ] ], "normalized": [] }, { "id": "15524", "type": "0", "text": [ "number" ], "offsets": [ [ 57, 63 ] ], "normalized": [] }, { "id": "15525", "type": "0", "text": [ "of" ], "offsets": [ [ 60, 62 ] ], "normalized": [] }, { "id": "15526", "type": "0", "text": [ "patients" ], "offsets": [ [ 69, 77 ] ], "normalized": [] }, { "id": "15527", "type": "0", "text": [ "'" ], "offsets": [ [ 71, 72 ] ], "normalized": [] }, { "id": "15528", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 76, 80 ] ], "normalized": [] }, { "id": "15529", "type": "0", "text": [ "responding" ], "offsets": [ [ 87, 97 ] ], "normalized": [] }, { "id": "15530", "type": "0", "text": [ "to" ], "offsets": [ [ 90, 92 ] ], "normalized": [] }, { "id": "15531", "type": "0", "text": [ "any" ], "offsets": [ [ 94, 97 ] ], "normalized": [] }, { "id": "15532", "type": "0", "text": [ "peptide" ], "offsets": [ [ 102, 109 ] ], "normalized": [] }, { "id": "15533", "type": "0", "text": [ "and" ], "offsets": [ [ 106, 109 ] ], "normalized": [] }, { "id": "15534", "type": "0", "text": [ "the" ], "offsets": [ [ 110, 113 ] ], "normalized": [] }, { "id": "15535", "type": "0", "text": [ "average" ], "offsets": [ [ 118, 125 ] ], "normalized": [] }, { "id": "15536", "type": "0", "text": [ "number" ], "offsets": [ [ 125, 131 ] ], "normalized": [] }, { "id": "15537", "type": "0", "text": [ "of" ], "offsets": [ [ 128, 130 ] ], "normalized": [] }, { "id": "15538", "type": "0", "text": [ "recognized" ], "offsets": [ [ 139, 149 ] ], "normalized": [] }, { "id": "15539", "type": "0", "text": [ "peptides" ], "offsets": [ [ 148, 156 ] ], "normalized": [] }, { "id": "15540", "type": "0", "text": [ "decreased" ], "offsets": [ [ 158, 167 ] ], "normalized": [] }, { "id": "15541", "type": "0", "text": [ "." ], "offsets": [ [ 160, 161 ] ], "normalized": [] } ]
[]
[]
[]
15542
NULL
[]
[ { "id": "15543", "type": "0", "text": [ "A" ], "offsets": [ [ 2, 3 ] ], "normalized": [] }, { "id": "15544", "type": "0", "text": [ "further" ], "offsets": [ [ 10, 17 ] ], "normalized": [] }, { "id": "15545", "type": "0", "text": [ "decrease" ], "offsets": [ [ 19, 27 ] ], "normalized": [] }, { "id": "15546", "type": "0", "text": [ "in" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "15547", "type": "0", "text": [ "the" ], "offsets": [ [ 26, 29 ] ], "normalized": [] }, { "id": "15548", "type": "0", "text": [ "T" ], "offsets": [ [ 28, 29 ] ], "normalized": [] }, { "id": "15549", "type": "0", "text": [ "cell" ], "offsets": [ [ 33, 37 ] ], "normalized": [] }, { "id": "15550", "type": "0", "text": [ "reactivity" ], "offsets": [ [ 44, 54 ] ], "normalized": [] }, { "id": "15551", "type": "0", "text": [ "to" ], "offsets": [ [ 47, 49 ] ], "normalized": [] }, { "id": "15552", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 52, 56 ] ], "normalized": [] }, { "id": "15553", "type": "0", "text": [ "peptides" ], "offsets": [ [ 61, 69 ] ], "normalized": [] }, { "id": "15554", "type": "0", "text": [ "was" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "15555", "type": "0", "text": [ "observed" ], "offsets": [ [ 74, 82 ] ], "normalized": [] }, { "id": "15556", "type": "0", "text": [ "3-6" ], "offsets": [ [ 78, 81 ] ], "normalized": [] }, { "id": "15557", "type": "0", "text": [ "months" ], "offsets": [ [ 85, 91 ] ], "normalized": [] }, { "id": "15558", "type": "0", "text": [ "after" ], "offsets": [ [ 91, 96 ] ], "normalized": [] }, { "id": "15559", "type": "0", "text": [ "surgery" ], "offsets": [ [ 99, 106 ] ], "normalized": [] }, { "id": "15560", "type": "0", "text": [ "." ], "offsets": [ [ 101, 102 ] ], "normalized": [] } ]
[]
[]
[]
15561
NULL
[]
[ { "id": "15562", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15563", "type": "0", "text": [ "responses" ], "offsets": [ [ 14, 23 ] ], "normalized": [] }, { "id": "15564", "type": "0", "text": [ "of" ], "offsets": [ [ 17, 19 ] ], "normalized": [] }, { "id": "15565", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 22, 26 ] ], "normalized": [] }, { "id": "15566", "type": "0", "text": [ "from" ], "offsets": [ [ 27, 31 ] ], "normalized": [] }, { "id": "15567", "type": "0", "text": [ "Graves" ], "offsets": [ [ 34, 40 ] ], "normalized": [] }, { "id": "15568", "type": "0", "text": [ "'" ], "offsets": [ [ 36, 37 ] ], "normalized": [] }, { "id": "15569", "type": "0", "text": [ "patients" ], "offsets": [ [ 45, 53 ] ], "normalized": [] }, { "id": "15570", "type": "0", "text": [ "before" ], "offsets": [ [ 52, 58 ] ], "normalized": [] }, { "id": "15571", "type": "0", "text": [ "RAI" ], "offsets": [ [ 56, 59 ] ], "normalized": [] }, { "id": "15572", "type": "0", "text": [ "therapy" ], "offsets": [ [ 64, 71 ] ], "normalized": [] }, { "id": "15573", "type": "0", "text": [ "were" ], "offsets": [ [ 69, 73 ] ], "normalized": [] }, { "id": "15574", "type": "0", "text": [ "less" ], "offsets": [ [ 74, 78 ] ], "normalized": [] }, { "id": "15575", "type": "0", "text": [ "than" ], "offsets": [ [ 79, 83 ] ], "normalized": [] }, { "id": "15576", "type": "0", "text": [ "those" ], "offsets": [ [ 85, 90 ] ], "normalized": [] }, { "id": "15577", "type": "0", "text": [ "in" ], "offsets": [ [ 88, 90 ] ], "normalized": [] }, { "id": "15578", "type": "0", "text": [ "the" ], "offsets": [ [ 92, 95 ] ], "normalized": [] }, { "id": "15579", "type": "0", "text": [ "presurgical" ], "offsets": [ [ 104, 115 ] ], "normalized": [] }, { "id": "15580", "type": "0", "text": [ "group" ], "offsets": [ [ 110, 115 ] ], "normalized": [] }, { "id": "15581", "type": "0", "text": [ "." ], "offsets": [ [ 112, 113 ] ], "normalized": [] } ]
[]
[]
[]
15582
NULL
[]
[ { "id": "15583", "type": "0", "text": [ "Six" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15584", "type": "0", "text": [ "to" ], "offsets": [ [ 7, 9 ] ], "normalized": [] }, { "id": "15585", "type": "0", "text": [ "8" ], "offsets": [ [ 9, 10 ] ], "normalized": [] }, { "id": "15586", "type": "0", "text": [ "weeks" ], "offsets": [ [ 15, 20 ] ], "normalized": [] }, { "id": "15587", "type": "0", "text": [ "after" ], "offsets": [ [ 21, 26 ] ], "normalized": [] }, { "id": "15588", "type": "0", "text": [ "RAI" ], "offsets": [ [ 25, 28 ] ], "normalized": [] }, { "id": "15589", "type": "0", "text": [ "therapy" ], "offsets": [ [ 33, 40 ] ], "normalized": [] }, { "id": "15590", "type": "0", "text": [ "," ], "offsets": [ [ 35, 36 ] ], "normalized": [] }, { "id": "15591", "type": "0", "text": [ "the" ], "offsets": [ [ 39, 42 ] ], "normalized": [] }, { "id": "15592", "type": "0", "text": [ "number" ], "offsets": [ [ 46, 52 ] ], "normalized": [] }, { "id": "15593", "type": "0", "text": [ "of" ], "offsets": [ [ 49, 51 ] ], "normalized": [] }, { "id": "15594", "type": "0", "text": [ "patients" ], "offsets": [ [ 58, 66 ] ], "normalized": [] }, { "id": "15595", "type": "0", "text": [ "responding" ], "offsets": [ [ 69, 79 ] ], "normalized": [] }, { "id": "15596", "type": "0", "text": [ "to" ], "offsets": [ [ 72, 74 ] ], "normalized": [] }, { "id": "15597", "type": "0", "text": [ "any" ], "offsets": [ [ 76, 79 ] ], "normalized": [] }, { "id": "15598", "type": "0", "text": [ "peptide" ], "offsets": [ [ 84, 91 ] ], "normalized": [] }, { "id": "15599", "type": "0", "text": [ "and" ], "offsets": [ [ 88, 91 ] ], "normalized": [] }, { "id": "15600", "type": "0", "text": [ "the" ], "offsets": [ [ 92, 95 ] ], "normalized": [] }, { "id": "15601", "type": "0", "text": [ "average" ], "offsets": [ [ 100, 107 ] ], "normalized": [] }, { "id": "15602", "type": "0", "text": [ "number" ], "offsets": [ [ 107, 113 ] ], "normalized": [] }, { "id": "15603", "type": "0", "text": [ "of" ], "offsets": [ [ 110, 112 ] ], "normalized": [] }, { "id": "15604", "type": "0", "text": [ "recognized" ], "offsets": [ [ 121, 131 ] ], "normalized": [] }, { "id": "15605", "type": "0", "text": [ "peptides" ], "offsets": [ [ 130, 138 ] ], "normalized": [] }, { "id": "15606", "type": "0", "text": [ "increased" ], "offsets": [ [ 140, 149 ] ], "normalized": [] }, { "id": "15607", "type": "0", "text": [ "." ], "offsets": [ [ 142, 143 ] ], "normalized": [] } ]
