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m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina
developmental biology
Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation
genetics
MuSiC2: cell type deconvolution for multi-condition bulk RNA-seq data
genomics
Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology
biochemistry
Characterization of a nanobody-epitope tag interaction and its application for receptor engineering
biochemistry
Attention-wise masked graph contrastive learning for predicting molecular property
bioinformatics
A framework for summarizing chromatin state annotations within and identifying differential annotations across groups of samples
bioinformatics
Integrated Analysis of Tissue-specific Gene Expression in Diabetes by Tensor Decomposition-based Unsupervised Feature Extraction with Standard Deviation Optimization Can Identify Possible Associated Diseases.
bioinformatics
Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
cancer biology
Intracortical remodelling increases in highly-loaded bone after exercise cessation
physiology
Characteristics and Impact of the rNST GABA Network on Neural and Behavioral Taste Responses
neuroscience
Adversarial interspecies relationships facilitate population suppression by gene drive in spatially explicit models
ecology
Resting-state network hubs are causally required in memory consolidation
animal behavior and cognition
Assembly-free discovery of human novel sequences using long reads
bioinformatics
MAGNETO: an automated workflow for genome-resolved metagenomics
bioinformatics
Cryo-EM structure of gas vesicles for buoyancy-controlled motility
biophysics
Multi-policy models of interregional communication in the human connectome
neuroscience
Comparative brain structure and the neural network features of cuttlefish and squid
neuroscience
Closed-loop and automatic tuning of pulse amplitude and width in EMG-guided controllable transcranial magnetic stimulation (cTMS)
neuroscience
Two complete genomes of male-killing Wolbachia infecting Ostrinia moth species illuminate their evolutionary dynamics and association with hosts
microbiology
Spontaneously produced lysogenic phages are an important component of the soybean Bradyrhizobium mobilome
microbiology
Skeletal muscle cells derived from induced pluripotent stem cells: a platform for limb girdle muscular dystrophies.
cell biology
Evolution and diversity of the TopoVI and TopoVI-like subunits with extensive divergence of the TOPOVIBL subunit
evolutionary biology
Population genomics provide insights into the global genetic structure of Colletotrichum graminicola, the causal agent of maize anthracnose
genomics
Single-molecule architecture and heterogeneity of human telomeric DNA and chromatin
genomics
Single-Cell RNAseq Analysis Reveals Robust Anti-PD-1-Mediated Increase of Immune Infiltrate in Metastatic Castration-Sensitive Prostate Cancer
cancer biology
Reproducibility of in-vivo electrophysiological measurements in mice
neuroscience
Single-cell profiling coupled with lineage analysis reveals distinct sacral neural crest contributions to the developing enteric nervous
developmental biology
Scaled-expansion of the membrane associated cytoskeleton requires conserved kinesin adaptors
cell biology
A new model of Notch signaling: Control of Notch receptor cis-inhibition via Notch ligand dimers
cell biology
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
cell biology
Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data
cell biology
Prenatal inflammation perturbs fetal hematopoietic development and causes persistent changes to postnatal immunity
cell biology
Rapid covalent labeling of a GPCR on living cells using a nanobody-epitope tag pair to interrogate receptor pharmacology
biochemistry
Sampling biases obscure the early diversification of the largest living vertebrate group
paleontology
Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation
cell biology
A sporulation-independent way of life for Bacillus thuringiensis in the late stages of an infection
microbiology
Thermal endurance by a hot-spring-dwelling phylogenetic relative of the mesophilic Paracoccus
microbiology
Chemoenzymatic fluorescence labeling of intercellularly contacting cells using lipidated sortase A
biochemistry
Roughening instability of growing 3D bacterial colonies
biophysics
Deformable Mirror based Optimal PSF Engineering for 3D Super-resolution Imaging
biophysics
Computational modeling of TGF-β2:TβRI:TβRII receptor complex assembly as mediated by the TGF-β co-receptor betaglycan
biophysics
De novo design of peptides that form transmembrane barrel pores killing antibiotic resistant bacteria
biophysics
Derivation of the Relationship Between the Mass and Lifespan of Living Organisms
biophysics
Sequence-based pH-dependent prediction of protein solubility using CamSol
biophysics
Evolution avoids a pathological stabilizing interaction in the immune protein S100A9
biophysics
Ubiquitous bacterial polyketides induce cross-kingdom microbial interactions
microbiology
Corynebacterium matruchotii fitness enhancement of adjacent streptococci by multiple mechanisms
microbiology
In-silico identification of Tyr232 in AMPKα2 as a dephosphorylation site for the protein tyrosine phosphatase PTP-PEST
biochemistry
Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack
biophysics
Decoding The Nuclear Genome of The Human Pathogen Babesia duncani Shed Light on its Virulence, Drug Susceptibility and Evolution among Apicomplexa
microbiology
Identification of Banana heat responsive long non-coding RNAs and their gene expression analysis.
