id
int32 0
1.41k
| claim
stringlengths 26
249
| evidences
list | cited_doc_ids
list |
|---|---|---|---|
1,219 | The gene daf-16, which encodes forkhead Box O (FOXO), is required for all phenotypes associated with reduced insulin/insulin-like growth factor (Igf) signaling. | [] | [
9393969,
14864285
] |
1,220 | The generation of reactive oxygen species by activated oncogenes contributes to the increased genomic instability of leukaemia cells. | [
{
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"sentence_ids": [
0,
1
],
"label": "SUPPORT"
},
{
"doc_id": 13023410,
"sentence_ids": [
5
],
"label": "SUPPORT"
}
] | [
13023410
] |
1,223 | The innate immune response struggles to remove small numbers of parasites. | [
{
"doc_id": 5289038,
"sentence_ids": [
3
],
"label": "CONTRADICT"
}
] | [
5289038
] |
1,224 | The latent infection of myeloid cells with human cytomegalovirus induces a number of changes in gene expression. | [
{
"doc_id": 21932050,
"sentence_ids": [
3
],
"label": "SUPPORT"
},
{
"doc_id": 34016987,
"sentence_ids": [
4
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"label": "SUPPORT"
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{
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5
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"label": "SUPPORT"
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{
"doc_id": 34016987,
"sentence_ids": [
9
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"label": "SUPPORT"
}
] | [
21932050,
34016987
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1,227 | The mean suicide rate in women is higher after miscarriage than live birth. | [
{
"doc_id": 25641414,
"sentence_ids": [
7
],
"label": "SUPPORT"
}
] | [
25641414
] |
1,228 | The mean suicide rate in women is lower after miscarriage than live birth. | [
{
"doc_id": 25641414,
"sentence_ids": [
7
],
"label": "CONTRADICT"
}
] | [
25641414
] |
1,229 | The microtubule-dependent delivery and secretion of matrix metalloproteases (MMPs) is partially responsible for the disassembly of adhesion sites. | [
{
"doc_id": 1676568,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
1676568
] |
1,230 | The minor G allele of FOXO3 downregulates pro-inflammatory cytokines. | [
{
"doc_id": 13905670,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
13905670
] |
1,231 | The minor G allele of FOXO3 is related to less severe symptoms of Crohn's Disease. | [
{
"doc_id": 13905670,
"sentence_ids": [
3
],
"label": "SUPPORT"
}
] | [
13905670
] |
1,234 | The minor G allele of FOXO3 up-regulates IL-10. | [
{
"doc_id": 13905670,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
13905670
] |
1,235 | The morphology change from large white adipocytes to small brown adipocytes is a sign of decreased energy expenditure potential in white adipose tissue. | [] | [
17973161
] |
1,236 | The morphology change from large white adipocytes to small brown adipocytes is a sign of increased energy expenditure potential in white adipose tissue. | [] | [
17973161
] |
1,237 | The most prevalent adverse events to Semaglutide are cardiovascular. | [
{
"doc_id": 3654468,
"sentence_ids": [
12
],
"label": "CONTRADICT"
}
] | [
3654468
] |
1,238 | The most prevalent adverse events to Semaglutide are gastrointestinal. | [
{
"doc_id": 3654468,
"sentence_ids": [
12
],
"label": "SUPPORT"
}
] | [
3654468
] |
1,239 | The myocardial cell lineage originally develops from cardiac progenitors of exclusively endodermal origin. | [
{
"doc_id": 4427392,
"sentence_ids": [
1
],
"label": "CONTRADICT"
}
] | [
21387297,
4427392
] |
1,244 | The number of unfertilized oocytes in mated hermaphrodites increases with age. | [] | [
18949516
] |
1,246 | The one-child policy has created a hospitable environment for female infants. | [
{
"doc_id": 7662395,
"sentence_ids": [
10
],
"label": "CONTRADICT"
}
] | [
7662395
] |
1,247 | The origin of the CRF01_1b2k protein occurred between 1923 and 1956. | [] | [
5114282
] |
1,248 | The peak incidence of fractures occurs during pubertal growth spurt in early adolescents. | [
{
"doc_id": 7209559,
"sentence_ids": [
0
],
"label": "SUPPORT"
}
] | [
7209559
] |
1,249 | The peak incidence of fractures occurs in toddlers. | [
{
"doc_id": 7209559,
"sentence_ids": [
0
],
