Datasets:

bigbio

/

biorelex

like 2

[ { "id": "1.0alpha7.train.1400.sent", "type": "sentence", "text": [ " Top, Rac activation was demonstrated by a PAK-affinity precipitation assay using a GST-PAK-PBD fusion protein that binds to GTP-bound activated Rac. " ], "offsets": [ [ 0, 156 ] ] } ]

[ { "id": "1.0alpha7.train.1400.ent0_0", "type": "experimental-construct", "text": [ "GST-PAK-PBD" ], "offsets": [ [ 87, 98 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1400.ent1_0", "type": "protein", "text": [ "Rac" ], "offsets": [ [ 7, 10 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5879" }, { "db_name": "hgnc", "db_id": "RAC1" }, { "db_name": "uniprot", "db_id": "P63000" } ] }, { "id": "1.0alpha7.train.1400.ent2_1", "type": "protein", "text": [ "Rac" ], "offsets": [ [ 150, 153 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5879" }, { "db_name": "hgnc", "db_id": "RAC1" }, { "db_name": "uniprot", "db_id": "P63000" } ] }, { "id": "1.0alpha7.train.1400.ent3_0", "type": "chemical", "text": [ "GTP" ], "offsets": [ [ 129, 132 ] ], "normalized": [ { "db_name": "pubchem:compound", "db_id": "135398633" } ] }, { "id": "1.0alpha7.train.1400.ent4_0", "type": "protein-domain", "text": [ "PBD" ], "offsets": [ [ 95, 98 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1400.ent5_0", "type": "protein", "text": [ "GTP-bound activated Rac" ], "offsets": [ [ 129, 153 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1400.ent6_0", "type": "assay", "text": [ "PAK-affinity precipitation assay" ], "offsets": [ [ 45, 77 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1400.ent7_0", "type": "protein-family", "text": [ "PAK" ], "offsets": [ [ 45, 48 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5058" }, { "db_name": "hgnc", "db_id": "PAK1" }, { "db_name": "uniprot", "db_id": "Q13153" } ] }, { "id": "1.0alpha7.train.1400.ent8_1", "type": "protein-family", "text": [ "PAK" ], "offsets": [ [ 91, 94 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5058" }, { "db_name": "hgnc", "db_id": "PAK1" }, { "db_name": "uniprot", "db_id": "Q13153" } ] } ]

[]

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[ { "id": "1.0alpha7.train.1400.rel0s1.0alpha7.train.1400.ent0_0.o1.0alpha7.train.1400.ent5_0", "type": "bind", "arg1_id": "1.0alpha7.train.1400.ent0_0", "arg2_id": "1.0alpha7.train.1400.ent5_0", "normalized": [] }, { "id": "1.0alpha7.train.1400.rel1s1.0alpha7.train.1400.ent1_0.o1.0alpha7.train.1400.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.1400.ent1_0", "arg2_id": "1.0alpha7.train.1400.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.1400.rel1s1.0alpha7.train.1400.ent2_1.o1.0alpha7.train.1400.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.1400.ent2_1", "arg2_id": "1.0alpha7.train.1400.ent3_0", "normalized": [] } ]

[ { "id": "1.0alpha7.train.1401.sent", "type": "sentence", "text": [ "We find that the molecular chaperones p23 and Hsp90 bind to hTERT and are associated with active telomerase in cells." ], "offsets": [ [ 0, 120 ] ] } ]

[ { "id": "1.0alpha7.train.1401.ent0_0", "type": "protein-complex", "text": [ "telomerase" ], "offsets": [ [ 100, 110 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1401.ent1_0", "type": "protein", "text": [ "hTERT" ], "offsets": [ [ 63, 68 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "7015" }, { "db_name": "hgnc", "db_id": "TERT" }, { "db_name": "uniprot", "db_id": "O14746" } ] }, { "id": "1.0alpha7.train.1401.ent2_0", "type": "protein", "text": [ "Hsp90" ], "offsets": [ [ 48, 53 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "3320" }, { "db_name": "hgnc", "db_id": "HSP90AA1" }, { "db_name": "uniprot", "db_id": "P07900" } ] }, { "id": "1.0alpha7.train.1401.ent3_0", "type": "protein", "text": [ "p23" ], "offsets": [ [ 39, 42 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "10728" }, { "db_name": "hgnc", "db_id": "PTGES3" }, { "db_name": "uniprot", "db_id": "Q15185" } ] } ]

[]