[]
[]
[]
15608
NULL
[]
[ { "id": "15609", "type": "0", "text": [ "Three" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "15610", "type": "0", "text": [ "to" ], "offsets": [ [ 9, 11 ] ], "normalized": [] }, { "id": "15611", "type": "0", "text": [ "6" ], "offsets": [ [ 11, 12 ] ], "normalized": [] }, { "id": "15612", "type": "0", "text": [ "months" ], "offsets": [ [ 18, 24 ] ], "normalized": [] }, { "id": "15613", "type": "0", "text": [ "after" ], "offsets": [ [ 24, 29 ] ], "normalized": [] }, { "id": "15614", "type": "0", "text": [ "RAI" ], "offsets": [ [ 28, 31 ] ], "normalized": [] }, { "id": "15615", "type": "0", "text": [ "," ], "offsets": [ [ 30, 31 ] ], "normalized": [] }, { "id": "15616", "type": "0", "text": [ "T" ], "offsets": [ [ 32, 33 ] ], "normalized": [] }, { "id": "15617", "type": "0", "text": [ "cell" ], "offsets": [ [ 37, 41 ] ], "normalized": [] }, { "id": "15618", "type": "0", "text": [ "responses" ], "offsets": [ [ 47, 56 ] ], "normalized": [] }, { "id": "15619", "type": "0", "text": [ "to" ], "offsets": [ [ 50, 52 ] ], "normalized": [] }, { "id": "15620", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 55, 59 ] ], "normalized": [] }, { "id": "15621", "type": "0", "text": [ "peptides" ], "offsets": [ [ 64, 72 ] ], "normalized": [] }, { "id": "15622", "type": "0", "text": [ "were" ], "offsets": [ [ 69, 73 ] ], "normalized": [] }, { "id": "15623", "type": "0", "text": [ "less" ], "offsets": [ [ 74, 78 ] ], "normalized": [] }, { "id": "15624", "type": "0", "text": [ "than" ], "offsets": [ [ 79, 83 ] ], "normalized": [] }, { "id": "15625", "type": "0", "text": [ "those" ], "offsets": [ [ 85, 90 ] ], "normalized": [] }, { "id": "15626", "type": "0", "text": [ "6-8" ], "offsets": [ [ 89, 92 ] ], "normalized": [] }, { "id": "15627", "type": "0", "text": [ "weeks" ], "offsets": [ [ 95, 100 ] ], "normalized": [] }, { "id": "15628", "type": "0", "text": [ "after" ], "offsets": [ [ 101, 106 ] ], "normalized": [] }, { "id": "15629", "type": "0", "text": [ "RAI" ], "offsets": [ [ 105, 108 ] ], "normalized": [] }, { "id": "15630", "type": "0", "text": [ "therapy" ], "offsets": [ [ 113, 120 ] ], "normalized": [] }, { "id": "15631", "type": "0", "text": [ "," ], "offsets": [ [ 115, 116 ] ], "normalized": [] }, { "id": "15632", "type": "0", "text": [ "but" ], "offsets": [ [ 119, 122 ] ], "normalized": [] }, { "id": "15633", "type": "0", "text": [ "still" ], "offsets": [ [ 125, 130 ] ], "normalized": [] }, { "id": "15634", "type": "0", "text": [ "higher" ], "offsets": [ [ 132, 138 ] ], "normalized": [] }, { "id": "15635", "type": "0", "text": [ "than" ], "offsets": [ [ 137, 141 ] ], "normalized": [] }, { "id": "15636", "type": "0", "text": [ "the" ], "offsets": [ [ 141, 144 ] ], "normalized": [] }, { "id": "15637", "type": "0", "text": [ "values" ], "offsets": [ [ 148, 154 ] ], "normalized": [] }, { "id": "15638", "type": "0", "text": [ "on" ], "offsets": [ [ 151, 153 ] ], "normalized": [] }, { "id": "15639", "type": "0", "text": [ "day" ], "offsets": [ [ 155, 158 ] ], "normalized": [] }, { "id": "15640", "type": "0", "text": [ "0" ], "offsets": [ [ 157, 158 ] ], "normalized": [] }, { "id": "15641", "type": "0", "text": [ "." ], "offsets": [ [ 159, 160 ] ], "normalized": [] } ]
[]
[]
[]
15642
NULL
[]
[ { "id": "15643", "type": "0", "text": [ "Responses" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "15644", "type": "0", "text": [ "of" ], "offsets": [ [ 13, 15 ] ], "normalized": [] }, { "id": "15645", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 18, 22 ] ], "normalized": [] }, { "id": "15646", "type": "0", "text": [ "from" ], "offsets": [ [ 23, 27 ] ], "normalized": [] }, { "id": "15647", "type": "0", "text": [ "patients" ], "offsets": [ [ 32, 40 ] ], "normalized": [] }, { "id": "15648", "type": "0", "text": [ "with" ], "offsets": [ [ 37, 41 ] ], "normalized": [] }, { "id": "15649", "type": "0", "text": [ "GD" ], "offsets": [ [ 40, 42 ] ], "normalized": [] }, { "id": "15650", "type": "0", "text": [ "," ], "offsets": [ [ 42, 43 ] ], "normalized": [] }, { "id": "15651", "type": "0", "text": [ "maintained" ], "offsets": [ [ 53, 63 ] ], "normalized": [] }, { "id": "15652", "type": "0", "text": [ "euthyroid" ], "offsets": [ [ 63, 72 ] ], "normalized": [] }, { "id": "15653", "type": "0", "text": [ "on" ], "offsets": [ [ 66, 68 ] ], "normalized": [] }, { "id": "15654", "type": "0", "text": [ "ATD" ], "offsets": [ [ 70, 73 ] ], "normalized": [] }, { "id": "15655", "type": "0", "text": [ "," ], "offsets": [ [ 72, 73 ] ], "normalized": [] }, { "id": "15656", "type": "0", "text": [ "were" ], "offsets": [ [ 77, 81 ] ], "normalized": [] }, { "id": "15657", "type": "0", "text": [ "lower" ], "offsets": [ [ 83, 88 ] ], "normalized": [] }, { "id": "15658", "type": "0", "text": [ "than" ], "offsets": [ [ 88, 92 ] ], "normalized": [] }, { "id": "15659", "type": "0", "text": [ "those" ], "offsets": [ [ 94, 99 ] ], "normalized": [] }, { "id": "15660", "type": "0", "text": [ "before" ], "offsets": [ [ 101, 107 ] ], "normalized": [] }, { "id": "15661", "type": "0", "text": [ "surgery" ], "offsets": [ [ 109, 116 ] ], "normalized": [] }, { "id": "15662", "type": "0", "text": [ "or" ], "offsets": [ [ 112, 114 ] ], "normalized": [] }, { "id": "15663", "type": "0", "text": [ "RAI" ], "offsets": [ [ 116, 119 ] ], "normalized": [] }, { "id": "15664", "type": "0", "text": [ "therapy" ], "offsets": [ [ 124, 131 ] ], "normalized": [] }, { "id": "15665", "type": "0", "text": [ "." ], "offsets": [ [ 126, 127 ] ], "normalized": [] } ]
[]
[]
[]
15666
NULL
[]