"label": "CONTRADICT"
}
] | [
7209559
] |
1,253 | The predominant localization of Linc00173 is in mononuclear macrophage nuclei. | [] | [
3321943
] |
1,254 | The proliferative capacity of neural progenitors differs across species. | [
{
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"sentence_ids": [
2
],
"label": "SUPPORT"
},
{
"doc_id": 16939583,
"sentence_ids": [
3
],
"label": "SUPPORT"
}
] | [
16939583
] |
1,255 | The proliferative capacity of progenitors is regulated cell-autonomously. | [
{
"doc_id": 16939583,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
16939583
] |
1,257 | The proportion of people with visual difficulty is two times higher in low-income countries than in high-income countries. | [] | [
581832
] |
1,258 | The recruitment of Wdr5 to its target loci depends on Kat8. | [
{
"doc_id": 12040627,
"sentence_ids": [
7
],
"label": "SUPPORT"
}
] | [
12040627
] |
1,260 | The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is independent of the patient's genetic make-up. | [
{
"doc_id": 24341590,
"sentence_ids": [
11
],
"label": "CONTRADICT"
},
{
"doc_id": 24341590,
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12
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"label": "CONTRADICT"
},
{
"doc_id": 24341590,
"sentence_ids": [
13
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] | [
24341590
] |
1,261 | The removal of reactive oxygen species by activated oncogenes contributes to the increased genomic instability of leukaemia cells. | [
{
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"sentence_ids": [
0,
1
],
"label": "CONTRADICT"
},
{
"doc_id": 13023410,
"sentence_ids": [
5
],
"label": "CONTRADICT"
}
] | [
13023410
] |
1,263 | The repeat-variable diresidue (RVD) in the loop of Transcription-Activator Like (TAL) effectors specifies the nucleotides-amino acid contact at the target promoter element. | [
{
"doc_id": 3981729,
"sentence_ids": [
0,
1
],
"label": "SUPPORT"
}
] | [
3981729
] |
1,265 | The risk of breast cancer among parous women decreases with placental weight of pregnancies. | [
{
"doc_id": 37480103,
"sentence_ids": [
10
],
"label": "CONTRADICT"
},
{
"doc_id": 37480103,
"sentence_ids": [
12
],
"label": "CONTRADICT"
}
] | [
37480103
] |
1,268 | The risk of cancer rises with level of alcohol consumption. | [
{
"doc_id": 52072815,
"sentence_ids": [
8
],
"label": "SUPPORT"
},
{
"doc_id": 52072815,
"sentence_ids": [
11
],
"label": "SUPPORT"
}
] | [
52072815
] |
1,269 | The risk of female prisoners harming themselves is ten times that of male prisoners. | [
{
"doc_id": 13900610,
"sentence_ids": [
7
],
"label": "SUPPORT"
},
{
"doc_id": 13900610,
"sentence_ids": [
8
],
"label": "SUPPORT"
}
] | [
13900610
] |
1,275 | The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) is decorated with VgrG and PAAR proteins. | [] | [
27731651
] |
1,276 | The tissue surrounding the granuloma in an immune cell induces an anti-inflammatory immune response. | [
{
"doc_id": 3475317,
"sentence_ids": [
5
],
"label": "SUPPORT"
}
] | [
3475317
] |
1,284 | Therapeutics receiving accelerated approval encounter a lower frequency of post-marketing safety events | [
{
"doc_id": 3578380,
"sentence_ids": [
9
],
"label": "CONTRADICT"
}
] | [
3578380
] |
1,288 | There is a positive correlation between hip fractures and statin use. | [
{
"doc_id": 4687948,
"sentence_ids": [
7
],
"label": "CONTRADICT"
},
{
"doc_id": 4687948,
"sentence_ids": [
9
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"label": "CONTRADICT"
},
{
"doc_id": 4687948,
"sentence_ids": [
10
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"label": "CONTRADICT"
},
{
"doc_id": 4687948,
"sentence_ids": [
13
],
"label": "CONTRADICT"
}
] | [
4687948
] |
1,289 | There is a relation between Erythromycin use and hypertrophic pyloric stenosis. | [
{
"doc_id": 21239672,
"sentence_ids": [
9
],
"label": "SUPPORT"
},
{
"doc_id": 21239672,
"sentence_ids": [
10
],
"label": "SUPPORT"
}
] | [
21239672
] |
1,291 | There is no association between HNF4A mutations and diabetes risks. | [] | [
56893404
] |
1,293 | There is no increased risk of hypospadias with clomiphene. | [
{
"doc_id": 43329366,
"sentence_ids": [
1
],
"label": "CONTRADICT"
}
] | [
43329366
] |