[ { "id": "1.0alpha7.train.1401.coref0", "entity_ids": [ "1.0alpha7.train.1401.ent0_0" ] }, { "id": "1.0alpha7.train.1401.coref1", "entity_ids": [ "1.0alpha7.train.1401.ent1_0" ] }, { "id": "1.0alpha7.train.1401.coref2", "entity_ids": [ "1.0alpha7.train.1401.ent2_0" ] }, { "id": "1.0alpha7.train.1401.coref3", "entity_ids": [ "1.0alpha7.train.1401.ent3_0" ] } ]

[ { "id": "1.0alpha7.train.1401.rel0s1.0alpha7.train.1401.ent1_0.o1.0alpha7.train.1401.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.1401.ent1_0", "arg2_id": "1.0alpha7.train.1401.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.1401.rel1s1.0alpha7.train.1401.ent1_0.o1.0alpha7.train.1401.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.1401.ent1_0", "arg2_id": "1.0alpha7.train.1401.ent2_0", "normalized": [] } ]

[ { "id": "1.0alpha7.train.1402.sent", "type": "sentence", "text": [ " JIP1 binds to JNK, the MAP kinase kinase MKK7, and members of the mixed-lineage protein kinase group of MAP kinase kinase kinases (Whitmarsh et al. 1998 ). " ], "offsets": [ [ 0, 162 ] ] } ]

[ { "id": "1.0alpha7.train.1402.ent0_0", "type": "protein", "text": [ "JNK" ], "offsets": [ [ 16, 19 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5599" }, { "db_name": "hgnc", "db_id": "MAPK8" }, { "db_name": "uniprot", "db_id": "P45983" } ] }, { "id": "1.0alpha7.train.1402.ent1_0", "type": "protein", "text": [ "JIP1" ], "offsets": [ [ 1, 5 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "9479" }, { "db_name": "hgnc", "db_id": "MAPK8IP1" }, { "db_name": "uniprot", "db_id": "Q9UQF2" } ] }, { "id": "1.0alpha7.train.1402.ent2_0", "type": "protein-family", "text": [ "MAP kinase kinase kinases" ], "offsets": [ [ 108, 133 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1402.ent3_0", "type": "protein", "text": [ "MAP kinase kinase MKK7" ], "offsets": [ [ 26, 48 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5609" }, { "db_name": "hgnc", "db_id": "MAP2K7" }, { "db_name": "uniprot", "db_id": "O14733" } ] } ]

[]

[ { "id": "1.0alpha7.train.1402.coref0", "entity_ids": [ "1.0alpha7.train.1402.ent0_0" ] }, { "id": "1.0alpha7.train.1402.coref1", "entity_ids": [ "1.0alpha7.train.1402.ent1_0" ] }, { "id": "1.0alpha7.train.1402.coref2", "entity_ids": [ "1.0alpha7.train.1402.ent2_0" ] }, { "id": "1.0alpha7.train.1402.coref3", "entity_ids": [ "1.0alpha7.train.1402.ent3_0" ] } ]

[ { "id": "1.0alpha7.train.1402.rel0s1.0alpha7.train.1402.ent0_0.o1.0alpha7.train.1402.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.1402.ent0_0", "arg2_id": "1.0alpha7.train.1402.ent1_0", "normalized": [] }, { "id": "1.0alpha7.train.1402.rel1s1.0alpha7.train.1402.ent1_0.o1.0alpha7.train.1402.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.1402.ent1_0", "arg2_id": "1.0alpha7.train.1402.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.1402.rel2s1.0alpha7.train.1402.ent1_0.o1.0alpha7.train.1402.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.1402.ent1_0", "arg2_id": "1.0alpha7.train.1402.ent2_0", "normalized": [] } ]

[ { "id": "1.0alpha7.train.1403.sent", "type": "sentence", "text": [ "c-Jun binds TAFII250 with high specificity." ], "offsets": [ [ 0, 44 ] ] } ]

[ { "id": "1.0alpha7.train.1403.ent0_0", "type": "protein", "text": [ "TAFII250" ], "offsets": [ [ 13, 21 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P51123" } ] }, { "id": "1.0alpha7.train.1403.ent1_0", "type": "protein", "text": [ "c-Jun" ], "offsets": [ [ 0, 5 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "3725" }, { "db_name": "hgnc", "db_id": "JUN" }, { "db_name": "uniprot", "db_id": "P05412" } ] } ]

[]

[ { "id": "1.0alpha7.train.1403.coref0", "entity_ids": [ "1.0alpha7.train.1403.ent0_0" ] }, { "id": "1.0alpha7.train.1403.coref1", "entity_ids": [ "1.0alpha7.train.1403.ent1_0" ] } ]

[ { "id": "1.0alpha7.train.1403.rel0s1.0alpha7.train.1403.ent0_0.o1.0alpha7.train.1403.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.1403.ent0_0", "arg2_id": "1.0alpha7.train.1403.ent1_0", "normalized": [] } ]