[ { "id": "15667", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15668", "type": "0", "text": [ "reactivity" ], "offsets": [ [ 15, 25 ] ], "normalized": [] }, { "id": "15669", "type": "0", "text": [ "of" ], "offsets": [ [ 18, 20 ] ], "normalized": [] }, { "id": "15670", "type": "5", "text": [ "T" ], "offsets": [ [ 20, 21 ] ], "normalized": [] }, { "id": "15671", "type": "6", "text": [ "cell" ], "offsets": [ [ 25, 29 ] ], "normalized": [] }, { "id": "15672", "type": "6", "text": [ "lines" ], "offsets": [ [ 31, 36 ] ], "normalized": [] }, { "id": "15673", "type": "0", "text": [ "in" ], "offsets": [ [ 34, 36 ] ], "normalized": [] }, { "id": "15674", "type": "0", "text": [ "different" ], "offsets": [ [ 44, 53 ] ], "normalized": [] }, { "id": "15675", "type": "0", "text": [ "groups" ], "offsets": [ [ 51, 57 ] ], "normalized": [] }, { "id": "15676", "type": "0", "text": [ "reflected" ], "offsets": [ [ 61, 70 ] ], "normalized": [] }, { "id": "15677", "type": "0", "text": [ "a" ], "offsets": [ [ 63, 64 ] ], "normalized": [] }, { "id": "15678", "type": "0", "text": [ "pattern" ], "offsets": [ [ 71, 78 ] ], "normalized": [] }, { "id": "15679", "type": "0", "text": [ "similar" ], "offsets": [ [ 79, 86 ] ], "normalized": [] }, { "id": "15680", "type": "0", "text": [ "to" ], "offsets": [ [ 82, 84 ] ], "normalized": [] }, { "id": "15681", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 87, 91 ] ], "normalized": [] }, { "id": "15682", "type": "0", "text": [ "after" ], "offsets": [ [ 93, 98 ] ], "normalized": [] }, { "id": "15683", "type": "0", "text": [ "treatment" ], "offsets": [ [ 103, 112 ] ], "normalized": [] }, { "id": "15684", "type": "0", "text": [ "." ], "offsets": [ [ 105, 106 ] ], "normalized": [] } ]
[]
[]
[]
15685
NULL
[]
[ { "id": "15686", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "15687", "type": "10", "text": [ "antibody" ], "offsets": [ [ 14, 22 ] ], "normalized": [] }, { "id": "15688", "type": "0", "text": [ "and" ], "offsets": [ [ 18, 21 ] ], "normalized": [] }, { "id": "15689", "type": "9", "text": [ "microsomal" ], "offsets": [ [ 29, 39 ] ], "normalized": [] }, { "id": "15690", "type": "10", "text": [ "antibody" ], "offsets": [ [ 38, 46 ] ], "normalized": [] }, { "id": "15691", "type": "0", "text": [ "levels" ], "offsets": [ [ 45, 51 ] ], "normalized": [] }, { "id": "15692", "type": "0", "text": [ "decreased" ], "offsets": [ [ 55, 64 ] ], "normalized": [] }, { "id": "15693", "type": "0", "text": [ "after" ], "offsets": [ [ 61, 66 ] ], "normalized": [] }, { "id": "15694", "type": "0", "text": [ "surgery" ], "offsets": [ [ 69, 76 ] ], "normalized": [] }, { "id": "15695", "type": "0", "text": [ "," ], "offsets": [ [ 71, 72 ] ], "normalized": [] }, { "id": "15696", "type": "0", "text": [ "but" ], "offsets": [ [ 75, 78 ] ], "normalized": [] }, { "id": "15697", "type": "0", "text": [ "increased" ], "offsets": [ [ 85, 94 ] ], "normalized": [] }, { "id": "15698", "type": "0", "text": [ "after" ], "offsets": [ [ 91, 96 ] ], "normalized": [] }, { "id": "15699", "type": "0", "text": [ "RAI" ], "offsets": [ [ 95, 98 ] ], "normalized": [] }, { "id": "15700", "type": "0", "text": [ "therapy" ], "offsets": [ [ 103, 110 ] ], "normalized": [] }, { "id": "15701", "type": "0", "text": [ "." ], "offsets": [ [ 105, 106 ] ], "normalized": [] } ]
[]
[]
[]
15702
NULL
[]
[ { "id": "15703", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15704", "type": "0", "text": [ "difference" ], "offsets": [ [ 15, 25 ] ], "normalized": [] }, { "id": "15705", "type": "0", "text": [ "in" ], "offsets": [ [ 18, 20 ] ], "normalized": [] }, { "id": "15706", "type": "0", "text": [ "the" ], "offsets": [ [ 22, 25 ] ], "normalized": [] }, { "id": "15707", "type": "0", "text": [ "number" ], "offsets": [ [ 29, 35 ] ], "normalized": [] }, { "id": "15708", "type": "0", "text": [ "of" ], "offsets": [ [ 32, 34 ] ], "normalized": [] }, { "id": "15709", "type": "0", "text": [ "recognized" ], "offsets": [ [ 43, 53 ] ], "normalized": [] }, { "id": "15710", "type": "0", "text": [ "peptides" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "15711", "type": "0", "text": [ "by" ], "offsets": [ [ 55, 57 ] ], "normalized": [] }, { "id": "15712", "type": "0", "text": [ "patients" ], "offsets": [ [ 64, 72 ] ], "normalized": [] }, { "id": "15713", "type": "0", "text": [ "'" ], "offsets": [ [ 66, 67 ] ], "normalized": [] }, { "id": "15714", "type": "7", "text": [ "PBMC" ], "offsets": [ [ 71, 75 ] ], "normalized": [] }, { "id": "15715", "type": "0", "text": [ "before" ], "offsets": [ [ 78, 84 ] ], "normalized": [] }, { "id": "15716", "type": "0", "text": [ "RAI" ], "offsets": [ [ 82, 85 ] ], "normalized": [] }, { "id": "15717", "type": "0", "text": [ "and" ], "offsets": [ [ 86, 89 ] ], "normalized": [] }, { "id": "15718", "type": "0", "text": [ "surgery" ], "offsets": [ [ 94, 101 ] ], "normalized": [] }, { "id": "15719", "type": "0", "text": [ "may" ], "offsets": [ [ 98, 101 ] ], "normalized": [] }, { "id": "15720", "type": "0", "text": [ "reflect" ], "offsets": [ [ 106, 113 ] ], "normalized": [] }, { "id": "15721", "type": "0", "text": [ "the" ], "offsets": [ [ 110, 113 ] ], "normalized": [] }, { "id": "15722", "type": "0", "text": [ "effect" ], "offsets": [ [ 117, 123 ] ], "normalized": [] }, { "id": "15723", "type": "0", "text": [ "of" ], "offsets": [ [ 120, 122 ] ], "normalized": [] }, { "id": "15724", "type": "0", "text": [ "long" ], "offsets": [ [ 125, 129 ] ], "normalized": [] }, { "id": "15725", "type": "0", "text": [ "term" ], "offsets": [ [ 130, 134 ] ], "normalized": [] }, { "id": "15726", "type": "0", "text": [ "therapy" ], "offsets": [ [ 138, 145 ] ], "normalized": [] }, { "id": "15727", "type": "0", "text": [ "with" ], "offsets": [ [ 143, 147 ] ], "normalized": [] }, { "id": "15728", "type": "0", "text": [ "ATD" ], "offsets": [ [ 147, 150 ] ], "normalized": [] }, { "id": "15729", "type": "0", "text": [ "in" ], "offsets": [ [ 150, 152 ] ], "normalized": [] }, { "id": "15730", "type": "0", "text": [ "the" ], "offsets": [ [ 154, 157 ] ], "normalized": [] }, { "id": "15731", "type": "0", "text": [ "patients" ], "offsets": [ [ 163, 171 ] ], "normalized": [] }, { "id": "15732", "type": "0", "text": [ "before" ], "offsets": [ [ 170, 176 ] ], "normalized": [] }, { "id": "15733", "type": "0", "text": [ "RAI" ], "offsets": [ [ 174, 177 ] ], "normalized": [] }, { "id": "15734", "type": "0", "text": [ "vs." ], "offsets": [ [ 178, 181 ] ], "normalized": [] }, { "id": "15735", "type": "0", "text": [ "the" ], "offsets": [ [ 182, 185 ] ], "normalized": [] }, { "id": "15736", "type": "0", "text": [ "shorter" ], "offsets": [ [ 190, 197 ] ], "normalized": [] }, { "id": "15737", "type": "0", "text": [ "period" ], "offsets": [ [ 197, 203 ] ], "normalized": [] }, { "id": "15738", "type": "0", "text": [ "in" ], "offsets": [ [ 200, 202 ] ], "normalized": [] }, { "id": "15739", "type": "0", "text": [ "patients" ], "offsets": [ [ 209, 217 ] ], "normalized": [] }, { "id": "15740", "type": "0", "text": [ "before" ], "offsets": [ [ 216, 222 ] ], "normalized": [] }, { "id": "15741", "type": "0", "text": [ "surgery" ], "offsets": [ [ 224, 231 ] ], "normalized": [] }, { "id": "15742", "type": "0", "text": [ "." ], "offsets": [ [ 226, 227 ] ], "normalized": [] } ]
[]
[]
[]
15743
NULL
[]