1,294 | There is no known interaction between Pioneer factor OCT3/4 and major chromatin remodeling factors. | [
{
"doc_id": 2078658,
"sentence_ids": [
3
],
"label": "CONTRADICT"
},
{
"doc_id": 30507607,
"sentence_ids": [
3
],
"label": "CONTRADICT"
}
] | [
2078658,
30507607
] |
1,295 | There is no relation between Erythromycin use and hypertrophic pyloric stenosis. | [
{
"doc_id": 21239672,
"sentence_ids": [
9
],
"label": "CONTRADICT"
},
{
"doc_id": 21239672,
"sentence_ids": [
10
],
"label": "CONTRADICT"
}
] | [
21239672
] |
1,297 | There was an estimated 30 million cases of pneumonia in young children worldwide in 2010. | [
{
"doc_id": 9167230,
"sentence_ids": [
5
],
"label": "SUPPORT"
}
] | [
9167230
] |
1,300 | Thiopurine active metabolites can be catabolized through dephosphorylation of thioguanine nucleotides. | [] | [
6421792
] |
1,302 | Tirasemtiv has no effect on cardiac muscle. | [] | [
12631697
] |
1,304 | Tirasemtiv targets cardiac muscle. | [] | [
12631697
] |
1,305 | Tirasemtiv targets fast-twitch muscle. | [
{
"doc_id": 12631697,
"sentence_ids": [
1
],
"label": "SUPPORT"
},
{
"doc_id": 12631697,
"sentence_ids": [
2
],
"label": "SUPPORT"
}
] | [
12631697
] |
1,306 | Toll-like receptor (TLR) signaling is involved in the pathogenesis of human MDS. | [] | [
6000423,
5836
] |
1,307 | Tonic signaling from the scFv induces constitutive stimulation. | [] | [
18231807
] |
1,308 | Tonic signaling from the scFv is amplified by MyD88/CD40. | [] | [
18231807
] |
1,309 | Tonic signaling from the scFv prevents constitutive stimulation. | [] | [
18231807
] |
1,310 | Traditional reviews are biased in their interpretations. | [] | [
8042158
] |
1,311 | Trans-acting factors, such as lncRNAs, influence mRNA translation. | [
{
"doc_id": 13763195,
"sentence_ids": [
1
],
"label": "SUPPORT"
},
{
"doc_id": 13763195,
"sentence_ids": [
3
],
"label": "SUPPORT"
},
{
"doc_id": 13763195,
"sentence_ids": [
4
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{
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5
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},
{
"doc_id": 13763195,
"sentence_ids": [
6
],
"label": "SUPPORT"
}
] | [
13763195
] |
1,312 | Transcription factor EB induces transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus. | [
{
"doc_id": 24177706,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
24177706
] |
1,314 | Transcription rates in S. cerevisiae range between 0.7 and 2 kb/min. | [] | [
13072112,
16237005
] |
1,315 | Transcription rates in S. cerevisiae range between 7 and 12 kb/min. | [] | [
13072112,
16237005
] |
1,322 | Transplanted human glial progenitor cells can mature in their host animal. | [
{
"doc_id": 16284655,
"sentence_ids": [
2
],
"label": "SUPPORT"
}
] | [
16284655
] |
1,323 | Treatment with a protein named FN impairs regenerative abilities of aged muscles. | [
{
"doc_id": 19912367,
"sentence_ids": [
2
],
"label": "CONTRADICT"
},
{
"doc_id": 19912367,
"sentence_ids": [
4
],
"label": "CONTRADICT"
}
] | [
19912367
] |
1,324 | Treatment with a protein named FN restores regenerative abilities of aged muscles. | [
{
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"sentence_ids": [
2
],
"label": "SUPPORT"
},
{
"doc_id": 19912367,
"sentence_ids": [
4
],
"label": "SUPPORT"
}
] | [
19912367
] |
1,325 | Treatment with the EC uptake inhibitor AM404 resulted in a dose-dependent decrease in the expression of immobility. | [] | [
40476126
] |
1,327 | Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK. | [
{
"doc_id": 24241932,
"sentence_ids": [
6
],
"label": "CONTRADICT"
},
{
"doc_id": 24241932,
"sentence_ids": [
7
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"label": "CONTRADICT"
},
{
"doc_id": 22194407,
"sentence_ids": [
3
],
"label": "CONTRADICT"
},
{
"doc_id": 22194407,
"sentence_ids": [
9
],
"label": "CONTRADICT"
}
] | [
24241932,
22194407
] |
1,328 | Tuberculosis-induced granulomas express different immune system protein signatures than the surrounding tissue. | [
{
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"sentence_ids": [
4,
5
],
"label": "SUPPORT"
},
{
"doc_id": 3475317,
"sentence_ids": [
7
],
"label": "SUPPORT"
}
] | [
3475317
] |
1,330 | Tumor development occurs in conjunction with suppression of pro-inflammatory cytokines. | [] | [