[ { "id": "1.0alpha7.train.1404.sent", "type": "sentence", "text": [ " Paxillin binds to vinculin, alpha-actinin, and talin and therefore, like FAK, may help direct actin filament (F-actin)-membrane interactions( 13, 14) . " ], "offsets": [ [ 0, 161 ] ] } ]

[ { "id": "1.0alpha7.train.1404.ent0_0", "type": "protein", "text": [ "talin" ], "offsets": [ [ 52, 57 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "7094" }, { "db_name": "hgnc", "db_id": "TLN1" }, { "db_name": "uniprot", "db_id": "Q9Y490" } ] }, { "id": "1.0alpha7.train.1404.ent1_0", "type": "protein", "text": [ "actin filament" ], "offsets": [ [ 101, 116 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1404.ent2_0", "type": "protein", "text": [ "F-actin" ], "offsets": [ [ 118, 125 ] ], "normalized": [] }, { "id": "1.0alpha7.train.1404.ent3_0", "type": "protein", "text": [ "vinculin" ], "offsets": [ [ 20, 28 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "7414" }, { "db_name": "hgnc", "db_id": "VCL" }, { "db_name": "uniprot", "db_id": "P18206" } ] }, { "id": "1.0alpha7.train.1404.ent4_0", "type": "protein-family", "text": [ "alpha-actinin" ], "offsets": [ [ 32, 45 ] ], "normalized": [ { "db_name": "interpro", "db_id": "IPR026921" } ] }, { "id": "1.0alpha7.train.1404.ent5_0", "type": "protein", "text": [ "Paxillin" ], "offsets": [ [ 1, 9 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5829" }, { "db_name": "hgnc", "db_id": "PXN" }, { "db_name": "uniprot", "db_id": "P49023" } ] }, { "id": "1.0alpha7.train.1404.ent6_0", "type": "protein", "text": [ "FAK" ], "offsets": [ [ 79, 82 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5747" }, { "db_name": "hgnc", "db_id": "PTK2" }, { "db_name": "uniprot", "db_id": "Q05397" } ] }, { "id": "1.0alpha7.train.1404.ent7_0", "type": "protein-family", "text": [ "actin" ], "offsets": [ [ 101, 106 ] ], "normalized": [ { "db_name": "pfam", "db_id": "PF00022" } ] }, { "id": "1.0alpha7.train.1404.ent8_1", "type": "protein-family", "text": [ "actin" ], "offsets": [ [ 120, 125 ] ], "normalized": [ { "db_name": "pfam", "db_id": "PF00022" } ] } ]

[]

[ { "id": "1.0alpha7.train.1404.coref0", "entity_ids": [ "1.0alpha7.train.1404.ent0_0" ] }, { "id": "1.0alpha7.train.1404.coref1", "entity_ids": [ "1.0alpha7.train.1404.ent1_0", "1.0alpha7.train.1404.ent2_0" ] }, { "id": "1.0alpha7.train.1404.coref2", "entity_ids": [ "1.0alpha7.train.1404.ent3_0" ] }, { "id": "1.0alpha7.train.1404.coref3", "entity_ids": [ "1.0alpha7.train.1404.ent4_0" ] }, { "id": "1.0alpha7.train.1404.coref4", "entity_ids": [ "1.0alpha7.train.1404.ent5_0" ] }, { "id": "1.0alpha7.train.1404.coref5", "entity_ids": [ "1.0alpha7.train.1404.ent6_0" ] }, { "id": "1.0alpha7.train.1404.coref6", "entity_ids": [ "1.0alpha7.train.1404.ent7_0", "1.0alpha7.train.1404.ent8_1" ] } ]

[ { "id": "1.0alpha7.train.1404.rel0s1.0alpha7.train.1404.ent3_0.o1.0alpha7.train.1404.ent5_0", "type": "bind", "arg1_id": "1.0alpha7.train.1404.ent3_0", "arg2_id": "1.0alpha7.train.1404.ent5_0", "normalized": [] }, { "id": "1.0alpha7.train.1404.rel1s1.0alpha7.train.1404.ent4_0.o1.0alpha7.train.1404.ent5_0", "type": "bind", "arg1_id": "1.0alpha7.train.1404.ent4_0", "arg2_id": "1.0alpha7.train.1404.ent5_0", "normalized": [] }, { "id": "1.0alpha7.train.1404.rel2s1.0alpha7.train.1404.ent0_0.o1.0alpha7.train.1404.ent5_0", "type": "bind", "arg1_id": "1.0alpha7.train.1404.ent0_0", "arg2_id": "1.0alpha7.train.1404.ent5_0", "normalized": [] } ]