[ { "id": "15744", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15745", "type": "0", "text": [ "decreased" ], "offsets": [ [ 14, 23 ] ], "normalized": [] }, { "id": "15746", "type": "0", "text": [ "T" ], "offsets": [ [ 16, 17 ] ], "normalized": [] }, { "id": "15747", "type": "0", "text": [ "cell" ], "offsets": [ [ 21, 25 ] ], "normalized": [] }, { "id": "15748", "type": "0", "text": [ "reactivity" ], "offsets": [ [ 32, 42 ] ], "normalized": [] }, { "id": "15749", "type": "0", "text": [ "to" ], "offsets": [ [ 35, 37 ] ], "normalized": [] }, { "id": "15750", "type": "9", "text": [ "thyroid" ], "offsets": [ [ 43, 50 ] ], "normalized": [] }, { "id": "15751", "type": "10", "text": [ "antigens" ], "offsets": [ [ 52, 60 ] ], "normalized": [] }, { "id": "15752", "type": "0", "text": [ "after" ], "offsets": [ [ 58, 63 ] ], "normalized": [] }, { "id": "15753", "type": "0", "text": [ "thyroidectomy" ], "offsets": [ [ 72, 85 ] ], "normalized": [] }, { "id": "15754", "type": "0", "text": [ "could" ], "offsets": [ [ 78, 83 ] ], "normalized": [] }, { "id": "15755", "type": "0", "text": [ "be" ], "offsets": [ [ 81, 83 ] ], "normalized": [] }, { "id": "15756", "type": "0", "text": [ "the" ], "offsets": [ [ 85, 88 ] ], "normalized": [] }, { "id": "15757", "type": "0", "text": [ "result" ], "offsets": [ [ 92, 98 ] ], "normalized": [] }, { "id": "15758", "type": "0", "text": [ "of" ], "offsets": [ [ 95, 97 ] ], "normalized": [] }, { "id": "15759", "type": "0", "text": [ "removal" ], "offsets": [ [ 103, 110 ] ], "normalized": [] }, { "id": "15760", "type": "0", "text": [ "of" ], "offsets": [ [ 106, 108 ] ], "normalized": [] }, { "id": "15761", "type": "0", "text": [ "a" ], "offsets": [ [ 108, 109 ] ], "normalized": [] }, { "id": "15762", "type": "0", "text": [ "major" ], "offsets": [ [ 114, 119 ] ], "normalized": [] }, { "id": "15763", "type": "0", "text": [ "part" ], "offsets": [ [ 119, 123 ] ], "normalized": [] }, { "id": "15764", "type": "0", "text": [ "of" ], "offsets": [ [ 122, 124 ] ], "normalized": [] }, { "id": "15765", "type": "0", "text": [ "the" ], "offsets": [ [ 126, 129 ] ], "normalized": [] }, { "id": "15766", "type": "0", "text": [ "thyroid" ], "offsets": [ [ 134, 141 ] ], "normalized": [] }, { "id": "15767", "type": "0", "text": [ "gland" ], "offsets": [ [ 140, 145 ] ], "normalized": [] }, { "id": "15768", "type": "0", "text": [ "or" ], "offsets": [ [ 143, 145 ] ], "normalized": [] }, { "id": "15769", "type": "0", "text": [ "redistribution" ], "offsets": [ [ 158, 172 ] ], "normalized": [] }, { "id": "15770", "type": "0", "text": [ "of" ], "offsets": [ [ 161, 163 ] ], "normalized": [] }, { "id": "15771", "type": "0", "text": [ "suppressor-inducer" ], "offsets": [ [ 180, 198 ] ], "normalized": [] }, { "id": "15772", "type": "7", "text": [ "T" ], "offsets": [ [ 182, 183 ] ], "normalized": [] }, { "id": "15773", "type": "8", "text": [ "cells" ], "offsets": [ [ 188, 193 ] ], "normalized": [] }, { "id": "15774", "type": "0", "text": [ "." ], "offsets": [ [ 190, 191 ] ], "normalized": [] } ]
[]
[]
[]
15775
NULL
[]
[ { "id": "15776", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15777", "type": "0", "text": [ "increased" ], "offsets": [ [ 14, 23 ] ], "normalized": [] }, { "id": "15778", "type": "0", "text": [ "T" ], "offsets": [ [ 16, 17 ] ], "normalized": [] }, { "id": "15779", "type": "0", "text": [ "cell" ], "offsets": [ [ 21, 25 ] ], "normalized": [] }, { "id": "15780", "type": "0", "text": [ "response" ], "offsets": [ [ 30, 38 ] ], "normalized": [] }, { "id": "15781", "type": "0", "text": [ "after" ], "offsets": [ [ 36, 41 ] ], "normalized": [] }, { "id": "15782", "type": "0", "text": [ "RAI" ], "offsets": [ [ 40, 43 ] ], "normalized": [] }, { "id": "15783", "type": "0", "text": [ "therapy" ], "offsets": [ [ 48, 55 ] ], "normalized": [] }, { "id": "15784", "type": "0", "text": [ "is" ], "offsets": [ [ 51, 53 ] ], "normalized": [] }, { "id": "15785", "type": "0", "text": [ "probably" ], "offsets": [ [ 60, 68 ] ], "normalized": [] }, { "id": "15786", "type": "0", "text": [ "epitope" ], "offsets": [ [ 68, 75 ] ], "normalized": [] }, { "id": "15787", "type": "0", "text": [ "specific" ], "offsets": [ [ 77, 85 ] ], "normalized": [] }, { "id": "15788", "type": "0", "text": [ "," ], "offsets": [ [ 79, 80 ] ], "normalized": [] }, { "id": "15789", "type": "0", "text": [ "rather" ], "offsets": [ [ 86, 92 ] ], "normalized": [] }, { "id": "15790", "type": "0", "text": [ "than" ], "offsets": [ [ 91, 95 ] ], "normalized": [] }, { "id": "15791", "type": "0", "text": [ "a" ], "offsets": [ [ 93, 94 ] ], "normalized": [] }, { "id": "15792", "type": "0", "text": [ "response" ], "offsets": [ [ 102, 110 ] ], "normalized": [] }, { "id": "15793", "type": "0", "text": [ "to" ], "offsets": [ [ 105, 107 ] ], "normalized": [] }, { "id": "15794", "type": "0", "text": [ "the" ], "offsets": [ [ 109, 112 ] ], "normalized": [] }, { "id": "15795", "type": "0", "text": [ "whole" ], "offsets": [ [ 115, 120 ] ], "normalized": [] }, { "id": "15796", "type": "9", "text": [ "TSHR" ], "offsets": [ [ 120, 124 ] ], "normalized": [] }, { "id": "15797", "type": "0", "text": [ "molecule" ], "offsets": [ [ 129, 137 ] ], "normalized": [] }, { "id": "15798", "type": "0", "text": [ "." ], "offsets": [ [ 131, 132 ] ], "normalized": [] } ]
[]
[]
[]
15799
NULL
[]
[ { "id": "15800", "type": "0", "text": [ "Synchronous" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "15801", "type": "0", "text": [ "recognition" ], "offsets": [ [ 24, 35 ] ], "normalized": [] }, { "id": "15802", "type": "0", "text": [ "of" ], "offsets": [ [ 27, 29 ] ], "normalized": [] }, { "id": "15803", "type": "0", "text": [ "peptides" ], "offsets": [ [ 36, 44 ] ], "normalized": [] }, { "id": "15804", "type": "0", "text": [ "158-176" ], "offsets": [ [ 44, 51 ] ], "normalized": [] }, { "id": "15805", "type": "0", "text": [ "and" ], "offsets": [ [ 48, 51 ] ], "normalized": [] }, { "id": "15806", "type": "0", "text": [ "248-263" ], "offsets": [ [ 56, 63 ] ], "normalized": [] }, { "id": "15807", "type": "0", "text": [ "is" ], "offsets": [ [ 59, 61 ] ], "normalized": [] }, { "id": "15808", "type": "0", "text": [ "important" ], "offsets": [ [ 69, 78 ] ], "normalized": [] }, { "id": "15809", "type": "0", "text": [ "for" ], "offsets": [ [ 73, 76 ] ], "normalized": [] }, { "id": "15810", "type": "0", "text": [ "the" ], "offsets": [ [ 77, 80 ] ], "normalized": [] }, { "id": "15811", "type": "0", "text": [ "development" ], "offsets": [ [ 89, 100 ] ], "normalized": [] }, { "id": "15812", "type": "0", "text": [ "of" ], "offsets": [ [ 92, 94 ] ], "normalized": [] }, { "id": "15813", "type": "0", "text": [ "GD" ], "offsets": [ [ 95, 97 ] ], "normalized": [] }, { "id": "15814", "type": "0", "text": [ "," ], "offsets": [ [ 97, 98 ] ], "normalized": [] }, { "id": "15815", "type": "0", "text": [ "and" ], "offsets": [ [ 101, 104 ] ], "normalized": [] }, { "id": "15816", "type": "0", "text": [ "the" ], "offsets": [ [ 105, 108 ] ], "normalized": [] }, { "id": "15817", "type": "0", "text": [ "loss" ], "offsets": [ [ 110, 114 ] ], "normalized": [] }, { "id": "15818", "type": "0", "text": [ "of" ], "offsets": [ [ 113, 115 ] ], "normalized": [] }, { "id": "15819", "type": "0", "text": [ "recognition" ], "offsets": [ [ 125, 136 ] ], "normalized": [] }, { "id": "15820", "type": "0", "text": [ "of" ], "offsets": [ [ 128, 130 ] ], "normalized": [] }, { "id": "15821", "type": "0", "text": [ "one" ], "offsets": [ [ 132, 135 ] ], "normalized": [] }, { "id": "15822", "type": "0", "text": [ "of" ], "offsets": [ [ 135, 137 ] ], "normalized": [] }, { "id": "15823", "type": "0", "text": [ "these" ], "offsets": [ [ 141, 146 ] ], "normalized": [] }, { "id": "15824", "type": "9", "text": [ "epitopes" ], "offsets": [ [ 150, 158 ] ], "normalized": [] }, { "id": "15825", "type": "0", "text": [ "may" ], "offsets": [ [ 154, 157 ] ], "normalized": [] }, { "id": "15826", "type": "0", "text": [ "be" ], "offsets": [ [ 157, 159 ] ], "normalized": [] }, { "id": "15827", "type": "0", "text": [ "an" ], "offsets": [ [ 160, 162 ] ], "normalized": [] }, { "id": "15828", "type": "0", "text": [ "early" ], "offsets": [ [ 166, 171 ] ], "normalized": [] }, { "id": "15829", "type": "0", "text": [ "sign" ], "offsets": [ [ 171, 175 ] ], "normalized": [] }, { "id": "15830", "type": "0", "text": [ "of" ], "offsets": [ [ 174, 176 ] ], "normalized": [] }, { "id": "15831", "type": "0", "text": [ "immune" ], "offsets": [ [ 181, 187 ] ], "normalized": [] }, { "id": "15832", "type": "0", "text": [ "remission" ], "offsets": [ [ 191, 200 ] ], "normalized": [] }, { "id": "15833", "type": "0", "text": [ "and" ], "offsets": [ [ 195, 198 ] ], "normalized": [] }, { "id": "15834", "type": "0", "text": [ "a" ], "offsets": [ [ 197, 198 ] ], "normalized": [] }, { "id": "15835", "type": "0", "text": [ "predictor" ], "offsets": [ [ 207, 216 ] ], "normalized": [] }, { "id": "15836", "type": "0", "text": [ "of" ], "offsets": [ [ 210, 212 ] ], "normalized": [] }, { "id": "15837", "type": "0", "text": [ "euthyroidism" ], "offsets": [ [ 223, 235 ] ], "normalized": [] }, { "id": "15838", "type": "0", "text": [ "." ], "offsets": [ [ 225, 226 ] ], "normalized": [] } ]
[]
[]
[]
15839
NULL
[]
[ { "id": "15840", "type": "0", "text": [ "Circumvention" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "15841", "type": "0", "text": [ "of" ], "offsets": [ [ 17, 19 ] ], "normalized": [] }, { "id": "15842", "type": "0", "text": [ "tolerance" ], "offsets": [ [ 27, 36 ] ], "normalized": [] }, { "id": "15843", "type": "0", "text": [ "for" ], "offsets": [ [ 31, 34 ] ], "normalized": [] }, { "id": "15844", "type": "0", "text": [ "the" ], "offsets": [ [ 35, 38 ] ], "normalized": [] }, { "id": "15845", "type": "9", "text": [ "nuclear" ], "offsets": [ [ 43, 50 ] ], "normalized": [] }, { "id": "15846", "type": "10", "text": [ "T" ], "offsets": [ [ 45, 46 ] ], "normalized": [] }, { "id": "15847", "type": "10", "text": [ "cell" ], "offsets": [ [ 50, 54 ] ], "normalized": [] }, { "id": "15848", "type": "10", "text": [ "protein" ], "offsets": [ [ 58, 65 ] ], "normalized": [] }, { "id": "15849", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 64, 69 ] ], "normalized": [] }, { "id": "15850", "type": "0", "text": [ "by" ], "offsets": [ [ 67, 69 ] ], "normalized": [] }, { "id": "15851", "type": "0", "text": [ "immunization" ], "offsets": [ [ 80, 92 ] ], "normalized": [] }, { "id": "15852", "type": "0", "text": [ "of" ], "offsets": [ [ 83, 85 ] ], "normalized": [] }, { "id": "15853", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 89, 94 ] ], "normalized": [] }, { "id": "15854", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 99, 108 ] ], "normalized": [] }, { "id": "15855", "type": "0", "text": [ "mice" ], "offsets": [ [ 104, 108 ] ], "normalized": [] }, { "id": "15856", "type": "0", "text": [ "." ], "offsets": [ [ 106, 107 ] ], "normalized": [] } ]
[]
[]
[]
15857
NULL
[]
[ { "id": "15858", "type": "0", "text": [ "Molecular" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "15859", "type": "0", "text": [ "events" ], "offsets": [ [ 17, 23 ] ], "normalized": [] }, { "id": "15860", "type": "0", "text": [ "that" ], "offsets": [ [ 22, 26 ] ], "normalized": [] }, { "id": "15861", "type": "0", "text": [ "underlie" ], "offsets": [ [ 31, 39 ] ], "normalized": [] }, { "id": "15862", "type": "0", "text": [ "the" ], "offsets": [ [ 35, 38 ] ], "normalized": [] }, { "id": "15863", "type": "0", "text": [ "well-defined" ], "offsets": [ [ 48, 60 ] ], "normalized": [] }, { "id": "15864", "type": "0", "text": [ "phenotypic" ], "offsets": [ [ 59, 69 ] ], "normalized": [] }, { "id": "15865", "type": "0", "text": [ "changes" ], "offsets": [ [ 67, 74 ] ], "normalized": [] }, { "id": "15866", "type": "0", "text": [ "of" ], "offsets": [ [ 70, 72 ] ], "normalized": [] }, { "id": "15867", "type": "0", "text": [ "the" ], "offsets": [ [ 74, 77 ] ], "normalized": [] }, { "id": "15868", "type": "7", "text": [ "differentiating" ], "offsets": [ [ 90, 105 ] ], "normalized": [] }, { "id": "15869", "type": "8", "text": [ "thymocyte" ], "offsets": [ [ 100, 109 ] ], "normalized": [] }, { "id": "15870", "type": "0", "text": [ "are" ], "offsets": [ [ 104, 107 ] ], "normalized": [] }, { "id": "15871", "type": "0", "text": [ "poorly" ], "offsets": [ [ 111, 117 ] ], "normalized": [] }, { "id": "15872", "type": "0", "text": [ "understood" ], "offsets": [ [ 122, 132 ] ], "normalized": [] }, { "id": "15873", "type": "0", "text": [ "." ], "offsets": [ [ 124, 125 ] ], "normalized": [] } ]
[]
[]
[]
15874
NULL
[]
[ { "id": "15875", "type": "0", "text": [ "A" ], "offsets": [ [ 2, 3 ] ], "normalized": [] }, { "id": "15876", "type": "0", "text": [ "candidate" ], "offsets": [ [ 12, 21 ] ], "normalized": [] }, { "id": "15877", "type": "0", "text": [ "gene" ], "offsets": [ [ 17, 21 ] ], "normalized": [] }, { "id": "15878", "type": "0", "text": [ "to" ], "offsets": [ [ 20, 22 ] ], "normalized": [] }, { "id": "15879", "type": "0", "text": [ "control" ], "offsets": [ [ 28, 35 ] ], "normalized": [] }, { "id": "15880", "type": "7", "text": [ "thymocyte" ], "offsets": [ [ 38, 47 ] ], "normalized": [] }, { "id": "15881", "type": "0", "text": [ "differentiation" ], "offsets": [ [ 54, 69 ] ], "normalized": [] }, { "id": "15882", "type": "0", "text": [ "," ], "offsets": [ [ 56, 57 ] ], "normalized": [] }, { "id": "15883", "type": "9", "text": [ "T" ], "offsets": [ [ 58, 59 ] ], "normalized": [] }, { "id": "15884", "type": "10", "text": [ "cell" ], "offsets": [ [ 63, 67 ] ], "normalized": [] }, { "id": "15885", "type": "10", "text": [ "factor-1" ], "offsets": [ [ 72, 80 ] ], "normalized": [] }, { "id": "15886", "type": "0", "text": [ "(" ], "offsets": [ [ 74, 75 ] ], "normalized": [] }, { "id": "15887", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 80, 85 ] ], "normalized": [] }, { "id": "15888", "type": "0", "text": [ ")" ], "offsets": [ [ 82, 83 ] ], "normalized": [] }, { "id": "15889", "type": "0", "text": [ "*" ], "offsets": [ [ 84, 85 ] ], "normalized": [] }, { "id": "15890", "type": "0", "text": [ "encodes" ], "offsets": [ [ 92, 99 ] ], "normalized": [] }, { "id": "15891", "type": "0", "text": [ "a" ], "offsets": [ [ 94, 95 ] ], "normalized": [] }, { "id": "15892", "type": "9", "text": [ "DNA-binding" ], "offsets": [ [ 106, 117 ] ], "normalized": [] }, { "id": "15893", "type": "10", "text": [ "protein" ], "offsets": [ [ 114, 121 ] ], "normalized": [] }, { "id": "15894", "type": "0", "text": [ "." ], "offsets": [ [ 116, 117 ] ], "normalized": [] } ]
[]
[]
[]
15895
NULL
[]