14075252
] |
1,331 | Tumor development occurs in conjunction with upregulation of pro-inflammatory cytokines. | [] | [
14075252
] |
1,333 | Two variants of chromosome 6q21 are associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients. | [
{
"doc_id": 1649738,
"sentence_ids": [
1
],
"label": "SUPPORT"
}
] | [
1649738
] |
1,334 | Type 1 Diabetes is associated with subtle perturbations in T reg development. | [
{
"doc_id": 13940200,
"sentence_ids": [
2
],
"label": "SUPPORT"
},
{
"doc_id": 13940200,
"sentence_ids": [
3
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"label": "SUPPORT"
},
{
"doc_id": 11899391,
"sentence_ids": [
0
],
"label": "SUPPORT"
}
] | [
13923140,
13940200,
11899391
] |
1,340 | Ultrasound guidance significantly reduces the number of needle insertion attempts necessary for a given procedure. | [
{
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"sentence_ids": [
9
],
"label": "SUPPORT"
},
{
"doc_id": 15482274,
"sentence_ids": [
10
],
"label": "SUPPORT"
}
] | [
15482274
] |
1,341 | Ultrasound guidance significantly reduces the number of traumatic procedures when attempting needle insertion. | [
{
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"sentence_ids": [
7,
8,
9
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"label": "SUPPORT"
},
{
"doc_id": 15482274,
"sentence_ids": [
10
],
"label": "SUPPORT"
}
] | [
15482274
] |
1,342 | Understanding epigenetic regulation of replication is essential for the reational design of episomally replicating vectors. | [] | [
8148122
] |
1,345 | Up-regulation of the p53 pathway and related molecular events speeds cancer progression. | [] | [
9559146
] |
1,346 | Upon developing tyrosine-kinase inhibitor resistance, new mutations in epidermal growth factor receptors emerge and cause treatment failure. | [
{
"doc_id": 9505402,
"sentence_ids": [
1
],
"label": "SUPPORT"
},
{
"doc_id": 9505402,
"sentence_ids": [
3
],
"label": "SUPPORT"
}
] | [
9505402
] |
1,347 | Upon viral challenge, influenza-specific memory CD4+ T cells greatly diminish the early production of inflammatory chemokines in the lung. | [
{
"doc_id": 19005293,
"sentence_ids": [
2
],
"label": "CONTRADICT"
}
] | [
19005293
] |
1,348 | Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung. | [
{
"doc_id": 19005293,
"sentence_ids": [
2
],
"label": "SUPPORT"
}
] | [
19005293
] |
1,349 | Upregulation of PD1 causes the downmodulation of Satb1. | [] | [
5377642
] |
1,350 | Upregulation of PD1 causes the upregulation of Satb1. | [] | [
5377642
] |
1,351 | Upregulation of dynein in Drosophila neurons increases the number of microtubule plus-ends growing toward the cell body of each neuron. | [
{
"doc_id": 28369117,
"sentence_ids": [
4
],
"label": "CONTRADICT"
}
] | [
28369117
] |
1,353 | Urbanization is an important risk factor related to the transmission of dengue fever. | [] | [
18816720
] |
1,355 | V-9302 inhibits antitumor responses by decreasing cell death and oxidative stress. | [
{
"doc_id": 5256564,
"sentence_ids": [
4
],
"label": "CONTRADICT"
}
] | [
5256564
] |
1,356 | Vaccinating the gastrointestinal tract induces protection of rectal and vaginal mucosa. | [
{
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"sentence_ids": [
1
],
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},
{
"doc_id": 13764090,
"sentence_ids": [
3
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},
{
"doc_id": 13764090,
"sentence_ids": [
5
],
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}
] | [
13764090
] |
1,360 | Varenicline monotherapy is more effective after 26 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion. | [
{
"doc_id": 11614737,
"sentence_ids": [
9
],
"label": "CONTRADICT"
}
] | [
11614737
] |
1,361 | Varying expression levels of EBI2 affect the positioning and migration of B cells. | [
{
"doc_id": 15488881,
"sentence_ids": [
2,
3
],
"label": "SUPPORT"
},
{
"doc_id": 15058155,
"sentence_ids": [
3
],
"label": "SUPPORT"
}
] | [
15488881,
15058155
] |
1,364 | Venules have less significant tunica adventitia than arterioles. | [] | [
8290953
] |
1,366 | VgrG (Tssl) protein punctures membranes by forming a spike at the tip of the tube apparatus. | [
{
"doc_id": 4406819,