molecular biology
Chronic clinical signs of upper respiratory tract disease shape gut and respiratory microbiomes in cohabitating domestic felines.
microbiology
The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters
genetics
Real-time single-molecule observation of chaperone-assisted protein folding
biochemistry
Design of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography
biophysics
Deep Reinforcement Learning for Optimal Experimental Design in Biology
synthetic biology
Persistent serum protein signatures define an inflammatory subset of long COVID
immunology
SARS-CoV-2 Spike N-Terminal Domain modulates TMPRSS2-dependent viral entry and fusogenicity
microbiology
Soil nitrogen impacts the rhizosphere microbial community owing to microbial hitchhiking
microbiology
A marine probiotic treatment against the bacterial pathogen Vibrio coralliilyticus to improve the performance of Pacific (Crassostrea gigas) and Kumamoto (C. sikamea) oyster larvae
microbiology
SIRT3 deficiency decreases oxidative-metabolism capacity but increases lifespan under caloric restriction
molecular biology
Developmentally regulated alternate 3' end cleavage of nascent transcripts controls dynamic changes in protein expression in an adult stem cell lineage
developmental biology
Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responses
developmental biology
Inferring selection effects in SARS-CoV-2 with Bayesian Viral Allele Selection
genomics
Deciphering the Impact of Genetic Variation on Human Polyadenylation
genomics
Liquid-like assembly of VASP drives actin polymerization and bundling
biophysics
Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter
biophysics
A novel ALDH1A1 inhibitor blocks platinum-induced senescence and stemness in ovarian cancer
cancer biology
Integrative multi-omics analysis reveals molecular subtypes and tumor evolution of synovial sarcoma
cancer biology
A requirement for Kruppel-Like Factor-4 in the maintenance of endothelial cell quiescence
physiology
The Role of Conjunctive Representations in Prioritizing and Selecting Planned Actions
neuroscience
Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells
neuroscience
The evolution of information transmission in mammalian brain networks
neuroscience
Neuroinflammation plays a critical role in cerebral cavernous malformation disease
neuroscience
Species sympatry shapes brain size evolution in Primates
ecology
Mutation rates and fitness consequences of mosaic chromosomal alterations in blood
genomics
The effect of sociality on competitive interactions among birds
animal behavior and cognition
TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons
physiology
Cellular And Molecular Effects Of Understudied Kinase Pregnancy Upregulated Non-Ubiquitous Calcium-Calmodulin Dependent Kinase (PNCK) In Renal Cell Carcinoma.
molecular biology
Molecular architecture of the C. elegans centriole
cell biology
Structure of maize BZR1-type β-amylase BAM8 provides new insights into its noncatalytic adaptation
biochemistry
MPZ-T124M mouse model replicates human axonopathy and suggest alteration in axo-glia communication
neuroscience
The endothelial-specific LINC00607 mediates endothelial angiogenic function
molecular biology
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson's disease data
genetics
Chromosome-scale assembly of the lablab genome - A model for inclusive orphan crop genomics
genomics
spSeudoMap: Cell type mapping of spatial transcriptomics using unmatched single-cell RNA-seq data
genomics