[ { "id": "15896", "type": "0", "text": [ "Its" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "15897", "type": "0", "text": [ "mRNA" ], "offsets": [ [ 9, 13 ] ], "normalized": [] }, { "id": "15898", "type": "0", "text": [ "expression" ], "offsets": [ [ 20, 30 ] ], "normalized": [] }, { "id": "15899", "type": "0", "text": [ "pattern" ], "offsets": [ [ 28, 35 ] ], "normalized": [] }, { "id": "15900", "type": "0", "text": [ "is" ], "offsets": [ [ 31, 33 ] ], "normalized": [] }, { "id": "15901", "type": "0", "text": [ "complex" ], "offsets": [ [ 39, 46 ] ], "normalized": [] }, { "id": "15902", "type": "0", "text": [ "during" ], "offsets": [ [ 46, 52 ] ], "normalized": [] }, { "id": "15903", "type": "0", "text": [ "embryogenesis" ], "offsets": [ [ 60, 73 ] ], "normalized": [] }, { "id": "15904", "type": "0", "text": [ "," ], "offsets": [ [ 62, 63 ] ], "normalized": [] }, { "id": "15905", "type": "0", "text": [ "yet" ], "offsets": [ [ 66, 69 ] ], "normalized": [] }, { "id": "15906", "type": "0", "text": [ "restricted" ], "offsets": [ [ 77, 87 ] ], "normalized": [] }, { "id": "15907", "type": "0", "text": [ "to" ], "offsets": [ [ 80, 82 ] ], "normalized": [] }, { "id": "15908", "type": "7", "text": [ "lymphocytes" ], "offsets": [ [ 92, 103 ] ], "normalized": [] }, { "id": "15909", "type": "0", "text": [ "postnatally" ], "offsets": [ [ 104, 115 ] ], "normalized": [] }, { "id": "15910", "type": "0", "text": [ "." ], "offsets": [ [ 106, 107 ] ], "normalized": [] } ]
[]
[]
[]
15911
NULL
[]
[ { "id": "15912", "type": "0", "text": [ "Expression" ], "offsets": [ [ 11, 21 ] ], "normalized": [] }, { "id": "15913", "type": "0", "text": [ "studies" ], "offsets": [ [ 19, 26 ] ], "normalized": [] }, { "id": "15914", "type": "0", "text": [ "on" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "15915", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 28, 33 ] ], "normalized": [] }, { "id": "15916", "type": "10", "text": [ "protein" ], "offsets": [ [ 36, 43 ] ], "normalized": [] }, { "id": "15917", "type": "0", "text": [ "have" ], "offsets": [ [ 41, 45 ] ], "normalized": [] }, { "id": "15918", "type": "0", "text": [ "been" ], "offsets": [ [ 46, 50 ] ], "normalized": [] }, { "id": "15919", "type": "0", "text": [ "hampered" ], "offsets": [ [ 55, 63 ] ], "normalized": [] }, { "id": "15920", "type": "0", "text": [ "by" ], "offsets": [ [ 58, 60 ] ], "normalized": [] }, { "id": "15921", "type": "0", "text": [ "the" ], "offsets": [ [ 62, 65 ] ], "normalized": [] }, { "id": "15922", "type": "0", "text": [ "difficulty" ], "offsets": [ [ 73, 83 ] ], "normalized": [] }, { "id": "15923", "type": "0", "text": [ "to" ], "offsets": [ [ 76, 78 ] ], "normalized": [] }, { "id": "15924", "type": "0", "text": [ "raise" ], "offsets": [ [ 82, 87 ] ], "normalized": [] }, { "id": "15925", "type": "9", "text": [ "antibodies" ], "offsets": [ [ 93, 103 ] ], "normalized": [] }, { "id": "15926", "type": "0", "text": [ "due" ], "offsets": [ [ 97, 100 ] ], "normalized": [] }, { "id": "15927", "type": "0", "text": [ "to" ], "offsets": [ [ 100, 102 ] ], "normalized": [] }, { "id": "15928", "type": "0", "text": [ "extreme" ], "offsets": [ [ 108, 115 ] ], "normalized": [] }, { "id": "15929", "type": "0", "text": [ "evolutionary" ], "offsets": [ [ 121, 133 ] ], "normalized": [] }, { "id": "15930", "type": "0", "text": [ "conservation" ], "offsets": [ [ 134, 146 ] ], "normalized": [] }, { "id": "15931", "type": "0", "text": [ "." ], "offsets": [ [ 136, 137 ] ], "normalized": [] } ]
[]
[]
[]
15932
NULL
[]
[ { "id": "15933", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "15934", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 16, 25 ] ], "normalized": [] }, { "id": "15935", "type": "0", "text": [ "mice" ], "offsets": [ [ 21, 25 ] ], "normalized": [] }, { "id": "15936", "type": "0", "text": [ "," ], "offsets": [ [ 23, 24 ] ], "normalized": [] }, { "id": "15937", "type": "0", "text": [ "generated" ], "offsets": [ [ 33, 42 ] ], "normalized": [] }, { "id": "15938", "type": "0", "text": [ "recently" ], "offsets": [ [ 42, 50 ] ], "normalized": [] }, { "id": "15939", "type": "0", "text": [ "in" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "15940", "type": "0", "text": [ "our" ], "offsets": [ [ 49, 52 ] ], "normalized": [] }, { "id": "15941", "type": "0", "text": [ "laboratory" ], "offsets": [ [ 60, 70 ] ], "normalized": [] }, { "id": "15942", "type": "0", "text": [ "," ], "offsets": [ [ 62, 63 ] ], "normalized": [] }, { "id": "15943", "type": "0", "text": [ "have" ], "offsets": [ [ 67, 71 ] ], "normalized": [] }, { "id": "15944", "type": "0", "text": [ "strongly" ], "offsets": [ [ 76, 84 ] ], "normalized": [] }, { "id": "15945", "type": "0", "text": [ "decreased" ], "offsets": [ [ 86, 95 ] ], "normalized": [] }, { "id": "15946", "type": "0", "text": [ "numbers" ], "offsets": [ [ 94, 101 ] ], "normalized": [] }, { "id": "15947", "type": "0", "text": [ "of" ], "offsets": [ [ 97, 99 ] ], "normalized": [] }, { "id": "15948", "type": "7", "text": [ "thymocytes" ], "offsets": [ [ 108, 118 ] ], "normalized": [] }, { "id": "15949", "type": "0", "text": [ "," ], "offsets": [ [ 110, 111 ] ], "normalized": [] }, { "id": "15950", "type": "0", "text": [ "but" ], "offsets": [ [ 114, 117 ] ], "normalized": [] }, { "id": "15951", "type": "0", "text": [ "are" ], "offsets": [ [ 118, 121 ] ], "normalized": [] }, { "id": "15952", "type": "0", "text": [ "otherwise" ], "offsets": [ [ 128, 137 ] ], "normalized": [] }, { "id": "15953", "type": "0", "text": [ "normal" ], "offsets": [ [ 135, 141 ] ], "normalized": [] }, { "id": "15954", "type": "0", "text": [ "." ], "offsets": [ [ 137, 138 ] ], "normalized": [] } ]
[]
[]
[]
15955
NULL
[]
[ { "id": "15956", "type": "0", "text": [ "We" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "15957", "type": "0", "text": [ "have" ], "offsets": [ [ 8, 12 ] ], "normalized": [] }, { "id": "15958", "type": "0", "text": [ "used" ], "offsets": [ [ 13, 17 ] ], "normalized": [] }, { "id": "15959", "type": "0", "text": [ "these" ], "offsets": [ [ 19, 24 ] ], "normalized": [] }, { "id": "15960", "type": "0", "text": [ "mice" ], "offsets": [ [ 24, 28 ] ], "normalized": [] }, { "id": "15961", "type": "0", "text": [ "to" ], "offsets": [ [ 27, 29 ] ], "normalized": [] }, { "id": "15962", "type": "0", "text": [ "generate" ], "offsets": [ [ 36, 44 ] ], "normalized": [] }, { "id": "15963", "type": "9", "text": [ "anti-TCF-1" ], "offsets": [ [ 47, 57 ] ], "normalized": [] }, { "id": "15964", "type": "10", "text": [ "antibodies" ], "offsets": [ [ 58, 68 ] ], "normalized": [] }, { "id": "15965", "type": "0", "text": [ "." ], "offsets": [ [ 60, 61 ] ], "normalized": [] } ]
[]
[]
[]
15966
NULL
[]