"sentence_ids": [
2,
4
],
"label": "SUPPORT"
}
] | [
4406819
] |
1,367 | Vitamin D deficiency effects birth weight. | [
{
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"sentence_ids": [
10
],
"label": "SUPPORT"
},
{
"doc_id": 2425364,
"sentence_ids": [
12
],
"label": "SUPPORT"
}
] | [
2425364
] |
1,371 | Vitamin D is an important factor in the relationship between calcium and parathyroid hormone. | [
{
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"sentence_ids": [
7
],
"label": "SUPPORT"
},
{
"doc_id": 16256507,
"sentence_ids": [
8
],
"label": "SUPPORT"
}
] | [
16256507
] |
1,372 | Walking in traffic areas in London did not improve lung function in elderly adults. | [
{
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"sentence_ids": [
10
],
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},
{
"doc_id": 21003930,
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11,
12
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},
{
"doc_id": 21003930,
"sentence_ids": [
15
],
"label": "SUPPORT"
}
] | [
21003930
] |
1,373 | Walking in traffic areas in London improves lung function in elderly adults. | [
{
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10
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},
{
"doc_id": 21003930,
"sentence_ids": [
11,
12
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"label": "CONTRADICT"
},
{
"doc_id": 21003930,
"sentence_ids": [
15
],
"label": "CONTRADICT"
}
] | [
21003930
] |
1,374 | Weighed food records (WFR) result in high completion since they're cheap to run and impose low participant burden. | [] | [
21993510
] |
1,375 | Weighed food records (WFR) result in poor completion since they're costly to run and impose high participant burden. | [] | [
21993510
] |
1,376 | Whole brain radiotherapy increases the occurrence of new brain metastases. | [
{
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"sentence_ids": [
6
],
"label": "CONTRADICT"
},
{
"doc_id": 3944632,
"sentence_ids": [
10
],
"label": "CONTRADICT"
}
] | [
3944632
] |
1,378 | Women are more susceptible to death due to pneumonia when compared to men. | [
{
"doc_id": 2488880,
"sentence_ids": [
10
],
"label": "SUPPORT"
}
] | [
2488880
] |
1,380 | Women with a lower birth weight are more likely to develop breast cancer later in life. | [
{
"doc_id": 16322674,
"sentence_ids": [
5
],
"label": "CONTRADICT"
},
{
"doc_id": 16322674,
"sentence_ids": [
6
],
"label": "CONTRADICT"
},
{
"doc_id": 23557241,
"sentence_ids": [
6
],
"label": "CONTRADICT"
},
{
"doc_id": 17450673,
"sentence_ids": [
5
],
"label": "CONTRADICT"
}
] | [
16322674,
23557241,
17450673
] |
1,381 | YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis. | [
{
"doc_id": 13481880,
"sentence_ids": [
4
],
"label": "SUPPORT"
},
{
"doc_id": 13481880,
"sentence_ids": [
5
],
"label": "SUPPORT"
}
] | [
13481880
] |
1,383 | aPKCz causes tumour suppression by affecting glutamine metabolism. | [
{
"doc_id": 17755060,
"sentence_ids": [
3
],
"label": "SUPPORT"
},
{
"doc_id": 17755060,
"sentence_ids": [
5
],
"label": "SUPPORT"
}
] | [
17755060
] |
1,386 | cSMAC formation represses weak ligand signalling. | [
{
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1,387 | eRNAs influence is linked to senescence, aging, and carcinogenesis. | [] | [
9669099
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1,390 | mcm 5 s 2 U is required for proper decoding of NNR codons in eukaryotes. | [
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1,391 | miR-142-5P is a known regulator of raised body temperature. | [
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6766459
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1,392 | miR-142-5P is a temperature-sensitive microRNA (miRNA). | [
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1,393 | miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription. | [
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1,394 | miRNAs regulate a unique suite of mRNAs to maintain homeostasis in cells. | [] | [
2251426
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1,397 | p16INK4A degradation is linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs). | [] | [
17717391
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