[ { "id": "15967", "type": "0", "text": [ "By" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "15968", "type": "0", "text": [ "immunization" ], "offsets": [ [ 16, 28 ] ], "normalized": [] }, { "id": "15969", "type": "0", "text": [ "with" ], "offsets": [ [ 21, 25 ] ], "normalized": [] }, { "id": "15970", "type": "0", "text": [ "a" ], "offsets": [ [ 23, 24 ] ], "normalized": [] }, { "id": "15971", "type": "9", "text": [ "recombinant" ], "offsets": [ [ 35, 46 ] ], "normalized": [] }, { "id": "15972", "type": "10", "text": [ "fusion" ], "offsets": [ [ 42, 48 ] ], "normalized": [] }, { "id": "15973", "type": "10", "text": [ "protein" ], "offsets": [ [ 50, 57 ] ], "normalized": [] }, { "id": "15974", "type": "0", "text": [ "," ], "offsets": [ [ 52, 53 ] ], "normalized": [] }, { "id": "15975", "type": "0", "text": [ "we" ], "offsets": [ [ 55, 57 ] ], "normalized": [] }, { "id": "15976", "type": "0", "text": [ "show" ], "offsets": [ [ 60, 64 ] ], "normalized": [] }, { "id": "15977", "type": "0", "text": [ "that" ], "offsets": [ [ 65, 69 ] ], "normalized": [] }, { "id": "15978", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 71, 76 ] ], "normalized": [] }, { "id": "15979", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 81, 90 ] ], "normalized": [] }, { "id": "15980", "type": "0", "text": [ "mice" ], "offsets": [ [ 86, 90 ] ], "normalized": [] }, { "id": "15981", "type": "0", "text": [ "readily" ], "offsets": [ [ 94, 101 ] ], "normalized": [] }, { "id": "15982", "type": "0", "text": [ "yield" ], "offsets": [ [ 100, 105 ] ], "normalized": [] }, { "id": "15983", "type": "0", "text": [ "antiserum" ], "offsets": [ [ 110, 119 ] ], "normalized": [] }, { "id": "15984", "type": "0", "text": [ "titers" ], "offsets": [ [ 117, 123 ] ], "normalized": [] }, { "id": "15985", "type": "0", "text": [ "against" ], "offsets": [ [ 125, 132 ] ], "normalized": [] }, { "id": "15986", "type": "0", "text": [ "human" ], "offsets": [ [ 131, 136 ] ], "normalized": [] }, { "id": "15987", "type": "0", "text": [ "and" ], "offsets": [ [ 135, 138 ] ], "normalized": [] }, { "id": "15988", "type": "0", "text": [ "mouse" ], "offsets": [ [ 141, 146 ] ], "normalized": [] }, { "id": "15989", "type": "0", "text": [ "TCF-1" ], "offsets": [ [ 147, 152 ] ], "normalized": [] }, { "id": "15990", "type": "0", "text": [ "protein" ], "offsets": [ [ 155, 162 ] ], "normalized": [] }, { "id": "15991", "type": "0", "text": [ "." ], "offsets": [ [ 157, 158 ] ], "normalized": [] } ]
[]
[]
[]
15992
NULL
[]
[ { "id": "15993", "type": "0", "text": [ "Wild-type" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "15994", "type": "0", "text": [ "littermates" ], "offsets": [ [ 22, 33 ] ], "normalized": [] }, { "id": "15995", "type": "0", "text": [ "remain" ], "offsets": [ [ 29, 35 ] ], "normalized": [] }, { "id": "15996", "type": "0", "text": [ "unresponsive" ], "offsets": [ [ 42, 54 ] ], "normalized": [] }, { "id": "15997", "type": "0", "text": [ "to" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "15998", "type": "9", "text": [ "TCF-1" ], "offsets": [ [ 51, 56 ] ], "normalized": [] }, { "id": "15999", "type": "0", "text": [ "while" ], "offsets": [ [ 57, 62 ] ], "normalized": [] }, { "id": "16000", "type": "0", "text": [ "they" ], "offsets": [ [ 62, 66 ] ], "normalized": [] }, { "id": "16001", "type": "0", "text": [ "mount" ], "offsets": [ [ 68, 73 ] ], "normalized": [] }, { "id": "16002", "type": "0", "text": [ "a" ], "offsets": [ [ 70, 71 ] ], "normalized": [] }, { "id": "16003", "type": "0", "text": [ "high-titer" ], "offsets": [ [ 81, 91 ] ], "normalized": [] }, { "id": "16004", "type": "0", "text": [ "antibody" ], "offsets": [ [ 90, 98 ] ], "normalized": [] }, { "id": "16005", "type": "0", "text": [ "response" ], "offsets": [ [ 99, 107 ] ], "normalized": [] }, { "id": "16006", "type": "0", "text": [ "to" ], "offsets": [ [ 102, 104 ] ], "normalized": [] }, { "id": "16007", "type": "0", "text": [ "the" ], "offsets": [ [ 106, 109 ] ], "normalized": [] }, { "id": "16008", "type": "9", "text": [ "fusion" ], "offsets": [ [ 113, 119 ] ], "normalized": [] }, { "id": "16009", "type": "10", "text": [ "protein" ], "offsets": [ [ 121, 128 ] ], "normalized": [] }, { "id": "16010", "type": "0", "text": [ "," ], "offsets": [ [ 123, 124 ] ], "normalized": [] }, { "id": "16011", "type": "9", "text": [ "Maltose" ], "offsets": [ [ 131, 138 ] ], "normalized": [] }, { "id": "16012", "type": "10", "text": [ "Binding" ], "offsets": [ [ 139, 146 ] ], "normalized": [] }, { "id": "16013", "type": "10", "text": [ "Protein" ], "offsets": [ [ 147, 154 ] ], "normalized": [] }, { "id": "16014", "type": "0", "text": [ "(" ], "offsets": [ [ 149, 150 ] ], "normalized": [] }, { "id": "16015", "type": "9", "text": [ "MBP" ], "offsets": [ [ 153, 156 ] ], "normalized": [] }, { "id": "16016", "type": "0", "text": [ ")" ], "offsets": [ [ 155, 156 ] ], "normalized": [] }, { "id": "16017", "type": "0", "text": [ "." ], "offsets": [ [ 157, 158 ] ], "normalized": [] } ]
[]
[]
[]
16018
NULL
[]
[ { "id": "16019", "type": "0", "text": [ "Subsequently" ], "offsets": [ [ 13, 25 ] ], "normalized": [] }, { "id": "16020", "type": "0", "text": [ "," ], "offsets": [ [ 15, 16 ] ], "normalized": [] }, { "id": "16021", "type": "5", "text": [ "TCF-1-specific" ], "offsets": [ [ 30, 44 ] ], "normalized": [] }, { "id": "16022", "type": "6", "text": [ "hybridomas" ], "offsets": [ [ 41, 51 ] ], "normalized": [] }, { "id": "16023", "type": "0", "text": [ "could" ], "offsets": [ [ 47, 52 ] ], "normalized": [] }, { "id": "16024", "type": "0", "text": [ "be" ], "offsets": [ [ 50, 52 ] ], "normalized": [] }, { "id": "16025", "type": "0", "text": [ "prepared" ], "offsets": [ [ 59, 67 ] ], "normalized": [] }, { "id": "16026", "type": "0", "text": [ "from" ], "offsets": [ [ 64, 68 ] ], "normalized": [] }, { "id": "16027", "type": "0", "text": [ "the" ], "offsets": [ [ 68, 71 ] ], "normalized": [] }, { "id": "16028", "type": "0", "text": [ "spleens" ], "offsets": [ [ 76, 83 ] ], "normalized": [] }, { "id": "16029", "type": "0", "text": [ "of" ], "offsets": [ [ 79, 81 ] ], "normalized": [] }, { "id": "16030", "type": "0", "text": [ "immunized" ], "offsets": [ [ 89, 98 ] ], "normalized": [] }, { "id": "16031", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 99, 108 ] ], "normalized": [] }, { "id": "16032", "type": "0", "text": [ "mice" ], "offsets": [ [ 104, 108 ] ], "normalized": [] }, { "id": "16033", "type": "0", "text": [ "." ], "offsets": [ [ 106, 107 ] ], "normalized": [] } ]
[]
[]
[]
16034
NULL
[]
[ { "id": "16035", "type": "0", "text": [ "This" ], "offsets": [ [ 5, 9 ] ], "normalized": [] }, { "id": "16036", "type": "0", "text": [ "study" ], "offsets": [ [ 11, 16 ] ], "normalized": [] }, { "id": "16037", "type": "0", "text": [ "illustrates" ], "offsets": [ [ 23, 34 ] ], "normalized": [] }, { "id": "16038", "type": "0", "text": [ "the" ], "offsets": [ [ 27, 30 ] ], "normalized": [] }, { "id": "16039", "type": "0", "text": [ "almost" ], "offsets": [ [ 34, 40 ] ], "normalized": [] }, { "id": "16040", "type": "0", "text": [ "complete" ], "offsets": [ [ 43, 51 ] ], "normalized": [] }, { "id": "16041", "type": "0", "text": [ "tolerance" ], "offsets": [ [ 53, 62 ] ], "normalized": [] }, { "id": "16042", "type": "0", "text": [ "of" ], "offsets": [ [ 56, 58 ] ], "normalized": [] }, { "id": "16043", "type": "0", "text": [ "mice" ], "offsets": [ [ 61, 65 ] ], "normalized": [] }, { "id": "16044", "type": "0", "text": [ "for" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "16045", "type": "9", "text": [ "human" ], "offsets": [ [ 71, 76 ] ], "normalized": [] }, { "id": "16046", "type": "10", "text": [ "TCF-1" ], "offsets": [ [ 77, 82 ] ], "normalized": [] }, { "id": "16047", "type": "0", "text": [ "and" ], "offsets": [ [ 81, 84 ] ], "normalized": [] }, { "id": "16048", "type": "0", "text": [ "demonstrates" ], "offsets": [ [ 94, 106 ] ], "normalized": [] }, { "id": "16049", "type": "0", "text": [ "that" ], "offsets": [ [ 99, 103 ] ], "normalized": [] }, { "id": "16050", "type": "0", "text": [ "this" ], "offsets": [ [ 104, 108 ] ], "normalized": [] }, { "id": "16051", "type": "0", "text": [ "tolerance" ], "offsets": [ [ 114, 123 ] ], "normalized": [] }, { "id": "16052", "type": "0", "text": [ "is" ], "offsets": [ [ 117, 119 ] ], "normalized": [] }, { "id": "16053", "type": "0", "text": [ "readily" ], "offsets": [ [ 125, 132 ] ], "normalized": [] }, { "id": "16054", "type": "0", "text": [ "broken" ], "offsets": [ [ 132, 138 ] ], "normalized": [] }, { "id": "16055", "type": "0", "text": [ "by" ], "offsets": [ [ 135, 137 ] ], "normalized": [] }, { "id": "16056", "type": "0", "text": [ "gene" ], "offsets": [ [ 140, 144 ] ], "normalized": [] }, { "id": "16057", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 150, 159 ] ], "normalized": [] }, { "id": "16058", "type": "0", "text": [ "." ], "offsets": [ [ 152, 153 ] ], "normalized": [] } ]
[]
[]
[]
16059
NULL
[]
[ { "id": "16060", "type": "0", "text": [ "Furthermore" ], "offsets": [ [ 12, 23 ] ], "normalized": [] }, { "id": "16061", "type": "0", "text": [ "," ], "offsets": [ [ 14, 15 ] ], "normalized": [] }, { "id": "16062", "type": "0", "text": [ "the" ], "offsets": [ [ 18, 21 ] ], "normalized": [] }, { "id": "16063", "type": "0", "text": [ "usefulness" ], "offsets": [ [ 29, 39 ] ], "normalized": [] }, { "id": "16064", "type": "0", "text": [ "of" ], "offsets": [ [ 32, 34 ] ], "normalized": [] }, { "id": "16065", "type": "0", "text": [ "knock-out" ], "offsets": [ [ 42, 51 ] ], "normalized": [] }, { "id": "16066", "type": "0", "text": [ "mice" ], "offsets": [ [ 47, 51 ] ], "normalized": [] }, { "id": "16067", "type": "0", "text": [ "for" ], "offsets": [ [ 51, 54 ] ], "normalized": [] }, { "id": "16068", "type": "0", "text": [ "the" ], "offsets": [ [ 55, 58 ] ], "normalized": [] }, { "id": "16069", "type": "0", "text": [ "generation" ], "offsets": [ [ 66, 76 ] ], "normalized": [] }, { "id": "16070", "type": "0", "text": [ "of" ], "offsets": [ [ 69, 71 ] ], "normalized": [] }, { "id": "16071", "type": "9", "text": [ "monoclonal" ], "offsets": [ [ 80, 90 ] ], "normalized": [] }, { "id": "16072", "type": "10", "text": [ "antibodies" ], "offsets": [ [ 91, 101 ] ], "normalized": [] }, { "id": "16073", "type": "0", "text": [ "against" ], "offsets": [ [ 99, 106 ] ], "normalized": [] }, { "id": "16074", "type": "0", "text": [ "the" ], "offsets": [ [ 103, 106 ] ], "normalized": [] }, { "id": "16075", "type": "0", "text": [ "gene" ], "offsets": [ [ 108, 112 ] ], "normalized": [] }, { "id": "16076", "type": "0", "text": [ "product" ], "offsets": [ [ 116, 123 ] ], "normalized": [] }, { "id": "16077", "type": "0", "text": [ "of" ], "offsets": [ [ 119, 121 ] ], "normalized": [] }, { "id": "16078", "type": "0", "text": [ "interest" ], "offsets": [ [ 128, 136 ] ], "normalized": [] }, { "id": "16079", "type": "0", "text": [ "is" ], "offsets": [ [ 131, 133 ] ], "normalized": [] }, { "id": "16080", "type": "0", "text": [ "underscored" ], "offsets": [ [ 143, 154 ] ], "normalized": [] }, { "id": "16081", "type": "0", "text": [ "." ], "offsets": [ [ 145, 146 ] ], "normalized": [] } ]
[]
[]
[]
16082
NULL
[]
[ { "id": "16083", "type": "0", "text": [ "The" ], "offsets": [ [ 4, 7 ] ], "normalized": [] }, { "id": "16084", "type": "9", "text": [ "transcription" ], "offsets": [ [ 18, 31 ] ], "normalized": [] }, { "id": "16085", "type": "10", "text": [ "factor" ], "offsets": [ [ 25, 31 ] ], "normalized": [] }, { "id": "16086", "type": "0", "text": [ "," ], "offsets": [ [ 27, 28 ] ], "normalized": [] }, { "id": "16087", "type": "9", "text": [ "Nm23H2" ], "offsets": [ [ 34, 40 ] ], "normalized": [] }, { "id": "16088", "type": "0", "text": [ "," ], "offsets": [ [ 36, 37 ] ], "normalized": [] }, { "id": "16089", "type": "0", "text": [ "binds" ], "offsets": [ [ 42, 47 ] ], "normalized": [] }, { "id": "16090", "type": "0", "text": [ "to" ], "offsets": [ [ 45, 47 ] ], "normalized": [] }, { "id": "16091", "type": "0", "text": [ "and" ], "offsets": [ [ 49, 52 ] ], "normalized": [] }, { "id": "16092", "type": "0", "text": [ "activates" ], "offsets": [ [ 59, 68 ] ], "normalized": [] }, { "id": "16093", "type": "0", "text": [ "the" ], "offsets": [ [ 63, 66 ] ], "normalized": [] }, { "id": "16094", "type": "0", "text": [ "translocated" ], "offsets": [ [ 76, 88 ] ], "normalized": [] }, { "id": "16095", "type": "1", "text": [ "c-myc" ], "offsets": [ [ 82, 87 ] ], "normalized": [] }, { "id": "16096", "type": "2", "text": [ "allele" ], "offsets": [ [ 89, 95 ] ], "normalized": [] }, { "id": "16097", "type": "0", "text": [ "in" ], "offsets": [ [ 92, 94 ] ], "normalized": [] }, { "id": "16098", "type": "0", "text": [ "Burkitt" ], "offsets": [ [ 100, 107 ] ], "normalized": [] }, { "id": "16099", "type": "0", "text": [ "'s" ], "offsets": [ [ 103, 105 ] ], "normalized": [] }, { "id": "16100", "type": "0", "text": [ "lymphoma" ], "offsets": [ [ 112, 120 ] ], "normalized": [] }, { "id": "16101", "type": "0", "text": [ "." ], "offsets": [ [ 114, 115 ] ], "normalized": [] } ]
[]
[]
[]
16102
NULL
[]
[ { "id": "16103", "type": "0", "text": [ "We" ], "offsets": [ [ 3, 5 ] ], "normalized": [] }, { "id": "16104", "type": "0", "text": [ "have" ], "offsets": [ [ 8, 12 ] ], "normalized": [] }, { "id": "16105", "type": "0", "text": [ "identified" ], "offsets": [ [ 19, 29 ] ], "normalized": [] }, { "id": "16106", "type": "0", "text": [ "an" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "16107", "type": "0", "text": [ "in" ], "offsets": [ [ 25, 27 ] ], "normalized": [] }, { "id": "16108", "type": "0", "text": [ "vivo" ], "offsets": [ [ 30, 34 ] ], "normalized": [] }, { "id": "16109", "type": "0", "text": [ "footprint" ], "offsets": [ [ 40, 49 ] ], "normalized": [] }, { "id": "16110", "type": "0", "text": [ "over" ], "offsets": [ [ 45, 49 ] ], "normalized": [] }, { "id": "16111", "type": "0", "text": [ "the" ], "offsets": [ [ 49, 52 ] ], "normalized": [] }, { "id": "16112", "type": "1", "text": [ "PuF" ], "offsets": [ [ 53, 56 ] ], "normalized": [] }, { "id": "16113", "type": "2", "text": [ "site" ], "offsets": [ [ 58, 62 ] ], "normalized": [] }, { "id": "16114", "type": "0", "text": [ "on" ], "offsets": [ [ 61, 63 ] ], "normalized": [] }, { "id": "16115", "type": "0", "text": [ "the" ], "offsets": [ [ 65, 68 ] ], "normalized": [] }, { "id": "16116", "type": "0", "text": [ "translocated" ], "offsets": [ [ 78, 90 ] ], "normalized": [] }, { "id": "16117", "type": "1", "text": [ "c-myc" ], "offsets": [ [ 84, 89 ] ], "normalized": [] }, { "id": "16118", "type": "2", "text": [ "allele" ], "offsets": [ [ 91, 97 ] ], "normalized": [] }, { "id": "16119", "type": "0", "text": [ "in" ], "offsets": [ [ 94, 96 ] ], "normalized": [] }, { "id": "16120", "type": "0", "text": [ "Burkitt" ], "offsets": [ [ 102, 109 ] ], "normalized": [] }, { "id": "16121", "type": "0", "text": [ "'s" ], "offsets": [ [ 105, 107 ] ], "normalized": [] }, { "id": "16122", "type": "0", "text": [ "lymphoma" ], "offsets": [ [ 114, 122 ] ], "normalized": [] }, { "id": "16123", "type": "0", "text": [ "cells" ], "offsets": [ [ 120, 125 ] ], "normalized": [] }, { "id": "16124", "type": "0", "text": [ "." ], "offsets": [ [ 122, 123 ] ], "normalized": [] } ]
[]
[]
[]